The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Progression of Systolic Abnormalities in Patients With “Isolated” Diastolic Heart Failure and Diastolic Dysfunction
Abstract
Background — The definition of diastolic heart failure (DHF) relies on the use of sensitive tools to exclude the presence of systolic dysfunction. The use of ejection fraction (EF) of 50% as the cutoff point may not be adequate to address such a task. We believe that systolic dysfunction is common in DHF. Methods and Results — Echocardiography with tissue Doppler imaging was performed in 339 subjects, of whom 92 had systolic heart failure (SHF) (EF<50%), 73 had DHF (EF≥50% with diastolic abnormalities on Doppler echocardiography), and 68 had isolated diastolic dysfunction (DD); 106 were normal control subjects. Regional myocardial velocity curves were constructed off-line with the use of a 6-basal, 6-midsegmental model. The peak regional myocardial sustained systolic (S M ) and early diastolic (E M ) velocities were significantly lower in patients with SHF, DHF, and DD than in control subjects in almost all the myocardial segments. Likewise, the mean S M (SHF<DHF<DD<control subjects; 3.3±1.0<4.6±1.3<5.4±1.0<6.3±1.0 cm/s; all P ≤0.001) and mean E M (SHF=DHF<DD<control subjects; 3.6±1.2 =3.9±1.3<5.3±1.6<7.2±1.7 cm/s; all P <0.001) from the six basal segments were decreased in all the disease groups. A mean S M of 4.4cm/s (−2 SD of control subjects) predicted the presence of systolic dysfunction in 92% of patients with SHF, 52% with DHF, and 14% with DD. Conclusions — Through the use of tissue Doppler imaging, systolic abnormalities were evident in patients previously labeled as DHF and to a much lesser extent, isolated DD. This indicates the common coexistence of systolic and diastolic dysfunction in a spectrum of different severity in the pathophysiological process of heart failure.
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Cites
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Defining Diastolic Heart Failure: A Call for Standardized Diagnostic Criteria
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How to diagnose diastolic heart failure
Paulus, W. J., Brutsaert, D. L., Gillebert, T. C., Rademakers, F., Stanislas, U., Leite-Moreira, A. F., Om, H., Zh, J., Kaufmann, P. A., Mandinov, L., et al. (1998) · Ghent University Academic Bibliography (Ghent University) · Cited by 649
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How to diagnose diastolic heart failure
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Cited by
Paulus, W. J., Tschöpe, C., Sanderson, J. E., Rusconi, C., Flachskampf, F. A., Rademakers, F. E., Marino, P., Smiseth, O. A., De Keulenaer, G., Leite-Moreira, A. F., et al. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehm037 · Cited by 2,679
Impaired Systolic Function by Strain Imaging in Heart Failure With Preserved Ejection Fraction
Kraigher-Krainer, E., Shah, A. M., Gupta, D. K., Santos, A., Claggett, B., Pieske, B., Zile, M. R., Voors, A. A., Lefkowitz, M. P., Packer, M., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.09.052 · Cited by 756
The pathophysiology of heart failure with preserved ejection fraction
Borlaug, B. A. (2014) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2014.83 · Cited by 726
Borlaug, B. A., Melenovsky, V., Russell, S. D., Kessler, K., Pacak, K., Becker, L. C., & Kass, D. A. (2006) · Circulation · doi:10.1161/circulationaha.106.632745 · Cited by 699
Myocardial Structure and Function Differ in Systolic and Diastolic Heart Failure
van Heerebeek, L., Borbély, A., Niessen, H. W. M., Bronzwaer, J. G. F., van der Velden, J., Stienen, G. J. M., Linke, W. A., Laarman, G. J., & Paulus, W. J. (2006) · Circulation · doi:10.1161/circulationaha.105.587519 · Cited by 664
Metadata
- Authors
- Yu, C.-M., Lin, H., Yang, H., Kong, S.-L., Zhang, Q., & Lee, S. W.-L.
- Venue
- Circulation
- Published
- 2002-03-12
- Volume
- 105
- Issue
- 10
- Pages
- 1195-1201
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2055078469
- Cited by
- 511
- References
- 23
- FWCI
- 16.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yu, C.-M., Lin, H., Yang, H., Kong, S.-L., Zhang, Q., & Lee, S. W.-L. (2002). Progression of Systolic Abnormalities in Patients With “Isolated” Diastolic Heart Failure and Diastolic Dysfunction. Circulation. https://doi.org/10.1161/hc1002.105185
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