Cited by 207Protease and Inhibitor MechanismsRenin-Angiotensin System StudiesCardiac Fibrosis and Remodeling

Matrix metalloproteinases promote arterial remodeling in aging, hypertension, and atherosclerosis

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Wang, Mingyi, Kim, Soo Hyuk, Monticone, Robert E., Lakatta, Edward G.·2015·Hypertension

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Crossref · 10.1161/hypertensionaha.114.03618

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  • Plaque destabilization through cap thinning is promoted by various MMPs secreted as part of the SASP of senescent VSMCs, monocytes, macrophages, and foam cells.

    “Plaque destabilization through cap thinning is promoted by various MMPs,49 such as MMP-1, -2, -3, -7, -8, -9, -10, -12, -13, and -14,45,49,51 which are secreted as part of the SASP of senescent VSMCs, monocytes, macrophages, and foam cells.”

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Authors
Wang, M., Kim, S. H., Monticone, R. E., & Lakatta, E. G.
Affiliations
National Institutes of Health (US)
Venue
Hypertension
Published
2015-04
Volume
65
Issue
4
Pages
698-703
ISSN
  • 0194-911X (ISSN-L)
  • 1524-4563
OpenAlex
W2147065016
Cited by
207
References
74
Citations by year
2026: 16 · 2025: 21 · 2024: 19 · 2023: 12 · 2022: 15 · 2021: 17 · 2020: 21 · 2019: 21 · 2018: 22 · 2017: 22 · 2016: 17 · 2015: 4
FWCI
7.17
Type
journal article
Language
en
Open access
Locations
  • Hypertension (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health
  • National Institute on Aging (ZIAAG000239)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Protease and Inhibitor Mechanisms
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Renin-Angiotensin System Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
Keywords
matrix metalloproteinases, arterial remodeling, aging, atherosclerosis, vascular remodeling
MeSH terms
Aging, Animals, Arteries, Humans, Hypertension, Disease Progression, Matrix Metalloproteinases, Atherosclerosis, Vascular Remodeling

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