Years of Potential Life Lost Because of Cardiovascular Disease in Asian‐American Subgroups, 2003–2012

Iyer, Divya G.; Shah, Nilay S.; Hastings, Katherine G.; Hu, Jiaqi; Rodriguez, Fatima; Boothroyd, Derek B.; Krishnan, Aruna V.; Falasinnu, Titilola; Palaniappan, Latha

doi:10.1161/jaha.118.010744

Cited by 67Healthcare Systems and Public HealthCardiovascular Health and Risk FactorsHealth disparities and outcomes

Years of Potential Life Lost Because of Cardiovascular Disease in Asian‐American Subgroups, 2003–2012

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Iyer, Divya G., Shah, Nilay S., Hastings, Katherine G., Hu, Jiaqi, Rodriguez, Fatima, Boothroyd, Derek B., Krishnan, Aruna V., Falasinnu, Titilola +1 more·2019·Journal of the American Heart Association

DOI 10.1161/jaha.118.010744PMC PMC6509739

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Abstract

Background: Asian‐American subgroups (Asian‐Indian, Chinese, Filipino, Korean, Japanese, and Vietnamese) display varied cardiovascular disease mortality patterns, especially at younger ages. This study aims to examine the years of potential life lost because of ischemic heart disease and cerebrovascular disease among the 6 largest Asian‐American subgroups compared with non‐Hispanic whites. Methods and Results: We used National Center for Health Statistics Multiple Causes of Death mortality files from 2003 to 2012 to calculate race‐specific life expectancy, mean years of potential life lost, and years of potential life lost per 100 000 population for each Asian subgroup and non‐Hispanic whites. Asian‐American subgroups display heterogeneity in cardiovascular disease burden. Asian‐Indians had a high burden of ischemic heart disease; Asian‐Indian men lost 724 years per 100 000 population in 2012 and a mean of 17 years to ischemic heart disease. Respectively, Vietnamese and Filipino men and women lost a mean of 17 and 16 years of life to cerebrovascular disease; Filipino men lost 352 years per 100 000 population in 2012. All Asian subgroups for both sexes had higher years of life lost to cerebrovascular disease compared with non‐Hispanic whites. Conclusions: Cardiovascular disease burden varies among Asian subgroups, and contributes to greater premature mortality in certain subgroups. Asian‐Indian and Filipino populations have the highest years of life lost because of ischemic heart disease and Filipino and Vietnamese have the highest years of life lost because of cerebrovascular disease. Analysis of risk factors and development of subgroup‐specific interventions are required to address these health disparities.

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Emerging research suggests that some Asian subgroups, and Pacific Islanders, may be at higher risk for CVD and poorer outcomes than NHW, and that there are important differences among API subgroups.
“Emerging research suggests that some Asian subgroups, and Pacific Islanders, may be at higher risk for CVD and poorer outcomes than NHW, and that there are important differences among API subgroups [4-8].”
From Prevalence of cardiovascular disease among Asian, Pacific Islander and multi-race populations in Hawai’i and California (2023) · cites this paper as [4]
The Methods and Results report differences in CVD burden among Asian-American subgroups and higher years of life lost to cerebrovascular disease than among non-Hispanic whites. The Discussion also identifies Filipino and Vietnamese populations as having more years of life lost than the non-Hispanic white population studied. The paper does not report CVD risk or outcomes for Pacific Islanders, so it does not support that part of the sentence. (LLM, conf=0.89)
Experimental — accuracy not yet measured
Among Asian populations, study findings of higher prevalence of all three CVD conditions among Filipinos is consistent with previous reports of higher cardiometabolic risk and poorer health outcomes in this population.
“Among Asian populations, study findings of higher prevalence of all three CVD conditions among Filipinos is consistent with previous reports of higher cardiometabolic risk and poorer health outcomes in this population [4, 7, 13, 15, 19, 22, 30-34].”
From Prevalence of cardiovascular disease among Asian, Pacific Islander and multi-race populations in Hawai’i and California (2023) · cites this paper as [4]

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Additional file 5 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799863
Additional file 6 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799866
Additional file 11 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799827
Additional file 2 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799851
Additional file 1 of Prevalence of cardiovascular disease among Asian, Pacific Islander and multi-race populations in Hawai’i and California
Waitzfelder, B., Palaniappan, L. P., Varga, A., Frankland, T. B., Li, J., Daida, Y. G., Kaholokula, J. K., Bacong, A. M., Rawlings, A. M., Chung, S., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22826743
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Additional file 10 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799824
Additional file 1 of Were US Asian Indian decedents with atherosclerosis more likely to have concurrent diabetes mellitus? Analysis of national multiple cause of mortality data (2012–2019)
Nair, D. R., Chauhan, A., & Vaidya, D. (2022) · Figshare · doi:10.6084/m9.figshare.21430908
Additional file 7 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799869
Additional file 13 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799839
Additional file 8 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799872
Additional file 1 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799845
Additional file 4 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799857
Additional file 12 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799833
Additional file 3 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799854
Additional file 9 of Increased burden of cardiovascular disease in people with liver disease: unequal geographical variations, risk factors and excess years of life lost
Chang, W. H., Mueller, S. H., Chung, S., Foster, G. R., & Lai, A. G. (2022) · Figshare · doi:10.6084/m9.figshare.17799875
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Abstract P127: Years of Life Lost Due to Cardiovascular Disease Among Asian American Subgroups, 2003-2012
Iyer, D. G., & Palaniappan, L. P. (2019) · Circulation · doi:10.1161/circ.139.suppl_1.p127
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Cardiovascular and Cerebrovascular Disease Mortality in Asian American Subgroups
Shah, N. S., Xi, K., Kapphahn, K., Srinivasan, M., Au, T., Sathye, V., Vishal, V., Zhang, H., & Palaniappan, L. P. (2022) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.121.008651 · Cited by 99 · see citing works
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Cardiovascular Disease Mortality in Asian Americans
Jose, P. O., Frank, A. T. H., Kapphahn, K., Goldstein, B. A., Eggleston, K. N., Hastings, K. G., Cullen, M. R., & Palaniappan, L. P. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.08.048 · Cited by 305 · see citing works
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Shah, N. S., Tong, X., Loustalot, F. V., & Woodruff, R. C. (2025) · Annals of Epidemiology · doi:10.1016/j.annepidem.2025.05.001 · Cited by 2 · see citing works
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Abstract MP89: Cardiovascular and Stroke Mortality in Asian Americans (2003-2010)
Jose, P. O., Frank, A. T. H., Kapphahn, K., Goldstein, B. A., Eggleston, K. N., Cullen, M. R., & Palaniappan, L. P. (2014) · Circulation · doi:10.1161/circ.129.suppl_1.mp89
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Authors: Iyer, D. G., Shah, N. S., Hastings, K. G., Hu, J., Rodriguez, F., Boothroyd, D. B., Krishnan, A. V., Falasinnu, T., & Palaniappan, L.
Affiliations: University of Connecticut (US)
Stanford Medicine (US)
Division of Cardiovascular Medicine Stanford University Stanford CA
Corresponding author: Palaniappan, Latha
ORCID: Iyer, Divya G.
Shah, Nilay S.
Hastings, Katherine G.
Hu, Jiaqi
Boothroyd, Derek B.
Krishnan, Aruna V.
Falasinnu, Titilola
Palaniappan, Latha
Venue: Journal of the American Heart Association
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2019-04-02
Volume: 8
Issue: 7
Pages: e010744-e010744
ISSN: 2047-9980 (ISSN-L)
DOI: 10.1161/jaha.118.010744
PMC: PMC6509739
OpenAlex: W2924337196
Cited by: 67
References: 38
Citations by year: 2026: 4 · 2025: 8 · 2024: 5 · 2023: 7 · 2022: 29 · 2021: 9 · 2020: 4 · 2019: 1
FWCI: 8.18
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
Locations: Journal of the American Heart Association (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders: National Heart, Lung, and Blood Institute (K01HL144607, K24HL150476)
National Institute on Minority Health and Health Disparities (R01MD007012)
Topics: Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Social Sciences › Health › Health disparities and outcomes
Keywords: years of potential life lost, cardiovascular disease burden, Asian American subgroups, ischemic heart disease, cerebrovascular disease, premature mortality, Asian Indian Americans, Filipino Americans, Vietnamese Americans, Chinese Americans, Korean Americans, Japanese Americans, health disparities, life expectancy
MeSH terms: Aged, Aged, 80 and over, Asian, Cardiovascular Diseases, Cause of Death, Cerebrovascular Disorders, China, Female, Humans, India, Japan, Life Expectancy, Male, Middle Aged, Philippines, Sex Factors, United States, Vietnam, Myocardial Ischemia, White People, Republic of Korea

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Years of Potential Life Lost Because of Cardiovascular Disease in Asian‐American Subgroups, 2003–2012

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