Racial/ethnic differences in dyslipidemia patterns
Open accessAbstract
BACKGROUND: No studies have comprehensively examined the prevalence of dyslipidemia, a major risk factor for cardiovascular disease, among diverse racial/ethnic minority groups. The primary aim of this study was to identify racial/ethnic differences in dyslipidemia among minorities including Asian Americans (Asian Indian, Chinese, Filipino, Japanese, Korean, or Vietnamese), Mexican Americans, and blacks compared with non-Hispanic whites. METHODS AND RESULTS: Using a 3-year cross section (2008-2011), we identified 169 430 active primary care patients (35 years or older) from an outpatient healthcare organization in northern California. Age-standardized prevalence rates were calculated for 3 dyslipidemia subtypes: high triglycerides (fasting laboratory value ≥150 mg/dL), low levels of high-density lipoprotein cholesterol (fasting laboratory value <40 mg/dL [men] and <50 mg/dL [women]), and high levels of low-density lipoprotein cholesterol (fasting laboratory value ≥130 mg/dL or taking low-density lipoprotein-lowering agents). Odds ratios were calculated by multivariable logistic regression, with adjustment for patient characteristics (age, measured body mass index, smoking). Compared with non-Hispanic whites, every minority subgroup had an increased prevalence of high triglycerides except blacks. Most minority groups had an increased prevalence of low high-density lipoprotein cholesterol, except for Japanese and blacks. The prevalence of high low-density lipoprotein cholesterol was increased among Asian Indians, Filipinos, Japanese, and Vietnamese compared with non-Hispanic whites. CONCLUSIONS: Minority groups, except for blacks, were more likely to have high triglyceride/low high-density lipoprotein cholesterol dyslipidemia. Further research is needed to determine how racial/ethnic differences in dyslipidemia affect racial/ethnic differences in cardiovascular disease rates.
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On average, African-Americans have higher HDL-C and lower triglyceride levels.
“On average, African-Americans have higher HDL-C and lower triglyceride levels(72).”
From The CardioMetabolic Health Alliance (2015) · cites this paper as [72]
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- Authors
- Frank, A. T. H., Zhao, B., Jose, P. O., Azar, K. M. J., Fortmann, S. P., & Palaniappan, L. P.
- Affiliations
- Palo Alto Medical Foundation (US)
- Venue
- Circulation
- Published
- 2014-02-04
- Volume
- 129
- Issue
- 5
- Pages
- 570-579
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC4212818
- OpenAlex
- W1990793454
- Cited by
- 327
- References
- 49
- Citations by year
- 2026: 22 · 2025: 38 · 2024: 43 · 2023: 42 · 2022: 35 · 2021: 34 · 2020: 23 · 2019: 23 · 2018: 19 · 2017: 15 · 2016: 12 · 2015: 18 · 2014: 2
- FWCI
- 10.52
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK081371)
- Topics
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- dyslipidemia, racial and ethnic differences, Asian Americans, Mexican Americans, African Americans, triglyceride elevation, low HDL cholesterol, high LDL cholesterol, cardiovascular risk, primary care patients
- MeSH terms
- Adult, Aged, Asian, Black or African American, California, Cross-Sectional Studies, Ethnicity, Female, Humans, Cholesterol, HDL, Cholesterol, LDL, Male, Middle Aged, Risk Factors, Triglycerides, Mexican Americans, Black People, White People, Dyslipidemias
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