Association Between Stroke and Patients With Pelvic Inflammatory Disease: A Nationwide Population-Based Study in Taiwan
Abstract
Background and Purpose—: The aim of this study is to estimate the risk of stroke in a 3-year period after pelvic inflammatory disease (PID) using a nationwide population-based study. Methods—: Our study cohort consisted of all patients with a diagnosis of PID (N=64 515) between 2004 and 2005 with a control cohort (1:2) of age-matched controls (N=129 030). Each patient was tracked from hospitalization until the end of 2006. Cox regressions were performed to compute the 3-year stroke-free survival rates after adjusting for possible confounding factors. Results—: We found that women with PID were more likely to have strokes than the control population. After adjusting for potential confounding factors, the adjusted hazard ratio of stroke was 1.63 (95% CI, 1.45–1.85) for PID patients as compared to the general population cohort. Sensitivity analysis using a bootstrap approach further ensured the validity of the results of our study. Conclusions—: We concluded that patients with PID have an association with stroke. Further research is necessary to investigate the pathophysiology between PID and stroke.
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The exclusion of women with PID did not support findings of increased risk of CVD among women with PID reported in the literature.
“The exclusion of women with PID did not support findings of increased risk of CVD among women with PID reported in the literature. 17,34”
From Risk of cardiovascular outcomes among women with endometriosis in the United Kingdom: a retrospective matched cohort study (2021) · cites this paper as [34]
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- Authors
- Chen, P.-C., Tseng, T.-C., Hsieh, J.-Y., & Lin, H.-W.
- Affiliations
- Min Sheng General Hospital (TW)
- Venue
- Stroke
- Published
- 2011-07
- Volume
- 42
- Issue
- 7
- Pages
- 2074-2076
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W1972607262
- Cited by
- 23
- References
- 12
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 2 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 2 · 2012: 4
- FWCI
- 1.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Stroke (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Keywords
- pelvic inflammatory disease, stroke risk, women, stroke-free survival, hazard ratio
- MeSH terms
- Pelvic Inflammatory Disease, Adolescent, Adult, Female, Humans, Middle Aged, Regression Analysis, Risk, Taiwan, Cohort Studies, Proportional Hazards Models, Case-Control Studies, Disease-Free Survival, Stroke
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