The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Risk and Secondary Prevention of Stroke Recurrence: A Population-Base Cohort Study
Open accessAbstract
Background and Purpose: With recent advances in secondary prevention management, stroke recurrence rates may have changed substantially. We aim to estimate risks and trends of stroke recurrence over the past 2 decades in a population-based cohort of patients with stroke. Methods: Patients with a first-ever stroke between 1995 and 2018 in South London, United Kingdom (n=6052) were collected and analyzed. Rates of recurrent stroke with 95% CIs were stratified by 5-year period of index stroke and etiologic TOAST (Trial of ORG 10172 in Acute Stroke Treatment) subtype. Cumulative incidences were estimated and multivariate Cox models applied to examine associations of recurrence and recurrence-free survival. Results: The rate of stroke recurrence at 5 years reduced from 18% (95% CI, 15%–21%) in those who had their stroke in 1995 to 1999 to 12% (10%–15%) in 2000 to 2005, and no improvement since. Recurrence-free survival has improved (35%, 1995–1999; 67%, 2010–2015). Risk of recurrence or death is lowest for small-vessel occlusion strokes and other ischemic causes (36% and 27% at 5 years, respectively). For cardioembolic and hemorrhagic index strokes around half of first recurrences are of the same type (54% and 51%, respectively). Over the whole study period a 54% increased risk of recurrence was observed among those who had atrial fibrillation before the index stroke (hazard ratio, 1.54 [1.09–2.17]). Conclusions: The rate of recurrence reduced until mid-2000s but has not changed over the last decade. The majority of cardioembolic or hemorrhagic strokes that have a recurrence are stroke of the same type indicating that the implementation of effective preventive strategies is still suboptimal in these stroke subtypes.
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Zhang, Q., Wang, C., Zheng, M., Li, Y., Li, J., Zhang, L., Shang, X., & Yan, C. (2015) · Cerebrovascular Diseases · doi:10.1159/000369778 · Cited by 11,533
Collaboration, A. T. (2002) · BMJ · doi:10.1136/bmj.324.7329.71 · Cited by 6,943
Isolated Hand Paresis: A Case Series
Alstadhaug, K. B., & Sjulstad, A. (2013) · Cerebrovascular Diseases Extra · doi:10.1159/000350708 · Cited by 4,058
Classification and natural history of clinically identifiable subtypes of cerebral infarction
Bamford, J., Sandercock, P., Dennis, M., Warlow, C., & Burn, J. (1991) · The Lancet · doi:10.1016/0140-6736(91)93206-o · Cited by 3,294
Kolominsky-Rabas, P. L., Weber, M., Gefeller, O., Neundoerfer, B., & Heuschmann, P. U. (2001) · Stroke · doi:10.1161/hs1201.100209 · Cited by 1,281
Early risk of recurrence by subtype of ischemic stroke in population-based incidence studies
Lovett, J. K., Coull, A. J., & Rothwell, P. M. (2004) · Neurology · doi:10.1212/01.wnl.0000110311.09970.83 · Cited by 741
Risk and Cumulative Risk of Stroke Recurrence: A Systematic Review and Meta-Analysis
Mohan, K. M., Wolfe, C. D. A., Rudd, A. G., Heuschmann, P. U., Kolominsky-Rabas, P. L., & Grieve, A. P. (2011) · Stroke · doi:10.1161/strokeaha.110.602615 · Cited by 683
Self-citationPuymirat, E., Simon, T., Cayla, G., Cottin, Y., Elbaz, M., Coste, P., Lemesle, G., Motreff, P., Popovic, B., Khalife, K., et al. (2017) · Circulation · doi:10.1161/circulationaha.117.030798 · Cited by 539
Anticoagulants for acute ischaemic stroke
Sandercock, P. A., Counsell, C., & Kamal, A. K. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000024.pub3 · Cited by 346
Cited by
Feigin, V. L., Owolabi, M. O., Feigin, V. L., Abd-Allah, F., Akinyemi, R. O., Bhattacharjee, N. V., Brainin, M., Cao, J., Caso, V., Dalton, B., et al. (2023) · The Lancet Neurology · doi:10.1016/s1474-4422(23)00277-6 · Cited by 804
Self-citationStrain, W. D., Frenkel, O., James, M. A., Leiter, L. A., Rasmussen, S., Rothwell, P. M., Sejersten Ripa, M., Truelsen, T. C., & Husain, M. (2022) · Stroke · doi:10.1161/strokeaha.121.037775 · Cited by 93
Moving Towards Equity With Digital Health Innovations for Stroke Care
Verma, A., Towfighi, A., Brown, A., Abhat, A., & Casillas, A. (2022) · Stroke · doi:10.1161/strokeaha.121.035307 · Cited by 65
Clancy, B., Bonevski, B., English, C., Baker, A. L., Turner, A., Magin, P., Pollack, M., Callister, R., & Guillaumier, A. (2022) · Journal of Medical Internet Research · doi:10.2196/33291 · Cited by 12
Metadata
- Authors
- Flach, C., Muruet, W., Wolfe, C. D. A., Bhalla, A., & Douiri, A.
- Venue
- Stroke
- Published
- 2020-08
- Volume
- 51
- Issue
- 8
- Pages
- 2435-2444
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W3042131576
- Cited by
- 336
- References
- 29
- FWCI
- 19.97
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Flach, C., Muruet, W., Wolfe, C. D. A., Bhalla, A., & Douiri, A. (2020). Risk and Secondary Prevention of Stroke Recurrence: A Population-Base Cohort Study. Stroke. https://doi.org/10.1161/strokeaha.120.028992
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