Synthesis and characterization of PLGA nanoparticles

Astete, Carlos E.; Sabliov, Cristina M.

doi:10.1163/156856206775997322

Cited by 776

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Synthesis and characterization of PLGA nanoparticles

Astete, Carlos E., Sabliov, Cristina M.·2006·Journal of Biomaterials Science, Polymer Edition

DOI 10.1163/156856206775997322

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Abstract

Poly(lactide-co-glycolide) (PLGA) nanoparticles of different physical characteristics (size, size distribution, morphology, zeta potential) can be synthesized by controlling the parameters specific to the synthesis method employed. The aim of this review is to clearly, quantitatively and comprehensively describe the top-down synthesis techniques available for PLGA nanoparticle formation, as well as the techniques commonly used for nanoparticle characterization. Many examples are discussed in detail to provide the reader with an extensive knowledge base on the important parameters specific to the synthesis method described and ways in which these parameters can be manipulated to control the nanoparticle physical characteristics.

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Authors: Astete, C. E., & Sabliov, C. M.
Venue: Journal of Biomaterials Science, Polymer Edition
Publisher: Informa UK Limited
Published: 2006-01
Volume: 17
Issue: 3
Pages: 247-289
ISSN: 0920-5063 (ISSN-L)
1568-5624
DOI: 10.1163/156856206775997322
OpenAlex: W2047368765
Cited by: 776
References: 8
FWCI: 9.43
Type: journal article
Language: en
Open access: closed

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Synthesis and characterization of PLGA nanoparticles

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