The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Immediate and Late Airway Response of Allergic Rhinitis Patients to Segmental Antigen Challenge: Characterization of Eosinophil and Mast Cell Mediators
Abstract
Segmental antigen bronchoprovocation was used to define the nature of the inflammatory process in allergic airway disease. Bronchoalveolar lavage fluid obtained from allergic rhinitis patients 12 min after segmental antigen instillation (immediate response) revealed a significant increase in histamine and tryptase, but no cellular response. Repeat segmental lavage 48 h later (late response) showed marked and significant increases in both low and normal density eosinophils as well as striking elevations of eosinophil granular protein levels (major basic protein, eosinophil-derived neurotoxin, eosinophil cationic protein, and eosinophil peroxidase). Leukotriene C4, but not tryptase, concentrations were also consistently elevated in late lavage samples. Further, the late lavage samples showed a significant increase in interleukin-5 concentrations that correlated with the presence of eosinophils and eosinophil granular proteins. Neither eosinophils nor soluble mediators of eosinophils increased when normal subjects were similarly challenged with antigen. These data suggest that eosinophils are attracted to the airway during the late-phase allergic reaction and that IL-5 may produce changes in airway eosinophil density and promote the release of granular proteins to cause airway injury.
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Citations
Cites
Eosinophilic Inflammation in Asthma
Bousquet, J., Chanez, P., Lacoste, J. Y., Barnéon, G., Ghavanian, N., Enander, I., Venge, P., Ahlstedt, S., Simony-Lafontaine, J., Godard, P., et al. (1990) · New England Journal of Medicine · doi:10.1056/nejm199010113231505 · Cited by 2,499
Standardization of bronchial inhalation challenge procedures
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Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions.
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Recombinant human interleukin 5 is a selective activator of human eosinophil function.
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Intercellular Adhesion Molecule-1 (ICAM-1) in the Pathogenesis of asthma
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Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis
Schwartz, L. B., Metcalfe, D. D., Miller, J. S., Earl, H., & Sullivan, T. (1987) · New England Journal of Medicine · doi:10.1056/nejm198706253162603 · Cited by 784
Self-citationInflammatory Mediators in Late Antigen-Induced Rhinitis
Naclerio, R. M., Proud, D., Togias, A. G., Adkinson, N. F., Meyers, D. A., Kagey-Sobotka, A., Plaut, M., Norman, P. S., & Lichtenstein, L. M. (1985) · New England Journal of Medicine · doi:10.1056/nejm198507113130201 · Cited by 692
Clutterbuck, E., Hirst, E., & Sanderson, C. (1989) · Blood · doi:10.1182/blood.v73.6.1504.1504 · Cited by 687
The eosinophil and the pathophysiology of asthma
Frigas, E., & Gleich, G. J. (1986) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(86)90341-6 · Cited by 602
Self-citationBurd, P. R., Rogers, H. W., Gordon, J. R., Martin, C. A., Jayaraman, S., Wilson, S. D., Dvorak, A. M., Galli, S. J., & Dorf, M. E. (1989) · The Journal of experimental medicine · doi:10.1084/jem.170.1.245 · Cited by 539
Cited by
Braunstahl, G.-J., Overbeek, S. E., KleinJan, A., Prins, J.-B., Hoogsteden, H. C., & Fokkens, W. J. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.113046 · Cited by 454
Segmental Bronchial Provocation Induces Nasal Inflammation in Allergic Rhinitis Patients
BRAUNSTAHL, G.-J., KLEINJAN, A., OVERBEEK, S. E., PRINS, J.-B., HOOGSTEDEN, H. C., & FOKKENS, W. J. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.6.9906121 · Cited by 399
Calhoun, W. J., Dick, E. C., Schwartz, L. B., & Busse, W. W. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117581 · Cited by 300
Self-citationDevelopment of a new, more sensitive immunoassay for human tryptase: use in systemic anaphylaxis
Schwartz, L. B., Bradford, T. R., Rouse, C., Irani, A.-M., Rasp, G., Van Der Zwan, J. K., & Van Der Linden, P.-W. G. (1994) · Journal of Clinical Immunology · doi:10.1007/bf01533368 · Cited by 263
Self-citationCorrigan, C. J., Haczku, A., Gemou-Engesaeth, V., Doi, S., Kikuchi, Y., Takatsu, K., Durham, S. R., & Kay, A. B. (1993) · American Review of Respiratory Disease · doi:10.1164/ajrccm/147.3.540 · Cited by 263
Metadata
- Authors
- Sedgwick, J. B., Calhoun, W. J., Gleich, G. J., Kita, H., Abrams, J. S., Schwartz, L. B., Volovitz, B., Ben-Yaakov, M., & Busse, W. W.
- Venue
- American Review of Respiratory Disease
- Publisher
- Oxford University Press (OUP)
- Published
- 1991-12
- Volume
- 144
- Issue
- 6
- Pages
- 1274-1281
- ISSN
- 0003-0805 (ISSN-L)
- OpenAlex
- W1963678276
- Cited by
- 275
- References
- 22
- FWCI
- 13.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sedgwick, J. B., Calhoun, W. J., Gleich, G. J., Kita, H., Abrams, J. S., Schwartz, L. B., Volovitz, B., Ben-Yaakov, M., & Busse, W. W. (1991). Immediate and Late Airway Response of Allergic Rhinitis Patients to Segmental Antigen Challenge: Characterization of Eosinophil and Mast Cell Mediators. American Review of Respiratory Disease. https://doi.org/10.1164/ajrccm/144.6.1274
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
