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Cited by 759Respiratory Support and MechanismsIntensive Care Unit Cognitive DisordersLong-Term Effects of COVID-19

The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.

Two-Year Cognitive, Emotional, and Quality-of-Life Outcomes in Acute Respiratory Distress Syndrome

Hopkins, Ramona O., Weaver, Lindell K., Collingridge, Dave, Parkinson, R. Bruce, Chan, Karen J., Orme, James F.·2005·American Journal of Respiratory and Critical Care Medicine
DOI 10.1164/rccm.200406-763oc
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Abstract

Acute respiratory distress syndrome (ARDS) has a high mortality and is associated with significant morbidity. Prior outcome studies have focused predominant on short-term outcomes (6–12 months). We assessed longitudinal neurocognitive, emotional, and quality of life in ARDS survivors at hospital discharge, and 1 and 2 years after hospital discharge using neuropsychologic tests and emotional and quality-of-life questionnaires. Neurocognitive sequelae occurred in 73% (54 of 74) of ARDS survivors at hospital discharge, 46% (30 of 66) at 1 year, and 47% (29 of 62) at 2 years. ARDS survivors report moderate to severe depression (16% and 23%) and anxiety (24% and 23%) at 1 and 2 years, respectively. The ARDS survivors had decreased quality of life, with the physical domains improving at 1 year, with no additional change at 2 years. Role emotional, pain, and general health did not change from hospital discharge to 2 years. Mental health improved during the first year and declined at 2 years. ARDS results in significant neurocognitive and emotional morbidity and decreased quality of life that persists at least 2 years after hospital discharge. ARDS can cause significant long-term, brain-related morbidity manifest by neurocognitive impairments and decreased quality of life.

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Metadata

Authors
Hopkins, R. O., Weaver, L. K., Collingridge, D., Parkinson, R. B., Chan, K. J., & Orme, J. F.
Affiliations
Brigham Young University (US)
ORCID
Collingridge, Dave
Venue
American Journal of Respiratory and Critical Care Medicine
Publisher
Oxford University Press (OUP)
Published
2005-02
Volume
171
Issue
4
Pages
340-347
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
DOI
10.1164/rccm.200406-763oc
OpenAlex
W2077201173
Cited by
759
References
66
Citations by year
2026: 14 · 2025: 25 · 2024: 36 · 2023: 25 · 2022: 41 · 2021: 74 · 2020: 57 · 2019: 38 · 2018: 32 · 2017: 32 · 2016: 38 · 2015: 38 · 2014: 29 · 2013: 34 · 2012: 38
FWCI
20.21
Type
journal article
Language
en
Open access
closed
Licence
academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations
  • American Journal of Respiratory and Critical Care Medicine (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Heart, Lung, and Blood Institute (HL-50513)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
  • Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
  • Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
Keywords
acute respiratory distress syndrome, ARDS survivors, neuropsychological sequelae, post-traumatic cognitive impairment, depression, anxiety, quality of life, long-term outcomes, brain injury
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Analysis of Variance, Cognition Disorders, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Neuropsychological Tests, Quality of Life, Surveys and Questionnaires, Respiratory Distress Syndrome, Time Factors, Comorbidity, Outcome Assessment, Health Care, Survivors, Sickness Impact Profile, Mood Disorders

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