The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
Two-Year Cognitive, Emotional, and Quality-of-Life Outcomes in Acute Respiratory Distress Syndrome
Abstract
Acute respiratory distress syndrome (ARDS) has a high mortality and is associated with significant morbidity. Prior outcome studies have focused predominant on short-term outcomes (6–12 months). We assessed longitudinal neurocognitive, emotional, and quality of life in ARDS survivors at hospital discharge, and 1 and 2 years after hospital discharge using neuropsychologic tests and emotional and quality-of-life questionnaires. Neurocognitive sequelae occurred in 73% (54 of 74) of ARDS survivors at hospital discharge, 46% (30 of 66) at 1 year, and 47% (29 of 62) at 2 years. ARDS survivors report moderate to severe depression (16% and 23%) and anxiety (24% and 23%) at 1 and 2 years, respectively. The ARDS survivors had decreased quality of life, with the physical domains improving at 1 year, with no additional change at 2 years. Role emotional, pain, and general health did not change from hospital discharge to 2 years. Mental health improved during the first year and declined at 2 years. ARDS results in significant neurocognitive and emotional morbidity and decreased quality of life that persists at least 2 years after hospital discharge. ARDS can cause significant long-term, brain-related morbidity manifest by neurocognitive impairments and decreased quality of life.
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“Persistent cognitive impairment was reported after a 2-year follow-up: roughly half of patients displayed signs of cognitive impairment [123].”
From Cognitive decline following acute viral infections: literature review and projections for post-COVID-19 (2022) · cites this paper as [123]
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Cited by
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Barr, J., Fraser, G. L., Puntillo, K., Ely, E. W., Gélinas, C., Dasta, J. F., Davidson, J. E., Devlin, J. W., Kress, J. P., Joffe, A. M., et al. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182783b72 · Cited by 3,896
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Functional Disability 5 Years after Acute Respiratory Distress Syndrome
Herridge, M. S., Tansey, C. M., Matte, A. L., TOMLINSON, G. A., Diaz-Granados, N., Cooper, A., Guest, C. B., Mazer, C. D., Mehta, S., Stewart, T. E., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1011802 · Cited by 2,892
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Self-citation
Metadata
- Authors
- Hopkins, R. O., Weaver, L. K., Collingridge, D., Parkinson, R. B., Chan, K. J., & Orme, J. F.
- Affiliations
- Brigham Young University (US)
- ORCID
- Collingridge, Dave
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-02
- Volume
- 171
- Issue
- 4
- Pages
- 340-347
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2077201173
- Cited by
- 759
- References
- 66
- Citations by year
- 2026: 14 · 2025: 25 · 2024: 36 · 2023: 25 · 2022: 41 · 2021: 74 · 2020: 57 · 2019: 38 · 2018: 32 · 2017: 32 · 2016: 38 · 2015: 38 · 2014: 29 · 2013: 34 · 2012: 38
- FWCI
- 20.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Respiratory and Critical Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Heart, Lung, and Blood Institute (HL-50513)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Keywords
- acute respiratory distress syndrome, ARDS survivors, neuropsychological sequelae, post-traumatic cognitive impairment, depression, anxiety, quality of life, long-term outcomes, brain injury
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Analysis of Variance, Cognition Disorders, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Neuropsychological Tests, Quality of Life, Surveys and Questionnaires, Respiratory Distress Syndrome, Time Factors, Comorbidity, Outcome Assessment, Health Care, Survivors, Sickness Impact Profile, Mood Disorders
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