The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
A Multicenter Trial of Prolonged Prone Ventilation in Severe Acute Respiratory Distress Syndrome
Abstract
RATIONALE: Ventilation in the prone position for about 7 h/d in patients with acute respiratory distress syndrome (ARDS), acute lung injury, or acute respiratory failure does not decrease mortality. Whether it is beneficial to administer prone ventilation early, and for longer periods of time, is unknown. METHODS: We enrolled 136 patients within 48 h of tracheal intubation for severe ARDS, 60 randomized to supine and 76 to prone ventilation. Guidelines were established for ventilator settings and weaning. The prone group was targeted to receive continuous prone ventilation treatment for 20 h/d. RESULTS: The intensive care unit mortality was 58% (35/60) in the patients ventilated supine and 43% (33/76) in the patients ventilated prone (p = 0.12). The latter had a higher simplified acute physiology score II at inclusion. Multivariate analysis showed that simplified acute physiology score II at inclusion (odds ratio [OR], 1.07; p < 0.001), number of days elapsed between ARDS diagnosis and inclusion (OR, 2.83; p < 0.001), and randomization to supine position (OR, 2.53; p = 0.03) were independent risk factors for mortality. A total of 718 turning procedures were done, and prone position was applied for a mean of 17 h/d for a mean of 10 d. A total of 28 complications were reported, and most were rapidly reversible. CONCLUSION: Prone ventilation is feasible and safe, and may reduce mortality in patients with severe ARDS when it is initiated early and applied for most of the day.
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(2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421801 · Cited by 12,941
Bernard, G. R., Artigas, A., Brigham, K. L., Carlet, J., Falke, K., Hudson, L., Lamy, M., Legall, J. R., Morris, A., & Spragg, R. (1994) · American journal of respiratory and critical care medicine · doi:10.1164/ajrccm.149.3.7509706 · Cited by 6,746
Effect of prone positioning on the survival of patients with acute respiratory failure.
Gattinoni, L., Tognoni, G., Pesenti, A., Taccone, P., Mascheroni, D., Labarta, V., Malacrida, R., Di Giulio, P., Fumagalli, R., Pelosi, P., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010043 · Cited by 1,271
BROCHARD, L., ROUDOT-THORAVAL, F., ROUPIE, E., DELCLAUX, C., CHASTRE, J., FERNANDEZ-MONDÉJAR, E., CLÉMENTI, E., MANCEBO, J., FACTOR, P., MATAMIS, D., et al. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.6.9801044 · Cited by 800
Self-citationMechanism by Which the Prone Position Improves Oxygenation in Acute Lung Injury
Lamm, W. J., Graham, M. M., & Albert, R. K. (1994) · American journal of respiratory and critical care medicine · doi:10.1164/ajrccm.150.1.8025748 · Cited by 486 · cited 2×
“Ventilator-associated pneumonia, n (%) 9 (15) 14 (18.”
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Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock
Dellinger, R. P., Levy, M. M., Rhodes, A., Annane, D., Gerlach, H., Opal, S. M., Sevransky, J. E., Sprung, C. L., Douglas, I. S., Jaeschke, R., et al. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e31827e83af · Cited by 9,694
Prone positioning in severe acute respiratory distress syndrome.
Guérin, C., Reignier, J., Richard, J.-C., Beuret, P., Gacouin, A., Boulain, T., Mercier, E., Badet, M., Mercat, A., Baudin, O., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1214103 · Cited by 4,040
Self-citationPeek, G. J., Mugford, M., Tiruvoipati, R., Wilson, A., Allen, E., Thalanany, M. M., Hibbert, C. L., Truesdale, A., Clemens, F., Cooper, N., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61069-2 · Cited by 3,395
Formal guidelines: Management of acute respiratory distress syndrome.
Papazian, L., Aubron, C., Brochard, L., Chiche, J.-D., Combes, A., Dreyfuss, D., Forel, J.-M., Guérin, C., Jaber, S., Mekontso-Dessap, A., et al. (2019) · Annals of Intensive Care · doi:10.1186/s13613-019-0540-9 · Cited by 761
Prone Position for Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis
Munshi, L., Del Sorbo, L., Adhikari, N. K. J., Hodgson, C. L., Wunsch, H., Meade, M. O., Uleryk, E., Mancebo, J., Pesenti, A., Ranieri, V. M., et al. (2017) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201704-343ot · Cited by 601
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Metadata
- Authors
- Mancebo, J., Fernández, R., Blanch, L., Rialp, G., Gordo, F., Ferrer, M., Rodríguez, F., Garro, P., Ricart, P., Vallverdú, I., Gich, I., Castaño, J., Saura, P., Domínguez, G., Bonet, A., & Albert, R. K.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-06-01
- Volume
- 173
- Issue
- 11
- Pages
- 1233-1239
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2104961217
- Cited by
- 565
- References
- 5
- FWCI
- 29.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- Mancebo, J., Fernández, R., Blanch, L., Rialp, G., Gordo, F., Ferrer, M., Rodríguez, F., Garro, P., Ricart, P., Vallverdú, I., Gich, I., Castaño, J., Saura, P., Domínguez, G., Bonet, A., & Albert, R. K. (2006). A Multicenter Trial of Prolonged Prone Ventilation in Severe Acute Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.200503-353oc
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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