The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Reference Ranges for Exhaled Nitric Oxide Derived from a Random Community Survey of Adults
Abstract
RATIONALE: Measurement of the fraction of nitric oxide in exhaled breath (Fe(NO)) has been proposed as a noninvasive marker of airway inflammation. Before the widespread use of this test, there is a need to develop reference ranges to allow clinicians to interpret Fe(NO) measurements. OBJECTIVES: To derive reference ranges for Fe(NO) and to determine which factors in health and disease influence Fe(NO) levels. METHODS: Subjects aged between 25 and 75 years were drawn from a random sample of the predominantly white population of Wellington, New Zealand. MEASUREMENTS AND MAIN RESULTS: Fe(NO) was measured using an online nitric oxide monitor in accordance with international guidelines. A detailed respiratory questionnaire and pulmonary function tests were performed. The geometric mean Fe(NO) was 17.9 parts per billion (ppb) with a 90% confidence interval for an individual prediction (reference range) for normal subjects of 7.8 to 41.1 ppb. Sex, atopy, and smoking status significantly affected Fe(NO) levels, and several reference ranges are presented adjusting for these factors. Asthma and allergic rhinitis were associated with higher Fe(NO). Measurement of Fe(NO) had poor discriminant ability to identify steroid-naive subjects with asthma. CONCLUSIONS: The reference ranges presented may be used to assist in the interpretation of Fe(NO) measurements in white adults.
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(2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200406-710st · Cited by 3,203
Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans
Gustafsson, L. E., Leone, A. M., Persson, M. G., Wiklund, N. P., & Moncada, S. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)91268-h · Cited by 964
Nitric oxide in health and disease of the respiratory system
Ricciardolo, F. L. M., Sterk, P. J., Gaston, B., & Folkerts, G. (2004) · Physiological Reviews · doi:10.1152/physrev.00034.2003 · Cited by 903
Cited by
Dweik, R. A., Boggs, P. B., Erzurum, S. C., Irvin, C. G., Leigh, M. W., Lundberg, J. O., Olin, A.-C., Plummer, A. L., & Taylor, D. R. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.9120-11st · Cited by 2,539
Reddel, H. K., Taylor, D. R., Bateman, E. D., Boulet, L.-P., Boushey, H. A., Busse, W. W., Casale, T. B., Chanez, P., Enright, P. L., Gibson, P. G., et al. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200801-060st · Cited by 1,918
Szefler, S. J., Wenzel, S., Brown, R., Erzurum, S. C., Fahy, J. V., Hamilton, R. G., Hunt, J. F., Kita, H., Liu, A. H., Panettieri, R. A., et al. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.12.979 · Cited by 395
Weschler, C. J., & Carslaw, N. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.7b06387 · Cited by 293
Microgravity decreases and hypergravity increases exhaled nitric oxide
Karlsson, L. L., Kerckx, Y., Gustafsson, L. E., Hemmingsson, T. E., & Linnarsson, D. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.91081.2008 · Cited by 16
Metadata
- Authors
- Travers, J., Marsh, S., Aldington, S., Williams, M., Shirtcliffe, P., Pritchard, A., Weatherall, M., & Beasley, R.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-08-01
- Volume
- 176
- Issue
- 3
- Pages
- 238-242
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2157650286
- Cited by
- 222
- References
- 3
- FWCI
- 13.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- Travers, J., Marsh, S., Aldington, S., Williams, M., Shirtcliffe, P., Pritchard, A., Weatherall, M., & Beasley, R. (2007). Reference Ranges for Exhaled Nitric Oxide Derived from a Random Community Survey of Adults. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.200609-1346oc
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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