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Practice Recommendations in the Diagnosis, Management, and Prevention of Carbon Monoxide Poisoning
Abstract
Carbon monoxide (CO) poisoning is common in modern society, resulting in significant morbidity and mortality in the United States annually. Over the past two decades, sufficient information has been published about carbon monoxide poisoning in the medical literature to draw firm conclusions about many aspects of the pathophysiology, diagnosis, and clinical management of the syndrome, along with evidence-based recommendations for optimal clinical practice. This article provides clinical practice guidance to the pulmonary and critical care community regarding the diagnosis, management, and prevention of acute CO poisoning. The article represents the consensus opinion of four recognized content experts in the field. Supporting data were drawn from the published, peer-reviewed literature on CO poisoning, placing emphasis on selecting studies that most closely mirror clinical practice.
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“CO poisoning includes both, tissue hypoxia and direct cellular changes through various mechanisms, e.g., mitochondrial inhibition, free radical generation, apoptosis, immune-mediated injury, inflammatory effects (Hampson et al., 2012; Rose et al., 2017).”
From Low-dose carbon monoxide inhalation to increase total hemoglobin mass and endurance performance: scientific evidence and implications (2024) · cites this paper as Hampson et al., 2012
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Cited by
Gatterer, H., Dünnwald, T., Woyke, S., Faulhaber, M., Schumacher, Y. O., & Schobersberger, W. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1490205 · Cited by 13
Metadata
- Authors
- Hampson, N. B., Piantadosi, C. A., Thom, S. R., & Weaver, L. K.
- Affiliations
- Virginia Mason Medical Center, Seattle, Washington
- Duke University Medical Center, Durham, North Carolina
- University of Pennsylvania Medical Center, Philadelphia, Pennsylvania; and
- Intermountain Medical Center, Salt Lake City, Utah
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-12-01
- Volume
- 186
- Issue
- 11
- Pages
- 1095-1101
- ISSN
- 1073-449X
- 1535-4970
- Cited by
- 331
- References
- 0
- Language
- en
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