Randomized trial of communication facilitators to reduce family distress and intensity of end-of-life care
Open accessAbstract
Rationale Communication with family of critically ill patients is often poor and associated with family distress. Objectives To determine if an intensive care unit (ICU) communication facilitator reduces family distress and intensity of end-of-life care. Methods We conducted a randomized trial at two hospitals. Eligible patients had a predicted mortality greater than or equal to 30% and a surrogate decision maker. Facilitators supported communication between clinicians and families, adapted communication to family needs, and mediated conflict. Measurements and main results Outcomes included depression, anxiety, and post-traumatic stress disorder (PTSD) among family 3 and 6 months after ICU and resource use. We identified 488 eligible patients and randomized 168. Of 352 eligible family members, 268 participated (76%). Family follow-up at 3 and 6 months ranged from 42 to 47%. The intervention was associated with decreased depressive symptoms at 6 months (P = 0.017), but there were no significant differences in psychological symptoms at 3 months or anxiety or PTSD at 6 months. The intervention was not associated with ICU mortality (25% control vs. 21% intervention; P = 0.615) but decreased ICU costs among all patients (per patient: $75,850 control, $51,060 intervention; P = 0.042) and particularly among decedents ($98,220 control, $22,690 intervention; P = 0.028). Among decedents, the intervention reduced ICU and hospital length of stay (28.5 vs. 7.7 d and 31.8 vs. 8.0 d, respec…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Family support interventions may help reduce psychological impacts on family members, as suggested by four systematic reviews and two recent studies.
“Family support interventions may help to reduce these psychological impacts, as suggested by four systematic reviews, 37,71,72,83 and two recent studies. 84,85”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [85]
Cites
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910 · see citing works
Kroenke, K., Spitzer, R. L., Williams, J. B. W., & Löwe, B. (2010) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2010.03.006 · Cited by 4,057 · see citing works
A Controlled Trial to Improve Care for Seriously III Hospitalized Patients
Connors, A. F. (1995) · JAMA · doi:10.1001/jama.274.20.1591 · Cited by 3,416 · see citing works
Generalist plus Specialist Palliative Care — Creating a More Sustainable Model
Quill, T. E., & Abernethy, A. P. (2013) · New England Journal of Medicine · doi:10.1056/nejmp1215620 · Cited by 1,464 · see citing works
Monitoring Depression Treatment Outcomes With the Patient Health Questionnaire-9
L??we, B., Un??tzer, J., Callahan, C. M., Perkins, A. J., & Kroenke, K. (2004) · Medical Care · doi:10.1097/00005650-200412000-00006 · Cited by 1,354 · see citing works
A communication strategy and brochure for relatives of patients dying in the ICU.
Lautrette, A., Darmon, M., Megarbane, B., Joly, L. M., Chevret, S., Adrie, C., Barnoud, D., Bleichner, G., Bruel, C., Choukroun, G., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa063446 · Cited by 1,279 · see citing works
Self-citationUse of intensive care at the end of life in the United States: An epidemiologic study*
Angus, D. C., Barnato, A. E., Linde‐Zwirble, W. T., Weissfeld, L. A., Watson, R. S., Rickert, T., & Rubenfeld, G. D. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000114816.62331.08 · Cited by 1,157 · see citing works
LOWE, B. (2004) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00237-9 · Cited by 1,060 · see citing works
Enders, C. K. (2001) · Psychological Methods · doi:10.1037/1082-989x.6.4.352 · Cited by 942 · see citing works
Schneiderman, L. J., Gilmer, T., Teetzel, H. D., Dugan, D. O., Blustein, J., Cranford, R., Briggs, K. B., Komatsu, G. I., Goodman-Crews, P., Cohn, F., et al. (2003) · JAMA · doi:10.1001/jama.290.9.1166 · Cited by 661 · see citing works
An intensive communication intervention for the critically ill
Lilly, C. M., Meo, D. L. D., Sonna, L. A., Haley, K. J., Massaro, A. F., Wallace, R. F., & Cody, S. (2000) · The American Journal of Medicine · doi:10.1016/s0002-9343(00)00524-6 · Cited by 509 · see citing works
Ethics and end-of-life care for adults in the intensive care unit
Curtis, J. R., & Vincent, J. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60143-2 · Cited by 362 · see citing works
Self-citationImpact of a Proactive Approach to Improve End-of-Life Care in a Medical ICU
Campbell, M., & Guzmán, J. A. (2003) · CHEST Journal · doi:10.1378/chest.123.1.266 · Cited by 353 · see citing works
Heyland, D. K., Hopman, W. M., Coo, H., Tranmer, J. E., & McColl, M. A. (2000) · Critical Care Medicine · doi:10.1097/00003246-200011000-00006 · Cited by 345 · see citing works
Bota, D. P., Mélot, C., Ferreira, F. L., Ba, V. N., & Vincent, J. (2002) · Intensive Care Medicine · doi:10.1007/s00134-002-1491-3 · Cited by 280 · see citing works
Ell, K., Xie, B., Quon, B., Quinn, D. I., Dwight‐Johnson, M., & Lee, P.-J. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2008.16.6371 · Cited by 270 · see citing works
Curtis, J. R., Nielsen, E. L., Treece, P. D., Downey, L., Dotolo, D., Shannon, S. E., Back, A. L., Rubenfeld, G. D., & Engelberg, R. A. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201006-1004oc · Cited by 269 · see citing works
Self-citationImpact of ethics consultations in the intensive care setting: A randomized, controlled trial.
Schneiderman, L. J., Gilmer, T., & Teetzel, H. D. (2000) · Critical Care Medicine · doi:10.1097/00003246-200012000-00033 · Cited by 265 · see citing works
Randomized, Controlled Trials of Interventions to Improve Communication in Intensive Care
Scheunemann, L. P., McDevitt, M., Carson, S. S., & Hanson, L. C. (2010) · CHEST Journal · doi:10.1378/chest.10-0595 · Cited by 258 · see citing works
Dowdy, M. D., Robertson, C., & Bander, J. A. (1998) · Critical Care Medicine · doi:10.1097/00003246-199802000-00020 · Cited by 237 · see citing works
Integrating Palliative and Critical Care: Evaluation of a Quality-Improvement Intervention
Curtis, J. R., Treece, P. D., Nielsen, E. L., Downey, L., Shannon, S. E., Braungardt, T., Owens, D. A., Steinberg, K. P., & Engelberg, R. A. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200802-272oc · Cited by 226 · see citing works
Self-citationEll, K., Katon, W. J., Xie, B., Lee, P.-J., Kapetanovic, S., Guterman, J. J., & Chou, C.-P. (2010) · Diabetes Care · doi:10.2337/dc09-1711 · Cited by 222 · see citing works
Richards, D. A., & Borglin, G. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.03.024 · Cited by 217 · see citing works
Kahn, J. M., Rubenfeld, G. D., Rohrbach, J. I., & Fuchs, B. D. (2008) · Medical Care · doi:10.1097/mlr.0b013e31817d9342 · Cited by 202 · see citing works
Intensive communication: Four-year follow-up from a clinical practice study
Lilly, C. M., Sonna, L. A., Haley, K. J., & Massaro, A. F. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000065279.77449.b4 · Cited by 197 · see citing works
A method for assessing the clinical performance and cost-effectiveness of intensive care units
Rapoport, J., Teres, D., LEMESHOW, S., & Gehlbach, S. H. (1994) · Critical Care Medicine · doi:10.1097/00003246-199409000-00006 · Cited by 191 · see citing works
Campbell, M., & Guzmán, J. A. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000138560.56577.88 · Cited by 172 · see citing works
Responsiveness of the PHQ-9 to Psychopharmacological Depression Treatment
Löwe, B., Karapanagiotou‐Schenkel, I., Carney, C. P., & Göbel, C. (2005) · Psychosomatics · doi:10.1176/appi.psy.47.1.62 · Cited by 132 · see citing works
Effectiveness Trial of an Intensive Communication Structure for Families of Long-Stay ICU Patients
Daly, B. J., Douglas, S. L., O’Toole, E. E., Gordon, N. H., Hejal, R. B., Peerless, J. R., Rowbottom, J. R., Garland, A., Lilly, C. M., Wiencek, C. A., et al. (2010) · CHEST Journal · doi:10.1378/chest.10-0292 · Cited by 124 · see citing works
Use of the Sequential Organ Failure Assessment score as a severity score
Amaral, A. C. K.-B., Andrade, F. M., Moreno, R. P., Artigas, A., Cantraine, F. R. L., & Vincent, J. (2005) · Intensive Care Medicine · doi:10.1007/s00134-004-2528-6 · Cited by 100 · see citing works
Curtis, J. R., Ciechanowski, P. S., Downey, L., Gold, J., Nielsen, E. L., Shannon, S. E., Treece, P. D., Young, J. P., & Engelberg, R. A. (2012) · Contemporary Clinical Trials · doi:10.1016/j.cct.2012.06.010 · Cited by 88 · see citing works
Self-citationExplaining Variability of Cost Using a Severity-of-lllness Measure for ICU Patients
Rapoport, J., Teres, D., Lemeshow, S. A., Avrunin, J. S., & Haber, R. (1990) · Medical Care · doi:10.1097/00005650-199004000-00005 · Cited by 77 · see citing works
Pediatric Palliative Care and Inpatient Hospital Costs: A Longitudinal Cohort Study
Smith, A., Andrews, S., Bratton, S. L., Sheetz, J., Feudtner, C., Zhong, W., & Maloney, C. G. (2015) · PEDIATRICS · doi:10.1542/peds.2014-3161 · Cited by 44 · see citing works
Long-term sequelae of critical illness: memories and health-related quality of life.
Hough, C. L., & Curtis, J. R. (2005) · Critical Care · doi:10.1186/cc3483 · Cited by 36 · see citing works
Self-citationEthics Consultations in the Intensive Care Setting
Schneiderman, L. J., Gilmer, T., & Teetzel, H. D. (2002) · Critical Care Medicine · doi:10.1097/00003246-200202000-00041 · Cited by 9 · see citing works
Flagged first, then by citations
1 of the 36 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Guidelines for Family-Centered Care in the Neonatal, Pediatric, and Adult ICU
Davidson, J. E., Aslakson, R. A., Long, A. C., Puntillo, K. A., Kross, E. K., Hart, J., Cox, C. E., Wunsch, H., Wickline, M. A., Nunnally, M. E., et al. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002169 · Cited by 1,540 · see citing works
Self-citationPost‐intensive care syndrome: its pathophysiology, prevention, and future directions
Inoue, S., Hatakeyama, J., Kondo, Y., Hifumi, T., Sakuramoto, H., Kawasaki, T., Taito, S., Nakamura, K., Unoki, T., Kawai, Y., et al. (2019) · Acute Medicine & Surgery · doi:10.1002/ams2.415 · Cited by 615 · see citing works
A randomized trial of a family-support intervention in intensive care units
White, D. B., Angus, D. C., Shields, A.-M., Buddadhumaruk, P., Pidro, C., Paner, C., Chaitin, E., Chang, C.-C. H., Pike, F., Weissfeld, L., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1802637 · Cited by 524 · see citing works
Outcomes after Critical Illness
Herridge, M. S., & Azoulay, É. (2023) · New England Journal of Medicine · doi:10.1056/nejmra2104669 · Cited by 378 · see citing works
Carson, S. S., Cox, C. E., Wallenstein, S., Hanson, L. C., Danis, M., Tulsky, J. A., Chai, E., & Nelson, J. E. (2016) · JAMA · doi:10.1001/jama.2016.8474 · Cited by 352 · see citing works
Goldfarb, M., Bibas, L., Bartlett, V. L., Jones, H., & Khan, N. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002624 · Cited by 306 · see citing works
Changes in End-of-Life Practices in European Intensive Care Units From 1999 to 2016
Sprung, C. L., Ricou, B., Hartog, C. S., Maia, P., Mentzelopoulos, S. D., Weiß, M., Levin, P. D., Galarza, L., de la Guardia, V., Schefold, J. C., et al. (2019) · JAMA · doi:10.1001/jama.2019.14608 · Cited by 259 · see citing works
European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions
Mentzelopoulos, S. D., Couper, K., Voorde, P. V. D., Druwé, P., Blom, M., Perkins, G. D., Lulic, I., Djakow, J., Raffay, V., Lilja, G., et al. (2021) · Resuscitation · doi:10.1016/j.resuscitation.2021.02.017 · Cited by 246 · see citing works
Early psychological intervention following recent trauma: a systematic review and meta-analysis
Roberts, N. P., Kitchiner, N. J., Kenardy, J., Lewis, C. E., & Bisson, J. I. (2019) · European Journal of Psychotraumatology · doi:10.1080/20008198.2019.1695486 · Cited by 200 · see citing works
Johnson, C. C., Suchyta, M. R., Darowski, E. S., Collar, E. M., Kiehl, A. L., Van, J., Jackson, J. C., & Hopkins, R. O. (2019) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201808-540sr · Cited by 193 · see citing works
Early palliative care consultation in the medical ICU: A cluster randomized crossover trial.
Ma, J., Chi, S., Buettner, B., Pollard, K., Muir, M., Kolekar, C., Al-Hammadi, N., Chen, L., Kollef, M., & Dans, M. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000004016 · Cited by 166 · see citing works
Recovery after critical illness: putting the puzzle together—a consensus of 29
Azoulay, É., Vincent, J., Angus, D. C., Arabi, Y. M., Brochard, L. J., Brett, S. J., Citerio, G., Cook, D. J., Curtis, J. R., dos Santos, C. C., et al. (2017) · Critical Care · doi:10.1186/s13054-017-1887-7 · Cited by 165 · see citing works
Self-citationGarrouste-Orgeas, M., Flahault, C., Vinatier, I., Rigaud, J., Thieulot-Rolin, N., Mercier, E., Rouget, A., Grand, H., Lesieur, O., Tamion, F., et al. (2019) · JAMA · doi:10.1001/jama.2019.9058 · Cited by 165 · see citing works
Famirea Study Group, Kentish-Barnes, N., Chevret, S., Champigneulle, B., Thirion, M., Souppart, V., Gilbert, M., Lesieur, O., Renault, A., Garrouste-Orgeas, M., et al. (2017) · Intensive Care Medicine · doi:10.1007/s00134-016-4669-9 · Cited by 143 · see citing works
Society of Critical Care Medicine Guidelines on Family-Centered Care for Adult ICUs: 2024
Hwang, D. Y., Oczkowski, S. J. W., Lewis, K. A., Birriel, B., Downar, J., Farrier, C. E., Fiest, K. M., Gerritsen, R. T., Hart, J. L., Hartog, C. S., et al. (2025) · Critical Care Medicine · doi:10.1097/ccm.0000000000006549 · Cited by 140 · see citing works
Interventions in Post-Intensive Care Syndrome-Family: A Systematic Literature Review
Zante, B., Camenisch, S. A., & Schefold, J. C. (2020) · Critical Care Medicine · doi:10.1097/ccm.0000000000004450 · Cited by 136 · see citing works
Kentish‐Barnes, N., Chevret, S., Valade, S., Jaber, S., Kerhuel, L., Guisset, O., Martin, M., Mazaud, A., Papazian, L., Argaud, L., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(21)02176-0 · Cited by 134 · see citing works
Chang, D., Neville, T. H., Parrish, J., Ewing, L., Rico, C. C., Jara, L., Sim, D., Tseng, C., van Zyl, C., Storms, A. D., et al. (2021) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2021.1000 · Cited by 125 · see citing works
Palliative care interventions in intensive care unit patients
Metaxa, V., Anagnostou, D., Vlachos, S., Arulkumaran, N., Bensemmane, S., van Dusseldorp, I., Aslakson, R. A., Davidson, J. E., Gerritsen, R. T., Hartog, C. S., et al. (2021) · Intensive Care Medicine · doi:10.1007/s00134-021-06544-6 · Cited by 119 · see citing works
Self-citationDionne-Odom, J. N., Ejem, D., Wells, R., Barnato, A. E., Taylor, R. A., Rocque, G. B., Turkman, Y. E., Kenny, M., Ivankova, N. V., Bakitas, M. A., et al. (2019) · PLOS ONE · doi:10.1371/journal.pone.0212967 · Cited by 111 · see citing works
How Often Is End-of-Life Care in the United States Inconsistent with Patients' Goals of Care?
Khandelwal, N., Curtis, J. R., Freedman, V. A., Kasper, J. D., Gozalo, P. L., Engelberg, R. A., & Teno, J. M. (2017) · Journal of Palliative Medicine · doi:10.1089/jpm.2017.0065 · Cited by 104 · see citing works
Self-citationYamaguchi, T., Maeda, I., Hatano, Y., Mori, M., Shima, Y., Tsuneto, S., Kizawa, Y., Morita, T., Yamaguchi, T., Aoyama, M., et al. (2017) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2017.03.008 · Cited by 102 · see citing works
Überversorgung in der Intensivmedizin: erkennen, benennen, vermeiden
Michalsen, A., Neitzke, G., Dutzmann, J., Rogge, A., Seidlein, A., Jöbges, S., Burchardi, H., Hartog, C. S., Nauck, F., Salomon, F., et al. (2021) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-021-00794-4 · Cited by 99 · see citing works
Patient-Centered and Family-Centered Care in the Intensive Care Unit
Secunda, K. E., & Kruser, J. M. (2022) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2022.05.008 · Cited by 111 · see citing works
Postintensive care syndrome family: A comprehensive review
Shirasaki, K., Hifumi, T., Nakanishi, N., Nosaka, N., Miyamoto, K., Komachi, M. H., Haruna, J., Inoue, S., & Otani, N. (2024) · Acute Medicine & Surgery · doi:10.1002/ams2.939 · Cited by 105 · see citing works
Bibas, L., Peretz-Larochelle, M., Adhikari, N. K. J., Goldfarb, M., Luk, A. C., Englesakis, M. F., Detsky, M. E., & Lawler, P. R. (2019) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.7229 · Cited by 91 · see citing works
Effect of ICU strain on timing of limitations in life-sustaining therapy and on death
Hua, M. S., Halpern, S. D., Gabler, N. B., & Wunsch, H. (2016) · Intensive Care Medicine · doi:10.1007/s00134-016-4240-8 · Cited by 87 · see citing works
Preventing the onset of post traumatic stress disorder
Bisson, J. I., Wright, L. A., Jones, K. A., Lewis, C., Phelps, A. J., Sijbrandij, M., Varker, T., & Roberts, N. P. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.102004 · Cited by 85 · see citing works
Lee, R. Y., Brumback, L. C., Lober, W. B., Sibley, J., Nielsen, E. L., Treece, P. D., Kross, E. K., Loggers, E. T., Fausto, J. A., Lindvall, C. J., et al. (2020) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2020.08.024 · Cited by 81 · see citing works
Self-citationLee, H. W., Park, Y., Jang, E. J., & Lee, Y. J. (2019) · Intensive Care Medicine · doi:10.1007/s00134-019-05681-3 · Cited by 74 · see citing works
Bagshaw, S. M., Opgenorth, D. L., Potestio, M. L., Hastings, S. E., Hepp, S. L., Gilfoyle, E., McKinlay, D., Boucher, P. E., Meier, M., Leigh, J. P., et al. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000002093 · Cited by 70 · see citing works
Relatives' perception of stressors and psychological outcomes – Results from a survey study
Matt, B., Schwarzkopf, D., Reinhart, K., König, C. M., & Hartog, C. S. (2017) · Journal of Critical Care · doi:10.1016/j.jcrc.2017.02.036 · Cited by 71 · see citing works
Amass, T. H., Villa, G., O’Mahony, S., Badger, J. M., McFadden, R., Walsh, T. P., Caine, T., McGuirl, D., Palmisciano, A. J., Yeow, M.-E., et al. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000004113 · Cited by 71 · see citing works
Self-citationTen areas for ICU clinicians to be aware of to help retain nurses in the ICU
Vincent, J., Boulanger, C., van Mol, M. M. C., Hawryluck, L., & Azoulay, É. (2022) · Critical Care · doi:10.1186/s13054-022-04182-y · Cited by 69 · see citing works
Wendlandt, B., Ceppe, A., Choudhury, S., Cox, C. E., Hanson, L. C., Danis, M., Tulsky, J. A., Nelson, J. E., & Carson, S. S. (2019) · Intensive Care Medicine · doi:10.1007/s00134-019-05550-z · Cited by 68 · see citing works
The Family Navigator: A Pilot Intervention to Support Intensive Care Unit Family Surrogates
Torke, A. M., Wocial, L. D., Johns, S. A., Sachs, G. A., Callahan, C. M., Bosslet, G. T., Slaven, J. E., Perkins, S. M., Hickman, S. E., Montz, K., et al. (2016) · American Journal of Critical Care · doi:10.4037/ajcc2016730 · Cited by 67 · see citing works
Roberts, N. P., Kitchiner, N., Kenardy, J. A., Robertson, L., Lewis, C., & Bisson, J. I. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006869.pub3 · Cited by 71 · see citing works
Naef, R., von Felten, S., Petry, H., Ernst, J., & Massarotto, P. (2021) · Australian Critical Care · doi:10.1016/j.aucc.2020.10.014 · Cited by 63 · see citing works
Wendlandt, B., Kime, M., & Carson, S. S. (2021) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2021.103123 · Cited by 61 · see citing works
Amass, T., Van Scoy, L. J., Hua, M., Ambler, M., Armstrong, P., Baldwin, M. R., Bernacki, R., Burhani, M. D., Chiurco, J., Cooper, Z., et al. (2022) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2022.1118 · Cited by 61 · see citing works
Self-citationAslakson, R. A., Reinke, L. F., Cox, C. E., Kross, E. K., Benzo, R. P., & Curtis, J. R. (2017) · Journal of Palliative Medicine · doi:10.1089/jpm.2016.0567 · Cited by 67 · see citing works
Self-citationPalliative Care and End-of-Life Considerations for the Frail Patient
Crooms, R. C., & Gelfman, L. P. (2020) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000004763 · Cited by 59 · see citing works
Zhang, Y., Zhang, X., Zhang, L., & Guo, C. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.00446 · Cited by 63 · see citing works
Improving the intensive care experience from the perspectives of different stakeholders
Latour, J. M., Kentish‐Barnes, N., Jacques, T. C., Wysocki, M., Azoulay, É., & Metaxa, V. (2022) · Critical Care · doi:10.1186/s13054-022-04094-x · Cited by 58 · see citing works
Gerritsen, R. T., Koopmans, M., Hofhuis, J. G. M., Curtis, J. R., Jensen, H. I., Zijlstra, J. G., Engelberg, R. A., & Spronk, P. E. (2016) · CHEST Journal · doi:10.1016/j.chest.2016.09.003 · Cited by 53 · see citing works
Self-citationRyan, R. E., Connolly, M., Bradford, N., Henderson, S., Herbert, A., Schonfeld, L., Young, J., Bothroyd, J. I., & Henderson, A. J. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013116.pub2 · Cited by 59 · see citing works
Self-citationDuong, J., Wang, G., Lean, G., Slobod, D., & Goldfarb, M. (2024) · Journal of critical care · doi:10.1016/j.jcrc.2024.154829 · Cited by 48 · see citing works
Naef, R., Massarotto, P., & Petry, H. (2020) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2020.102916 · Cited by 49 · see citing works
Hochendoner, S. J., Amass, T. H., Curtis, J. R., Witt, P. D., Weng, X., Toyobo, O., Lipnick, D., Armstrong, P., Cruse, M. H., Rea, O., et al. (2021) · Annals of the American Thoracic Society · doi:10.1513/annalsats.202105-629oc · Cited by 47 · see citing works
Self-citationInformation or education interventions for adult intensive care unit (ICU) patients and their carers
Lewis, S. R., Pritchard, M., Schofield-Robinson, O. J., Evans, D. J., Alderson, P., & Smith, A. F. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012471.pub2 · Cited by 46 · see citing works
Primary palliative care recommendations for critical care clinicians
Ito, K., George, N. R., Wilson, J. G., Bowman, J. K., Aaronson, E. L., & Ouchi, K. (2022) · Journal of Intensive Care · doi:10.1186/s40560-022-00612-9 · Cited by 50 · see citing works
How to communicate with families living in complete isolation
Mistraletti, G., Gristina, G. R., Mascarin, S., Iacobone, E., Giubbilo, I., Bonfanti, S., Fiocca, F., Fullin, G., Fuselli, E., Bocci, M. G., et al. (2020) · BMJ Supportive & Palliative Care · doi:10.1136/bmjspcare-2020-002633 · Cited by 45 · see citing works
Lee, R. Y., Kross, E. K., Downey, L., Paul, S. R., Heywood, J., Nielsen, E. L., Okimoto, K., Brumback, L. C., Merel, S. E., Engelberg, R. A., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.5088 · Cited by 44 · see citing works
Self-citationQuestions to improve family–staff communication in the ICU: a randomized controlled trial
Azoulay, É., Forel, J.-M., Vinatier, I., Truillet, R., Renault, A., Valade, S., Jaber, S., Durand-Gasselin, J., Schwebel, C., Georges, H., et al. (2018) · Intensive Care Medicine · doi:10.1007/s00134-018-5423-2 · Cited by 44 · see citing works
Self-citationXyrichis, A., Fletcher, S., Philippou, J., Brearley, S. A., Terblanche, M., & Rafferty, A. M. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-042556 · Cited by 43 · see citing works
Kentish‐Barnes, N., Azoulay, É., Reignier, J., Cariou, A., Lafarge, A., Huet, O., Gargadennec, T., Renault, A., Souppart, V., Clavier, P., et al. (2024) · Intensive Care Medicine · doi:10.1007/s00134-024-07390-y · Cited by 41 · see citing works
Self-citationWang, G., Antel, R., & Goldfarb, M. (2023) · Journal of Intensive Care Medicine · doi:10.1177/08850666231173868 · Cited by 38 · see citing works
Wendlandt, B., Ceppe, A., Choudhury, S., Nelson, J. E., Cox, C. E., Hanson, L. C., Danis, M., Tulsky, J. A., & Carson, S. S. (2018) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201806-420oc · Cited by 38 · see citing works
Selecting and evaluating decision-making strategies in the intensive care unit: A systematic review
Kerckhoffs, M. C., Kant, M., van Delden, J. J. M., Hooft, L., Kesecioğlu, J., & van Dijk, D. (2019) · Journal of Critical Care · doi:10.1016/j.jcrc.2019.01.029 · Cited by 39 · see citing works
Naef, R., Filipovic, M., Jeitziner, M., von Felten, S., Safford, J., Riguzzi, M., & Rufer, M. (2022) · Trials · doi:10.1186/s13063-022-06454-y · Cited by 41 · see citing works
Cox, C. E., & Curtis, J. R. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201508-1628cp · Cited by 36 · see citing works
Self-citationTorke, A. M., Callahan, C. M., Sachs, G. A., Wocial, L. D., Helft, P. R., Monahan, P. O., Slaven, J. E., Montz, K., Burke, E. S., & Inger, L. (2017) · Journal of General Internal Medicine · doi:10.1007/s11606-017-4222-8 · Cited by 37 · see citing works
Dying Patient and Family Contributions to Nurse Distress in the ICU
Lief, L., Berlin, D., Maciejewski, R. C., Westman, L., Su, A., Cooper, Z. R., Ouyang, D. J., Epping, G., Derry, H. M., Russell, D., et al. (2018) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201804-284oc · Cited by 37 · see citing works
Nurse-Led Family Support Intervention for Families of Critically Ill Patients
Naef, R., Jeitziner, M., Riguzzi, M., von Felten, S., Verweij, L., Rufer, M., Safford, J., Sutter, S., Bergmann-Kipfer, B., Betschart, U., et al. (2025) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2025.3406 · Cited by 38 · see citing works
Cox, C. E., Ashana, D. C., Haines, K., Casarett, D., Olsen, M. K., Parish, A., O’Keefe, Y. A., Al-Hegelan, M. S., Harrison, R. W., Naglee, C., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.44093 · Cited by 36 · see citing works
Sanderson, E. A. M., Humphreys, S. K., Walker, F., Harris, D., Carduff, E., McPeake, J. M., Boyd, K. J., Pattison, N. A., & Lone, N. (2022) · PLoS ONE · doi:10.1371/journal.pone.0264971 · Cited by 36 · see citing works
Ethik der Reanimation und Entscheidungen am Lebensende
Bossaert, L. L., Perkins, G. D., Askitopoulou, H., Raffay, V. I., Greif, R., Haywood, K. L., Mentzelopoulos, S. D., Nolan, J. P., de Voorde, P. V., & Xanthos, T. T. (2015) · Notfall + Rettungsmedizin · doi:10.1007/s10049-015-0083-z · Cited by 41 · see citing works
Kalocsai, C., Amaral, A. C. K.-B., Piquette, D., Walter, G., Dev, S. P., Taylor, P., Downar, J., & Conn, L. G. (2018) · BMC Health Services Research · doi:10.1186/s12913-018-3341-1 · Cited by 35 · see citing works
Chen, C., Michaels, J., & Meeker, M. A. (2020) · Journal of Palliative Care · doi:10.1177/0825859719874767 · Cited by 34 · see citing works
Reifarth, E., Borrega, J. G., & Kochanek, M. (2022) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2022.103328 · Cited by 38 · see citing works
Orford, N. R., Milnes, S. L., Simpson, N., Keely, G., Elderkin, T., Bone, A., Martin, P., Bellomo, R., Bailey, M., & Corke, C. F. (2017) · BMJ Supportive & Palliative Care · doi:10.1136/bmjspcare-2016-001231 · Cited by 34 · see citing works
Ethik der Reanimation und Entscheidungen am Lebensende
Mentzelopoulos, S. D., Couper, K., de Voorde, P. V., Druwé, P., Blom, M. T., Perkins, G. D., Lulić, I., Djakow, J., Raffay, V. I., Lilja, G., et al. (2021) · Notfall + Rettungsmedizin · doi:10.1007/s10049-021-00888-8 · Cited by 32 · see citing works
Suen, A. O., Butler, R. A., Arnold, R. M., Myers, B. A., Witteman, H. O., Cox, C. E., Argenas, A., Buddadhumaruk, P., Bursic, A. E., Ernecoff, N. C., et al. (2019) · Journal of Critical Care · doi:10.1016/j.jcrc.2019.12.002 · Cited by 33 · see citing works
Family-clinician shared decision making in intensive care units: Cluster randomized trial in China
Liu, X., Humphris, G. M., Luo, A., Yang, M., Jin, Y., Huang, S., Xiao, S., Lv, A., Wu, G., Gui, P., et al. (2021) · Patient Education and Counseling · doi:10.1016/j.pec.2021.10.004 · Cited by 33 · see citing works
Bereavement Support Programs in the Intensive Care Unit: A Systematic Review
Brekelmans, M., Ramnarain, D., & Pouwels, S. (2022) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2022.05.008 · Cited by 36 · see citing works
Neville, T. H., Agarwal, N., Swinton, M. E., Phung, P. G., Xu, X., Kao, Y.-H., Seo, J., Granone, M. C., Hjelmhaug, K., Hainje, J., et al. (2019) · Journal of Palliative Medicine · doi:10.1089/jpm.2019.0135 · Cited by 32 · see citing works
Li, L., Nelson, J. E., Hanson, L. C., Cox, C. E., Carson, S. S., Chai, E. J., Keller, K. L., Tulsky, J. A., & Danis, M. (2018) · Critical Care Medicine · doi:10.1097/ccm.0000000000003035 · Cited by 31 · see citing works
Aligning use of intensive care with patient values in the USA: past, present, and future
Turnbull, A. E., Bosslet, G. T., & Kross, E. K. (2019) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(19)30087-6 · Cited by 31 · see citing works
Dupont, T., Kentish‐Barnes, N., Pochard, F., Duchesnay, É., & Azoulay, É. (2023) · Intensive Care Medicine · doi:10.1007/s00134-023-07288-1 · Cited by 30 · see citing works
Cox, C. E., Ashana, D. C., Riley, I. L., Olsen, M. K., Casarett, D., Haines, K., O’Keefe, Y. A., Al-Hegelan, M. S., Harrison, R. W., Naglee, C., et al. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.49666 · Cited by 30 · see citing works
Complexity Analysis of Decision-Making in the Critically Ill
Daly, B. J., Douglas, S. L., O’Toole, E. E., Rowbottom, J. R., Hoffer, A., Lipson, A. R., & Burant, C. J. (2016) · Journal of Intensive Care Medicine · doi:10.1177/0885066616678394 · Cited by 31 · see citing works
What are the ethical issues in relation to the role of the family in intensive care?
Quenot, J., Ecarnot, F., Meunier‐Beillard, N., Dargent, A., Large, A., Andreu, P., & Rigaud, J. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2017.04.44 · Cited by 30 · see citing works
Kerckhoffs, M. C., Senekal, J., van Dijk, D., Artigas, A., Butler, J., Michalsen, A., van Mol, M. M. C., Moreno, R. P., da Silva, F. P., Picetti, E., et al. (2020) · Critical Care Medicine · doi:10.1097/ccm.0000000000004221 · Cited by 29 · see citing works
Haakma, T., Tieben, R., Sleven, B., Buise, M. P., & van Mol, M. M. C. (2022) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2022.103197 · Cited by 30 · see citing works
Daily Written Care Summaries for Families of Critically Ill Patients: A Randomized Controlled Trial*
Greenberg, J., Basapur, S., Quinn, T. V., Bulger, J. L., Schwartz, N., Oh, S.-K., Ritz, E., Glover, C., & Shah, R. (2022) · Critical Care Medicine · doi:10.1097/ccm.0000000000005583 · Cited by 20 · see citing works
Early Versus Usual Palliative Care Consultation in the Intensive Care Unit
Helgeson, S., Burnside, R., Robinson, M., Mack, R., Ball, C., Guru, P., & Moss, J. (2022) · The American journal of hospice & palliative care · doi:10.1177/10499091221115732 · Cited by 29 · see citing works
Nurse–Family Communication During and After Family Meetings in the Intensive Care Unit
Pecanac, K. E., & King, B. (2019) · Journal of Nursing Scholarship · doi:10.1111/jnu.12459 · Cited by 29 · see citing works
Duberstein, P. R., Maciejewski, P. K., Epstein, R. M., Fenton, J. J., Chapman, B. P., Norton, S. A., Hoerger, M. P., Wittink, M. N., Tancredi, D. J., Xing, G., et al. (2019) · Journal of Palliative Medicine · doi:10.1089/jpm.2019.0078 · Cited by 29 · see citing works
Suen, A. O., Butler, R. A., Arnold, R. M., Myers, B. A., Witteman, H. O., Cox, C. E., McComb, J. G., Buddadhumaruk, P., Shields, A. M., Morse, N., et al. (2020) · Annals of the American Thoracic Society · doi:10.1513/annalsats.202006-585oc · Cited by 29 · see citing works
Palliative and End-of-Life Care: Prioritizing Compassion Within the ICU and Beyond
Aslakson, R. A., Cox, C. E., Baggs, J. G., & Curtis, J. R. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000005208 · Cited by 29 · see citing works
Self-citationHow and when post intensive care syndrome-family is measured: A scoping review
Hayes, K., Harding, S. A., Blackwood, B., & Latour, J. M. (2024) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2024.103768 · Cited by 28 · see citing works
Sviri, S., Geva, D., van Heerden, P. V., Romain, M., Rawhi, H., Abutbul, A., Orenbuch‐Harroch, E., & Bentur, N. (2019) · Journal of Critical Care · doi:10.1016/j.jcrc.2019.01.011 · Cited by 30 · see citing works
Brown, S. M., Bell, S. K., Roche, S. D., Dente, E., Mueller, A., Kim, T.-E., O’Reilly, K. P., Lee, B. S., Sands, K., & Talmor, D. S. (2015) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201509-638oc · Cited by 28 · see citing works
Khandelwal, N., Brumback, L. C., Halpern, S. D., Coe, N. B., Brumback, B., & Curtis, J. R. (2017) · Journal of Palliative Medicine · doi:10.1089/jpm.2016.0548 · Cited by 28 · see citing works
Self-citationPost-Intensive Care Syndrome as a Burden for Patients and Their Caregivers: A Narrative Review
Schembari, G., Santonocito, C., Messina, S., Caruso, A., Cardia, L., Rubulotta, F. M., Noto, A., Bignami, E. G., & Sanfilippo, F. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13195881 · Cited by 31 · see citing works
Palliative Care Needs Assessment in the Neuro-ICU: Effect on Family
Creutzfeldt, C. J., Hanna, M., Cheever, C., Lele, A. V., Spiekerman, C. F., Engelberg, R. A., & Curtis, J. R. (2017) · Neurocritical Care · doi:10.1007/s12028-017-0426-3 · Cited by 27 · see citing works
Self-citationGlobal Comparison of Communication of End-of-Life Decisions in the ICU
Feldman, C. H., Sprung, C. L., Mentzelopoulos, S. D., Pohrt, A., Hartog, C. S., Danbury, C. M., Weiß, M., Avidan, A., Estella, Á., Joynt, G. M., et al. (2022) · CHEST Journal · doi:10.1016/j.chest.2022.05.007 · Cited by 27 · see citing works
Concerns of surrogate decision makers for patients with acute brain injury
Hwang, D. Y., Knies, A. K., Mampre, D. M., Kolenikov, S., Schalk, M., Hammer, H., White, D. B., Holloway, R. G., Sheth, K. N., & Fraenkel, L. (2020) · Neurology · doi:10.1212/wnl.0000000000009406 · Cited by 27 · see citing works
Implementing the SCCM Family-Centered Care Guidelines in Critical Care Nursing Practice
Coombs, M. A., Puntillo, K., Franck, L. S., Scruth, E. A., Harvey, M. A., Swoboda, S. M., & Davidson, J. E. (2017) · AACN Advanced Critical Care · doi:10.4037/aacnacc2017766 · Cited by 26 · see citing works
Matters of Life and Death: Why Do Older Patients Choose Conservative Management?
Saeed, F., Adams, H., & Epstein, R. M. (2019) · American Journal of Nephrology · doi:10.1159/000504692 · Cited by 26 · see citing works
- Authors
- Curtis, J. R., Treece, P. D., Nielsen, E. L., Gold, J., Ciechanowski, P. S., Shannon, S. E., Khandelwal, N., Young, J. P., & Engelberg, R. A.
- Affiliations
- Cambia (AU)
- School of Law
- Department of Psychiatry and Behavioral Sciences, and
- Department of Biobehavioral Nursing and Health Systems, School of Nursing
- University of Washington (US)
- Corresponding author
- Curtis, J. Randall
- ORCID
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-01
- Volume
- 193
- Issue
- 2
- Pages
- 154-162
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- PMC
- PMC4731711
- OpenAlex
- W2128195581
- Cited by
- 398
- References
- 36
- Citations by year
- 2026: 34 · 2025: 29 · 2024: 39 · 2023: 32 · 2022: 49 · 2021: 40 · 2020: 35 · 2019: 40 · 2018: 38 · 2017: 33 · 2016: 23 · 2015: 6
- FWCI
- 66.27
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Respiratory and Critical Care Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Nursing Research (R01 NR05226)
- Topics
- Health Sciences › Health Professions › Radiological and Ultrasound Technology › Family and Patient Care in Intensive Care Units
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Health Professions › General Health Professions › Ethics in medical practice
- Keywords
- family communication, communication facilitators, family distress, end-of-life care, intensive care unit, critically ill patients, surrogate decision makers, family depression, post-traumatic stress disorder, anxiety, ICU costs, length of hospital stay, family conflict mediation
- MeSH terms
- Aged, 80 and over, Communication, Costs and Cost Analysis, Decision Making, Depression, Family, Female, Follow-Up Studies, Humans, Intensive Care Units, Length of Stay, Male, Middle Aged, Palliative Care, Professional-Family Relations, Stress, Psychological, Terminal Care, Negotiating, Withholding Treatment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review