Cited by 176Chronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseasesSmoking Behavior and Cessation

The DOI matches its Crossref record, with a small difference in title or year; 52 of the 52 references it cites were found in a registry or an index; none of the 38 sources its claims cite is checked for support yet.

Health Coaching and Chronic Obstructive Pulmonary Disease Rehospitalization: A Randomized Study

Open access

Abstract

Rationale: Hospital readmission for chronic obstructive pulmonary disease (COPD) has attracted attention owing to the burden to patients and the health care system. There is a knowledge gap on approaches to reducing COPD readmissions. Objectives: To determine the effect of comprehensive health coaching on the rate of COPD readmissions. Methods: A total of 215 patients hospitalized for a COPD exacerbation were randomized at hospital discharge to receive either (1) motivational interviewing–based health coaching plus a written action plan for exacerbations (the use of antibiotics and oral steroids) and brief exercise advice or (2) usual care. Measurements and Main Results: We evaluated the rate of COPD-related hospitalizations during 1 year of follow-up. The absolute risk reductions of COPD-related rehospitalization in the health coaching group were 7.5% (P = 0.01), 11.0% (P = 0.02), 11.6% (P = 0.03), 11.4% (P = 0.05), and 5.4% (P = 0.24) at 1, 3, 6, 9, and 12 months, respectively, compared with the control group. The odds ratios for COPD hospitalization in the intervention arm compared with the control arm were 0.09 (95% confidence interval [CI], 0.01–0.77) at 1 month postdischarge, 0.37 (95% CI, 0.15–0.91) at 3 months postdischarge, 0.43 (95% CI, 0.20–0.94) at 6 months postdischarge, and 0.60 (95% CI, 0.30–1.20) at 1 year postdischarge. The missing value rate for the primary outcome was 0.4% (one patient). Disease-specific quality of life improved significantly in the health coaching group compared with the control group at 6 and 12 months, based on the Chronic Respiratory Disease Questionnaire emotional score (emotion and mastery domains) and physical score (dyspnea and fatigue domains) (P < 0.05). There were no differences between groups in measured physical activity at any time point. Conclusions: Health coaching may represent a feasible and possibly effective intervention designed to reduce COPD readmissions. Clinical trial registered with www.clinicaltrials.gov (NCT01058486).

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

In a randomized trial of 215 patients hospitalized for COPD exacerbation, motivational-interviewing-based health coaching plus a written action plan and brief exercise advice reduced COPD-related rehospitalization at 1, 3, and 6 months but not at 12 months. Disease-specific quality of life improved at 6 and 12 months, while measured physical activity did not differ between groups.

Key findings

  • COPD-related rehospitalization absolute risk reductions were 7.5% at 1 month (P = 0.01), 11.0% at 3 months (P = 0.02), 11.6% at 6 months (P = 0.03), 11.4% at 9 months (P = 0.05), and 5.4% at 12 months (P = 0.24); the corresponding odds ratios were 0.09 (95% CI, 0.01–0.77) at 1 month, 0.37 (95% CI, 0.15–0.91) at 3 months, 0.43 (95% CI, 0.20–0.94) at 6 months, and 0.60 (95% CI, 0.30–1.20) at 12 months.
  • Number needed to treat to prevent one hospitalization was 13 at 1 month, 9 at 3 months, and 8 at 6 months; for every 10 patients treated, there were 3 fewer hospital days at 1 month, 4 fewer at 3 months, and 8 fewer at 6 months.
  • Disease-specific quality of life improved significantly in the health coaching group at 6 and 12 months on the Chronic Respiratory Disease Questionnaire emotional and physical scores (P < 0.05), with NNT of 6–7 for clinically meaningful improvement at 6 months.
  • There were no differences between groups in measured physical activity at any time point; confirmed exacerbations were greater in the control group than the intervention group over 12 months (mean [SD], 1.15 [1.5] vs. 0.8 [1.5]; P = 0.03).

Methods

  • Multisite randomized trial conducted September 2010 to August 2014 at Mayo Clinic and HealthPartners Regions Hospital; 215 patients admitted for a COPD exacerbation, older than 40 years, with more than 10 pack-years smoking, English-speaking, and telephone access were randomized at hospital discharge, stratified by center.
  • Intervention was motivational-interviewing-based health coaching plus a written action plan for exacerbations (prednisone 40 mg orally and a generic antibiotic for 5 days) and brief exercise advice; control received guideline-based usual care, with both groups referred for conventional pulmonary rehabilitation.
  • Primary outcome was rate of COPD-related rehospitalization over 1 year; secondary outcomes included disease-specific quality of life (CRQ) and measured physical activity at 6 and 12 months. Analyses used chi-square tests and logistic models adjusted for age, FEV1, mMRC score, and prior hospitalizations, with bootstrap sensitivity analyses.

Limitations

  • The paper states the study was powered to detect a difference in hospitalization at 12 months, which was not found; the authors believe intermediate time-point differences are robust but cannot know the exact contributory effect of each intervention component.
  • The paper notes the intervention did not increase measured physical activity, and possible reasons for the lack of 12-month effect include decreasing secular readmission rates and reduced intervention intensity after Month 3.
  • Evident from the text: participants and coaches were not blinded, although outcome assessors and adjudicating pulmonologists were blinded; the intervention was multicomponent, and the two-site U.S. sample may limit generalizability.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1164/rccm.201512-2503oc

Cites

52 of 52 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

25 Not checked yet · 20 Own result · 15 Own method · 10 Own interpretation · 3 No basis given

Verify all 38 references — free account

Show all 38 claims

  • It may state two separate claims as one. 22
  • Probably not a substantial claim. 15
35 of 35
  • The paper relies on this without support.

    Health coaching is low cost.

    “We found health coaching to be a simple and trainable intervention with low cost and that was feasible (not requiring transportation, unlike PR) and had a high likelihood of replication, given the expansive availability of health coaching training programs.”
  • The paper relies on this without support.

    Greater pulmonary rehabilitation attendance in the intervention group did not account for the reduction in COPD hospitalizations.

    “Attendance at PR visits in the fi rst 3 months after discharge (as part of the patient ' s discharge plan, not research) was greater in the intervention group than in the control group (50% vs. 33%; P = 0.017).”
2 of 2

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Citations

Cites

Show all 52 references

Research works printed but not linked: 1

  1. Lorig, 2006, Living a healthy life with chronic conditions: self-management of heart disease, arthritis, diabetes, asthma, bronchitis, emphysema and others.

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Metadata

Authors
Benzo, R., Vickers, K., Novotny, P. J., Tucker, S., Hoult, J., Neuenfeldt, P., Connett, J., Lorig, K., & McEvoy, C.
Affiliations
  • Mindful Breathing Laboratory, Division of Pulmonary and Critical Care Medicine
  • Department of Psychology, and
  • Mayo Clinic (US)
  • University of Iowa (US)
  • HealthPartners (US)
  • University of Minnesota (US)
  • Stanford University (US)
Corresponding author
Benzo, Roberto
Venue
American Journal of Respiratory and Critical Care Medicine
Published
2016-09
Volume
194
Issue
6
Pages
672-680
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
OpenAlex
W2519121194
Cited by
176
References
52
Citations by year
2026: 8 · 2025: 4 · 2024: 16 · 2023: 18 · 2022: 22 · 2021: 23 · 2020: 24 · 2019: 19 · 2018: 11 · 2017: 27 · 2016: 4
FWCI
18.19
Type
journal article
Language
en
Open access
Locations
  • American Journal of Respiratory and Critical Care Medicine (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
NHLBI (R01 HL09468)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Keywords
health coaching, chronic obstructive pulmonary disease, hospital readmission, COPD exacerbations, motivational interviewing, action plan, exercise recommendations, disease-specific quality of life, post-discharge care, physical activity, antibiotic use, oral corticosteroids, Chronic Respiratory Questionnaire, dyspnea, fatigue, emotional mastery, patient education, health behavior change
MeSH terms
Mentoring, Aged, Exercise Therapy, Female, Humans, Male, Patient Readmission, Quality of Life, Pulmonary Disease, Chronic Obstructive, Motivational Interviewing

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