Down-Regulated NF-E2–Related Factor 2 in Pulmonary Macrophages of Aged Smokers and Patients with Chronic Obstructive Pulmonary Disease
Suzuki, Masaru, Betsuyaku, Tomoko, Ito, Yoko, Nagai, Katsura, Nasuhara, Yasuyuki, Kaga, Kichizo, Kondo, Satoshi, Nishimura, Masaharu·2008·American Journal of Respiratory Cell and Molecular Biology
Cited by (286)
Items 101–200 of 286
- Serum Oxidative Stress-Induced Repression of Nrf2 and GSH Depletion: A Mechanism Potentially Involved in Endothelial Dysfunction of Young SmokersAnna Fratta Pasini, Anna Albiero, Chiara Stranieri, Mattia Cominacini, Andrea Pasini, Chiara Mozzini, Paola Vallerio, Luciano Cominacini, Ulisse Garbin · 2012 · PLoS ONE
- Oxidative stress in retinal pigment epithelium degeneration: from pathogenesis to therapeutic targets in dry age-related macular degenerationMaurya, Meenakshi, Bora, Kiran, Blomfield, Alexandra K., Pavlovich, Madeline C., Huang, Shuo, Liu, Chi-Hsiu, Chen, Jing · 2023 · Neural Regeneration Research
- Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)–like 2Anne M. Fitzpatrick, Susan T. Stephenson, Graham R. Hadley, Leandrea Burwell, Madhuri Penugonda, Dawn M. Simon, Jason M. Hansen, Dean P. Jones, Lou Ann S. Brown · 2011 · Journal of Allergy and Clinical Immunology
- Oxidative stress as a therapeutic target for the prevention and treatment of early age-related macular degenerationSayena Jabbehdari, James T. Handa · 2020 · Survey of Ophthalmology
- 14,15-Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagyYunxiao Li, Ganggang Yu, Shaopeng Yuan, Chunting Tan, Jianlin Xie, Yasi Ding, Puqiao Lian, Lixia Fu, Qi Hou, Bo Xu et al. · 2016 · American Journal of Physiology-Lung Cellular and Molecular Physiology
- Bromodomain and Extraterminal Proteins Suppress NF-E2–Related Factor 2–Mediated Antioxidant Gene ExpressionCharalambos Michaeloudes, Nicolas Mercado, Colin Clarke, Pankaj Kumar Bhavsar, Ian Michael Adcock, Peter John Barnes, Kian Fan Chung · 2014 · The Journal of Immunology
- Vitamin E prevents NRF2 suppression by allergens in asthmatic alveolar macrophages in vivoRyszard Dworski, Wei Han, Timothy S. Blackwell, Aimee Hoskins, Michael L. Freeman · 2011 · Free Radical Biology and Medicine
- Role of Transcription Factors in the Pathogenesis of Asthma and COPDGaetano Caramori, Paolo Casolari, Ian Michael Adcock · 2013 · Cell Communication & Adhesion
- Therapeutic Potential of Small Molecules Targeting Oxidative Stress in the Treatment of Chronic Obstructive Pulmonary Disease (COPD): A Comprehensive ReviewHamad Ghaleb Dailah · 2022 · Molecules
- Smoking as a contributing factor for development of polycythemia vera and related neoplasmsHans Carl Hasselbalch · 2015 · Leukemia Research
- Update on the pathological processes, molecular biology, and clinical utility of N-acetylcysteine in chronic obstructive pulmonary diseaseHoi Nam Tse, Cee Zhung Steven Tseng · 2014 · International Journal of COPD
- Nrf2 is required for normal postnatal bone acquisition in miceJung‐Hyun Kim, Vandana Singhal, Shyam S. Biswal, Rajesh Kumar Thimmulappa, Douglas J. DiGirolamo · 2014 · Bone Research
- Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general populationMateusz Siedliński, Dirkje Sjoukje Postma, Jolanda M.A. Boer, Gerrit van der Steege, Jan P. Schouten, Henriëtte A. Smit, H. Marike Boezen · 2009 · Respiratory Research
- Association of Nrf2 with airway pathogenesis: lessons learned from genetic mouse modelsHye‐Youn Cho, Steven R. Kleeberger · 2015 · Archives of Toxicology
- The Unfolded Protein Response in Chronic Obstructive Pulmonary Disease.Steven G. Kelsen · 2016 · Europe PMC (PubMed Central)
- Emerging pharmaceutical therapies for COPDSowmya P. Lakshmi, Aravind Reddy, Raju C. Reddy · 2017 · International Journal of COPD
- Vitamin E isoform γ-tocotrienol protects against emphysema in cigarette smoke-induced COPDHong Yong Peh, W.S. Daniel Tan, Tze Khee Chan, Chen Wei Pow, Paul S. Foster, W.S. Fred Wong · 2017 · Free Radical Biology and Medicine
- Baicalin alleviates hyperglycemia-induced endothelial impairment via Nrf2Gen Chen, Xiangjuan Chen, Chao Niu, Xiaozhong Huang, Ning An, Jia Man Sun, Shuai Huang, Weijian Ye, Santie Li, Yingjie Shen et al. · 2018 · Journal of Endocrinology
- Sulforaphane increases Nrf2 expression and protects alveolar epithelial cells against injury caused by cigarette smoke extractZongxian Jiao, Jiachen Chang, Jing Li, Dengmei Nie, Huijuan Cui, Dongfang Guo · 2017 · Molecular Medicine Reports
- Experimental Therapeutics of Nrf2 as a Target for Prevention of Bacterial Exacerbations in COPDShyam S. Biswal, Rajesh Kumar Thimmulappa, Christopher J. Harvey · 2012 · Proceedings of the American Thoracic Society
- Lung injury after cigarette smoking is particle relatedAndrew J. Ghio, Sangani Rahul · 2011 · International Journal of COPD
- Zinc Prevents the Development of Diabetic Cardiomyopathy in db/db MiceShudong Wang, Bowei Wang, Yuehui Wang, Qian Tong, Quan Liu, Jian Sun, Yang Zheng, Lu Cai · 2017 · International Journal of Molecular Sciences
- Dual anti-oxidant and anti-inflammatory actions of the electrophilic cyclooxygenase-2-derived 17-oxo-DHA in lipopolysaccharide- and cigarette smoke-induced inflammationChiara Cipollina, Serena Di Vincenzo, Stefania Gerbino, Liboria Siena, Mark Gjomarkaj, Elisabetta Pace · 2014 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Senescence: Pathogenic Driver in Chronic Obstructive Pulmonary DiseaseMelissa Rivas, Gayatri Gupta, Louis Costanzo, Huma Ahmed, Anne E. Wyman, Patrick M. Geraghty · 2022 · Medicina
- Increased endoplasmic reticulum stress and Nrf2 repression in peripheral blood mononuclear cells of patients with stable coronary artery diseaseChiara Mozzini, Anna Fratta Pasini, Ulisse Garbin, Chiara Stranieri, Andrea Pasini, Paola Vallerio, Luciano Cominacini · 2014 · Free Radical Biology and Medicine
- Reactivity of mouse alveolar macrophages to cigarette smoke is strain dependentDaniela Vecchio, Beatrice Arezzini, Alessandra Pecorelli, Giuseppe Valacchi, Piero A. Martorana, Concetta Gardi · 2010 · American Journal of Physiology-Lung Cellular and Molecular Physiology
- Ursolic acid attenuates cigarette smoke-induced emphysema in rats by regulating PERK and Nrf2 pathwaysLi Lin, Yan Yin, Gang Hou, Dan Han, Jian Kang, Qiuyue Wang · 2017 · Pulmonary Pharmacology & Therapeutics
- Corynoline attenuates LPS-induced acute lung injury in mice by activating Nrf2Yan Liu, Man Shu Song, Guangfa Zhu, Xi Xin, Keng Li, Chunting Wu, Lixue Huang · 2017 · International Immunopharmacology
- Uncovering the Role of Oxidative Imbalance in the Development and Progression of Bronchial AsthmaLuiz Henrique César Vasconcelos, Sarah Rebeca Dantas Ferreira, Maria da Conceição Correia Silva, Paula Benvindo Ferreira, Iara Leão Luna de Souza, Fabiana de Andrade Cavalcante, Bagnólia Araújo da Silva · 2021 · Oxidative Medicine and Cellular Longevity
- COPD lung studies of Nrf2 expression and the effects of Nrf2 activatorsJian Li, James M. Baker, Andrew Higham, Rajesh D. Shah, Ángeles Montero, Clare M. Murray, Nicky Cooper, Cathy Lucas, Craig Fox, Dave Singh et al. · 2022 · Inflammopharmacology
- Endoplasmic Reticulum Stress, NRF2 Signalling and Cardiovascular Diseases in a NutshellChiara Mozzini, Luciano Cominacini, Ulisse Garbin, Anna Maria Fratta Pasini · 2017 · Current Atherosclerosis Reports
- The aging lung: microenvironment, mechanisms, and diseasesYanmei Wang, Xuewen Huang, Guofeng Luo, Yunying Xu, Xiqian Deng, Yumeng Lin, Zhanzhan Wang, Shuwei Zhou, Siyu Wang, Haoran Chen et al. · 2024 · Frontiers in Immunology
- Nrf2 expression is increased in peripheral blood mononuclear cells derived from mild–moderate ex-smoker COPD patients with persistent oxidative stressAnna Maria Fratta Pasini, Marcello Ferrari, Chiara Stranieri, Paola Vallerio, Chiara Mozzini, Ulisse Garbin, Giorgia Zambon, Luciano Cominacini · 2016 · International Journal of COPD
- The ageing lung under stressMartina Korfei, BreAnne MacKenzie, Silke Meiners · 2020 · European Respiratory Review
- Antioxidants in smokersEmanuela Astori, Maria Lisa Garavaglia, Graziano Colombo, Lucia Landoni, Nicola Marcello Portinaro, Aldo Milzani, Isabella Dalle‐Donne · 2021 · Nutrition Research Reviews
- An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort studyHironori Masuko, Tohru Sakamoto, Yoshiko Kaneko, Hiroaki Iijima, Takashi Naito, Emiko Noguchi, Tomomitsu Hirota, Mayumi Tamari, Nobuyuki Hizawa · 2011 · BMC Medical Genetics
- Susceptibility of the Aging Lung to Environmental InjuryLei Wang, Francis Green, Suzette M. Smiley‐Jewell, Kent E. Pinkerton · 2010 · Seminars in Respiratory and Critical Care Medicine
- A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for interventionRuben D. Prange, Marcus Thiedmann, Anita Bhandari, Neha Mishra, Anupam N. Sinha, Robert Häsler, Philip C Rosenstiel, Karin Uliczka, Christina Wagner, Ali Önder Yildirim et al. · 2018 · Aging
- Targeting defective pulmonary innate immunity – A new therapeutic option?Kylie B. R. Belchamber, Louise Donnelly · 2020 · Pharmacology & Therapeutics
- Regulation of Cigarette Smoke (CS)-Induced Autophagy by Nrf2Lingxiang Zhu, Erika C. Barret, Yuxue Xu, Zuguo Liu, Aditya Manoharan, Yin Chen · 2013 · PLoS ONE · Retracted
- Nrf2 Regulates Chronic Lung Inflammation and B-Cell Responses to Nontypeable Haemophilus influenzaeAmit Anand Lugade, R. Robert Vethanayagam, Mehrab Nasirikenari, Paul N. Bogner, Brahm H. Segal, Yasmin M. Thanavala · 2011 · American Journal of Respiratory Cell and Molecular Biology
- NFE2L2 polymorphisms, mortality, and metabolism in the general populationSylwia Marta Figarska, Judith M. Vonk, H. Marike Boezen · 2014 · Physiological Genomics
- Nrf2 Is a Protective Factor against Oxidative Stresses Induced by Diesel Exhaust Particle in Allergic AsthmaYingji Li, Tomoyuki Kawada, Arata Azuma · 2013 · Oxidative Medicine and Cellular Longevity
- Endoplasmic reticulum stress and Nrf2 repression in circulating cells of type 2 diabetic patients without the recommended glycemic goalsChiara Mozzini, Ulisse Garbin, Chiara Stranieri, A. Pasini, Erika Solani, Irene Alessandra Tinelli, Luciano Cominacini, Anna Maria Fratta Pasini · 2014 · Free Radical Research
- NRF2 in age-related musculoskeletal diseases: Role and treatment prospectsXiangyu Zhang, Hengzhen Li, Lin Chen, Yuxiang Wu, Yusheng Li · 2023 · Genes & Diseases
- Functional haplotypes in the promoter region of transcription factor Nrf2 in chronic obstructive pulmonary disease.Chung‐Ching Hua, Liang‐Che Chang, Jo‐Chi Tseng, Chien‐Ming Chu, Yu‐Chih Liu, Wen-Bin Shieh · 2010 · Europe PMC (PubMed Central)
- Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary diseaseKen‐ichiro Tanaka, Tomoaki Ishihara, Toshifumi Sugizaki, Daisuke Kobayashi, Yasunobu Yamashita, Kayoko Tahara, Naoki Yamakawa, Kumiko Iijima, Kaoru Mogushi, Hiroshi Tanaka et al. · 2013 · Nature Communications
- Sulforaphane inhibitsde novosynthesis of IL-8 and MCP-1 in human epithelial cells generated by cigarette smoke extractWarren Starrett, David J. Blake · 2011 · Journal of Immunotoxicology
- Iron-Regulated Reactive Oxygen Species Production and Programmed Cell Death in Chronic Obstructive Pulmonary DiseaseKenji Mizumura, Yasuhiro Gon · 2021 · Antioxidants
- Innate Immune Modulation in Chronic Obstructive Pulmonary Disease: Moving Closer toward Vitamin D TherapyNele Heulens, Hannelie Korf, Wim Janssens · 2015 · Journal of Pharmacology and Experimental Therapeutics
- Aging Enhances Susceptibility to Cigarette Smoke–Induced Inflammation through Bronchiolar ChemokinesChinatsu Moriyama, Tomoko Betsuyaku, Yoko Ito, Ichiro Hamamura, Junko Hata, Hiroshi Takahashi, Yasuyuki Nasuhara, Masaharu Nishimura · 2009 · American Journal of Respiratory Cell and Molecular Biology
- Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264.7 Cells through Activation of the Nrf2-ARE PathwayShih‐Yu Lee, Po-Yu Chen, Jung‐Chun Lin, Nicholas S. Kirkby, Ching‐Huei Ou, Tsu‐Chung Chang · 2017 · The American Journal of Chinese Medicine
- The mechanistic insights of the antioxidant Keap1-Nrf2 pathway in oncogenesis: a deadly scenarioAnirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan · 2023 · Medical Oncology
- Acrolein exposure suppresses antigen-induced pulmonary inflammationPage C. Spiess, David I. Kasahara, Aida Habibovic, Milena Hristova, Matthew J. Randall, Matthew E. Poynter, Albert van der Vliet · 2013 · Respiratory Research
- Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary diseaseIrfan Rahman, Vuokko L. Kinnula · 2012 · Expert Review of Clinical Pharmacology
- Cellular senescence—an aging hallmark in chronic obstructive pulmonary disease pathogenesisJun Araya, Kazuyoshi Kuwano · 2021 · Respiratory Investigation
- Chaperone-Mediated Autophagy Suppresses Apoptosis via Regulation of the Unfolded Protein Response during Chronic Obstructive Pulmonary Disease PathogenesisYusuke Hosaka, Jun Araya, Yu Fujita, Tsukasa Kadota, Kazuya Tsubouchi, Masahiro Yoshida, Shunsuke Minagawa, Hiromichi Hara, Hironori Kawamoto, Naoaki Watanabe et al. · 2020 · The Journal of Immunology
- Indoxyl Sulfate and p-Cresyl Sulfate in Chronic Kidney Disease. Could These Toxins Modulate the Antioxidant Nrf2-Keap1 Pathway?Milena Barcza Stockler‐Pinto, Denis P. Fouque, Christophe Olivier Soulage, Marine L. Croze, Denise Mafra · 2014 · Journal of Renal Nutrition
- Bronchiolar epithelial catalase is diminished in smokers with mild COPDTomoko Betsuyaku, Satoshi Fuke, Takashi Inomata, Kichizo Kaga, Toshiaki Morikawa, Nao Odajima, Tracy L. Adair-Kirk, Masaharu Nishimura · 2012 · European Respiratory Journal
- Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseasesCuadrado, Antonio, Cazalla, Eduardo, Bach, Anders, Bathish, Boushra, Naidu, Sharadha Dayalan, DeNicola, Gina M., Dinkova-Kostova, Albena T., Fernández-Ginés, Raquel, Grochot-Przeczek, Anna, Hayes, John D. et al. · 2025 · Redox Biology
- Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPDVenkataramana K. Sidhaye, Janet T. Holbrook, Alyce E. Burke, Kuladeep R. Sudini, Sanjay Sethi, Gerard J. Criner, Jed W. Fahey, Charles S. Berenson, Michael R. Jacobs, Rajesh Kumar Thimmulappa et al. · 2019 · Respiratory Research
- Trans-4,4′-dihydroxystilbene ameliorates cigarette smoke-induced progression of chronic obstructive pulmonary disease via inhibiting oxidative stress and inflammatory responseTian Wang, Fang Dai, Guo-Hui Li, Xuemei Chen, Yanru Li, Shuqi Wang, Dong‐Mei Ren, Xiao‐Ning Wang, Hong‐Xiang Lou, Bo Zhou et al. · 2019 · Free Radical Biology and Medicine
- Red Blood Cells Protect Albumin from Cigarette Smoke–Induced OxidationGraziano Colombo, Ranieri Rossi, Nicoletta Gagliano, Nicola Marcello Portinaro, Marco Clerici, Andrea Annibal, Daniela Giustarini, Roberto Colombo, Aldo Milzani, Isabella Dalle‐Donne · 2012 · PLoS ONE
- Markers of anti-oxidant response in tobacco smoke exposed subjects: A data-mining reviewAlessia Comandini, Valeria Marzano, Giacomo Curradi, Giorgio Federici, Andrea Urbani, Cesare Saltini · 2010 · Pulmonary Pharmacology & Therapeutics
- Functional Haplotypes in the Promoter Region of Transcription FactorNrf2in Chronic Obstructive Pulmonary DiseaseChung‐Ching Hua, Liang‐Che Chang, Jo‐Chi Tseng, Chien‐Ming Chu, Yu‐Chih Liu, Wen-Bin Shieh · 2010 · Disease Markers
- The anti‐inflammatory effects of PGE2on human lung macrophages are mediated by the EP4receptorSharonjit K Gill, Yiwen Yao, Linda J. Kay, Martin A. Bewley, Helen M. Marriott, Peter T. Peachell · 2016 · British Journal of Pharmacology
- Aging affects lipopolysaccharide-induced upregulation of heme oxygenase-1 in the lungs and alveolar macrophagesYoko Ito, Tomoko Betsuyaku, Chinatsu Moriyama, Yasuyuki Nasuhara, Masaharu Nishimura · 2008 · Biogerontology
- Ilex paraguariensis extracts and its polyphenols prevent oxidative damage and senescence of human retinal pigment epithelium cellsPablo S. Tate, Mariela Claudia Marazita, Melisa D. Marquioni‐Ramella, Ángela M. Suburo · 2020 · Journal of Functional Foods
- Redox Regulation in Aging Lungs and Therapeutic Implications of Antioxidants in COPDHirofumi Kiyokawa, Yuma Hoshino, Kazuhiro Sakaguchi, Shigeo Muro, Junji Yodoi · 2021 · Antioxidants
- Heat-Not-Burn cigarette induces oxidative stress response in primary rat alveolar epithelial cellsYoko Ito, Kana Oshinden, Naokata Kutsuzawa, Chinatsu Kohno, Sanae Isaki, Keiko Yokoyama, Tadayuki Sato, Masayuki Tanaka, Koichiro Asano · 2020 · PLoS ONE
- Dietary zinc modifies diabetic-induced renal pathology in ratsWael M. Elsaed, Hazem Abdelhamid Mohamed · 2016 · Renal Failure
- Fenretinide Causes Emphysema, Which Is Prevented by Sphingosine 1-PhoshateMasanori Yasuo, Shiro Mizuno, Jeremy C. Allegood, Donatas Kraskauskas, Harm Jan Bogaard, Sarah Spiegel, Norbert Felix Voelkel · 2013 · PLoS ONE
- Carbocisteine Reduces Virus-Induced Pulmonary Inflammation in Mice Exposed to Cigarette SmokeYuichi Yageta, Yukio Ishii, Yuko Morishima, Satoshi Ano, Shigeo Ohtsuka, Masashi Matsuyama, Kaoru Takeuchi, Ken Itoh, Masayuki P. Yamamoto, Nobuyuki Hizawa · 2013 · American Journal of Respiratory Cell and Molecular Biology
- Guideline for the management of upper respiratory tract infections.Adrian John Brink, Mark Frederic Cotton, Charles H. Feldman, Leon Geffen, Willy Hendson, Maurice Hockman, Gary Maartens, Shabir Ahmed Madhi, M Mutua-Mpungu, George H. Swingler · 2004 · PubMed
- Role of Nrf2 and exercise in alleviating COPD-induced skeletal muscle dysfunctionMeiling Jiang, Peijun Li, Yingqi Wang, Yuanyuan Cao, Xiaoyu Han, Linhong Jiang, Xiaodan Liu, Weibing Wu · 2023 · Therapeutic Advances in Respiratory Disease
- Cigarette smoke induces pulmonary arterial dysfunction through an imbalance in the redox status of the soluble guanylyl cyclaseJavier Sevilla‐Montero, Onofre Munar-Rubert, J. Pino-Fadón, Carlota Aguilar-Latorre, Marta Villegas-Esguevillas, B. Climent, Mauro Agrò, Carmen Choya-Foces, Antonio Martı́nez-Ruiz, Eduardo Balsa et al. · 2022 · Free Radical Biology and Medicine
- Immunological Basis of Oxidative Stress-Induced Lung Inflammation in Asthma and COPDGurupreet Singh Sethi, Vivek Dharwal, Amarjit Singh Naura · 2019 · Springer eBooks
- Antrolone, a Novel Benzoid Derived from Antrodia cinnamomea, Inhibits the LPS-Induced Inflammatory Response in RAW264.7 Macrophage Cells by Balancing the NF-κB and Nrf2 PathwaysI‐Chuan Yen, Li-Shian Shi, Min-Chieh Chung, Blerina Ahmetaj‐Shala, Tsu‐Chung Chang, Shih‐Yu Lee · 2018 · The American Journal of Chinese Medicine
- Large‐scale plasma proteomics can reveal distinct endotypes in chronic obstructive pulmonary disease and severe asthmaMasaru Suzuki, John Cole, Satoshi Konno, Hironi Makita, Hiroki Kimura, Masaharu Nishimura, Rose A. Maciewicz · 2021 · Clinical and Translational Allergy
- Chemical and Physical Approaches to Extend the Replicative and Differentiation Potential of Stem CellsEun Seong Hwang, J. Ok, SeonBeom Song · 2016 · Stem Cell Reviews and Reports
- Telomere Length Measurement in Different Ocular Structures: A Potential Implication in Corneal Endothelium PathogenesisMarie‐Catherine Drigeard Desgarnier, Corinne Zinflou, Justin D. Mallet, Sébastien P. Gendron, Sébastien J. Méthot, Patrick J. Rochette · 2016 · Investigative Ophthalmology & Visual Science
- BET‐ting on Nrf2: How Nrf2 Signaling can Influence the Therapeutic Activities of BET Protein InhibitorsNirmalya Chatterjee, Dirk Bohmann · 2018 · BioEssays
- Oxidative Stress and Antioxidants in Pediatric Asthma’s Evolution and ManagementIleana Katerina Ioniuc, Ancuta Lupu, Felicia Dragan, Irina Tarnita, Monica Mihaela Alexoae, Violeta Ștreangă, Costică Mitrofan, Aye Aung Thet, Alin Horațiu Nedelcu, Delia Lidia Șalaru et al. · 2024 · Antioxidants
- 4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary DiseaseWenjing Yang, Xuemei Chen, Shuqi Wang, Hui‐Xin Hu, Xin-Ping Cheng, Lin‐Tao Xu, Dong‐Mei Ren, Xiao‐Ning Wang, Baobing Zhao, Hong‐Xiang Lou et al. · 2020 · Journal of Natural Products
- Redox-dependent induction of antioxidant defenses by phenolic diterpenes confers stress tolerance in normal human skin fibroblasts: Insights on replicative senescenceAna Cristina Carvalho, Andreia Castro Gomes, Cristina Pereira‐Wilson, Cristóvão F. Lima · 2015 · Free Radical Biology and Medicine
- Relationship between neutrophil influx and oxidative stress in alveolar space in lipopolysaccharide-induced lung injuryTakayuki Yoshida, Keita Nagai, Takashi Inomata, Yoko Ito, Tomoko Betsuyaku, Masaharu Nishimura · 2013 · Respiratory Physiology & Neurobiology
- Regulation of NRF2, AP‐1 and NF‐κB by cigarette smoke exposure in three‐dimensional human bronchial epithelial cellsTakashi Sekine, Tadashi Hirata, Shinkichi Ishikawa, Shigeaki Ito, Kanae Ishimori, Kazushi Matsumura, Katsuhiko Muraki · 2018 · Journal of Applied Toxicology
- Retinal Microenvironment Imbalance in Dry Age-Related Macular Degeneration: A Mini-ReviewBrad P. Barnett, James T. Handa · 2013 · Gerontology
- Mir-29b mediates the regulation of Nrf2 on airway epithelial remodeling and Th1/Th2 differentiation in COPD ratsYumin Chi, Qingguo Di, Guangchao Han, Min Li, Baohua Sun · 2019 · Saudi Journal of Biological Sciences
- Disruption of Sinonasal Epithelial Nrf2 Enhances Susceptibility to Rhinosinusitis in a Mouse ModelMurugappan Ramanathan, Anuj Tharakan, Venkataramana K. Sidhaye, Andrew P. Lane, Shyam S. Biswal, Nyall R. London · 2020 · The Laryngoscope
- Cigarette smoke induces alterations in the drug-binding properties of human serum albuminMarco Clerici, Graziano Colombo, Francesco Secundo, Nicoletta Gagliano, Roberto Colombo, Nicola Marcello Portinaro, Daniela Giustarini, Aldo Milzani, Ranieri Rossi, Isabella Dalle‐Donne · 2014 · Blood Cells Molecules and Diseases
- Non-coding RNAs as Regulators of Cellular Senescence in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary DiseaseNorihito Omote, Maor Sauler · 2020 · Frontiers in Medicine
- Serum heme oxygenase-1 measurement is useful for evaluating disease activity and outcomes in patients with acute respiratory distress syndrome and acute exacerbation of interstitial lung diseaseRyo Nagasawa, Yu Hara, Kota Murohashi, Ayako Aoki, Nobuaki Kobayashi, Shigeto Takagi, Satoru Hashimoto, Akihiko Kawana, Takeshi Kaneko · 2020 · BMC Pulmonary Medicine
- Nrf-2 as a novel target in radiation induced lung injuryYuanyuan Chen, Meng Wang, Chenyang Zuo, Meng-Xia Mao, Xiaochun Peng, Jun Cai · 2024 · Heliyon
- A Brief Review of Chronic Obstructive Pulmonary DiseaseJames C. Hogg · 2012 · Canadian Respiratory Journal
- Bone marrow-derived mesenchymal stem cells ameliorate liver injury in a rat model of sepsis by activating Nrf2 signalingSally A. Selim, Samia Adel Abd El-Baset, Asmaa A. A. Kattaia, Eman M. Askar, Eman Abd Elkader · 2018 · Histochemistry and Cell Biology
- Nrf2 and the Nrf2-Interacting Network in Respiratory Inflammation and DiseasesJennifer Carlson, Lindsey Price, Huai Deng · 2020 · Progress in inflammation research
- DJ-1 modulates Nrf2-mediated MRP1 expression by activating Wnt3a/β-catenin signalling in A549 cells exposed to cigarette smoke extract and LPSJian Zhou, Chuanzong Qi, Xin Hua Fang, Zi‐Hao Wang, Shuyi Zhang, Dalang Li, Jue Song · 2021 · Life Sciences
- Charge-switchable, anti-oxidative molecule tuned polyelectrolyte multilayered films: Amplified polyelectrolyte diffusivity and accelerated diabetes wound healingGang Zheng, Di Zhang, Qian Tang, Haiwei Ma, Xiaoyu Dong, Yanlin Chen, Wen-Fei Ni, Bailiang Wang, Huazi Xu, Liyan Shen · 2021 · Chemical Engineering Journal
- Dysregulated Nrf2 signaling in response to di(2-ethylhexyl) phthalate in neutrophils of children with autismAhmed Nadeem, Sheikh F. Ahmad, Naif Obaid Al-Harbi, Laila Yousef AL-Ayadhi, Mohammed Mufadhe Alanazi, Ali S. Alfardan, Sabry Mohamed Attia, Mohammad Algahtani, Saleh A. Bakheet · 2022 · International Immunopharmacology