Down-Regulated NF-E2–Related Factor 2 in Pulmonary Macrophages of Aged Smokers and Patients with Chronic Obstructive Pulmonary Disease

Suzuki, Masaru, Betsuyaku, Tomoko, Ito, Yoko, Nagai, Katsura, Nasuhara, Yasuyuki, Kaga, Kichizo, Kondo, Satoshi, Nishimura, Masaharu·2008·American Journal of Respiratory Cell and Molecular Biology

Cited by (286)

Items 101–200 of 286

  1. Serum Oxidative Stress-Induced Repression of Nrf2 and GSH Depletion: A Mechanism Potentially Involved in Endothelial Dysfunction of Young Smokers
    Anna Fratta Pasini, Anna Albiero, Chiara Stranieri, Mattia Cominacini, Andrea Pasini, Chiara Mozzini, Paola Vallerio, Luciano Cominacini, Ulisse Garbin · 2012 · PLoS ONE
  2. Oxidative stress in retinal pigment epithelium degeneration: from pathogenesis to therapeutic targets in dry age-related macular degeneration
    Maurya, Meenakshi, Bora, Kiran, Blomfield, Alexandra K., Pavlovich, Madeline C., Huang, Shuo, Liu, Chi-Hsiu, Chen, Jing · 2023 · Neural Regeneration Research
  3. Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)–like 2
    Anne M. Fitzpatrick, Susan T. Stephenson, Graham R. Hadley, Leandrea Burwell, Madhuri Penugonda, Dawn M. Simon, Jason M. Hansen, Dean P. Jones, Lou Ann S. Brown · 2011 · Journal of Allergy and Clinical Immunology
  4. Oxidative stress as a therapeutic target for the prevention and treatment of early age-related macular degeneration
    Sayena Jabbehdari, James T. Handa · 2020 · Survey of Ophthalmology
  5. 14,15-Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy
    Yunxiao Li, Ganggang Yu, Shaopeng Yuan, Chunting Tan, Jianlin Xie, Yasi Ding, Puqiao Lian, Lixia Fu, Qi Hou, Bo Xu et al. · 2016 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  6. Bromodomain and Extraterminal Proteins Suppress NF-E2–Related Factor 2–Mediated Antioxidant Gene Expression
    Charalambos Michaeloudes, Nicolas Mercado, Colin Clarke, Pankaj Kumar Bhavsar, Ian Michael Adcock, Peter John Barnes, Kian Fan Chung · 2014 · The Journal of Immunology
  7. Vitamin E prevents NRF2 suppression by allergens in asthmatic alveolar macrophages in vivo
    Ryszard Dworski, Wei Han, Timothy S. Blackwell, Aimee Hoskins, Michael L. Freeman · 2011 · Free Radical Biology and Medicine
  8. Role of Transcription Factors in the Pathogenesis of Asthma and COPD
    Gaetano Caramori, Paolo Casolari, Ian Michael Adcock · 2013 · Cell Communication & Adhesion
  9. Therapeutic Potential of Small Molecules Targeting Oxidative Stress in the Treatment of Chronic Obstructive Pulmonary Disease (COPD): A Comprehensive Review
    Hamad Ghaleb Dailah · 2022 · Molecules
  10. Smoking as a contributing factor for development of polycythemia vera and related neoplasms
    Hans Carl Hasselbalch · 2015 · Leukemia Research
  11. Update on the pathological processes, molecular biology, and clinical utility of N-acetylcysteine in chronic obstructive pulmonary disease
    Hoi Nam Tse, Cee Zhung Steven Tseng · 2014 · International Journal of COPD
  12. Nrf2 is required for normal postnatal bone acquisition in mice
    Jung‐Hyun Kim, Vandana Singhal, Shyam S. Biswal, Rajesh Kumar Thimmulappa, Douglas J. DiGirolamo · 2014 · Bone Research
  13. Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general population
    Mateusz Siedliński, Dirkje Sjoukje Postma, Jolanda M.A. Boer, Gerrit van der Steege, Jan P. Schouten, Henriëtte A. Smit, H. Marike Boezen · 2009 · Respiratory Research
  14. Association of Nrf2 with airway pathogenesis: lessons learned from genetic mouse models
    Hye‐Youn Cho, Steven R. Kleeberger · 2015 · Archives of Toxicology
  15. The Unfolded Protein Response in Chronic Obstructive Pulmonary Disease.
    Steven G. Kelsen · 2016 · Europe PMC (PubMed Central)
  16. Emerging pharmaceutical therapies for COPD
    Sowmya P. Lakshmi, Aravind Reddy, Raju C. Reddy · 2017 · International Journal of COPD
  17. Vitamin E isoform γ-tocotrienol protects against emphysema in cigarette smoke-induced COPD
    Hong Yong Peh, W.S. Daniel Tan, Tze Khee Chan, Chen Wei Pow, Paul S. Foster, W.S. Fred Wong · 2017 · Free Radical Biology and Medicine
  18. Baicalin alleviates hyperglycemia-induced endothelial impairment via Nrf2
    Gen Chen, Xiangjuan Chen, Chao Niu, Xiaozhong Huang, Ning An, Jia Man Sun, Shuai Huang, Weijian Ye, Santie Li, Yingjie Shen et al. · 2018 · Journal of Endocrinology
  19. Sulforaphane increases Nrf2 expression and protects alveolar epithelial cells against injury caused by cigarette smoke extract
    Zongxian Jiao, Jiachen Chang, Jing Li, Dengmei Nie, Huijuan Cui, Dongfang Guo · 2017 · Molecular Medicine Reports
  20. Experimental Therapeutics of Nrf2 as a Target for Prevention of Bacterial Exacerbations in COPD
    Shyam S. Biswal, Rajesh Kumar Thimmulappa, Christopher J. Harvey · 2012 · Proceedings of the American Thoracic Society
  21. Lung injury after cigarette smoking is particle related
    Andrew J. Ghio, Sangani Rahul · 2011 · International Journal of COPD
  22. Zinc Prevents the Development of Diabetic Cardiomyopathy in db/db Mice
    Shudong Wang, Bowei Wang, Yuehui Wang, Qian Tong, Quan Liu, Jian Sun, Yang Zheng, Lu Cai · 2017 · International Journal of Molecular Sciences
  23. Dual anti-oxidant and anti-inflammatory actions of the electrophilic cyclooxygenase-2-derived 17-oxo-DHA in lipopolysaccharide- and cigarette smoke-induced inflammation
    Chiara Cipollina, Serena Di Vincenzo, Stefania Gerbino, Liboria Siena, Mark Gjomarkaj, Elisabetta Pace · 2014 · Biochimica et Biophysica Acta (BBA) - General Subjects
  24. Senescence: Pathogenic Driver in Chronic Obstructive Pulmonary Disease
    Melissa Rivas, Gayatri Gupta, Louis Costanzo, Huma Ahmed, Anne E. Wyman, Patrick M. Geraghty · 2022 · Medicina
  25. Increased endoplasmic reticulum stress and Nrf2 repression in peripheral blood mononuclear cells of patients with stable coronary artery disease
    Chiara Mozzini, Anna Fratta Pasini, Ulisse Garbin, Chiara Stranieri, Andrea Pasini, Paola Vallerio, Luciano Cominacini · 2014 · Free Radical Biology and Medicine
  26. Reactivity of mouse alveolar macrophages to cigarette smoke is strain dependent
    Daniela Vecchio, Beatrice Arezzini, Alessandra Pecorelli, Giuseppe Valacchi, Piero A. Martorana, Concetta Gardi · 2010 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  27. Ursolic acid attenuates cigarette smoke-induced emphysema in rats by regulating PERK and Nrf2 pathways
    Li Lin, Yan Yin, Gang Hou, Dan Han, Jian Kang, Qiuyue Wang · 2017 · Pulmonary Pharmacology & Therapeutics
  28. Corynoline attenuates LPS-induced acute lung injury in mice by activating Nrf2
    Yan Liu, Man Shu Song, Guangfa Zhu, Xi Xin, Keng Li, Chunting Wu, Lixue Huang · 2017 · International Immunopharmacology
  29. Uncovering the Role of Oxidative Imbalance in the Development and Progression of Bronchial Asthma
    Luiz Henrique César Vasconcelos, Sarah Rebeca Dantas Ferreira, Maria da Conceição Correia Silva, Paula Benvindo Ferreira, Iara Leão Luna de Souza, Fabiana de Andrade Cavalcante, Bagnólia Araújo da Silva · 2021 · Oxidative Medicine and Cellular Longevity
  30. COPD lung studies of Nrf2 expression and the effects of Nrf2 activators
    Jian Li, James M. Baker, Andrew Higham, Rajesh D. Shah, Ángeles Montero, Clare M. Murray, Nicky Cooper, Cathy Lucas, Craig Fox, Dave Singh et al. · 2022 · Inflammopharmacology
  31. Endoplasmic Reticulum Stress, NRF2 Signalling and Cardiovascular Diseases in a Nutshell
    Chiara Mozzini, Luciano Cominacini, Ulisse Garbin, Anna Maria Fratta Pasini · 2017 · Current Atherosclerosis Reports
  32. The aging lung: microenvironment, mechanisms, and diseases
    Yanmei Wang, Xuewen Huang, Guofeng Luo, Yunying Xu, Xiqian Deng, Yumeng Lin, Zhanzhan Wang, Shuwei Zhou, Siyu Wang, Haoran Chen et al. · 2024 · Frontiers in Immunology
  33. Nrf2 expression is increased in peripheral blood mononuclear cells derived from mild–moderate ex-smoker COPD patients with persistent oxidative stress
    Anna Maria Fratta Pasini, Marcello Ferrari, Chiara Stranieri, Paola Vallerio, Chiara Mozzini, Ulisse Garbin, Giorgia Zambon, Luciano Cominacini · 2016 · International Journal of COPD
  34. The ageing lung under stress
    Martina Korfei, BreAnne MacKenzie, Silke Meiners · 2020 · European Respiratory Review
  35. Antioxidants in smokers
    Emanuela Astori, Maria Lisa Garavaglia, Graziano Colombo, Lucia Landoni, Nicola Marcello Portinaro, Aldo Milzani, Isabella Dalle‐Donne · 2021 · Nutrition Research Reviews
  36. An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort study
    Hironori Masuko, Tohru Sakamoto, Yoshiko Kaneko, Hiroaki Iijima, Takashi Naito, Emiko Noguchi, Tomomitsu Hirota, Mayumi Tamari, Nobuyuki Hizawa · 2011 · BMC Medical Genetics
  37. Susceptibility of the Aging Lung to Environmental Injury
    Lei Wang, Francis Green, Suzette M. Smiley‐Jewell, Kent E. Pinkerton · 2010 · Seminars in Respiratory and Critical Care Medicine
  38. A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention
    Ruben D. Prange, Marcus Thiedmann, Anita Bhandari, Neha Mishra, Anupam N. Sinha, Robert Häsler, Philip C Rosenstiel, Karin Uliczka, Christina Wagner, Ali Önder Yildirim et al. · 2018 · Aging
  39. Targeting defective pulmonary innate immunity – A new therapeutic option?
    Kylie B. R. Belchamber, Louise Donnelly · 2020 · Pharmacology & Therapeutics
  40. Regulation of Cigarette Smoke (CS)-Induced Autophagy by Nrf2
    Lingxiang Zhu, Erika C. Barret, Yuxue Xu, Zuguo Liu, Aditya Manoharan, Yin Chen · 2013 · PLoS ONE · Retracted
  41. Nrf2 Regulates Chronic Lung Inflammation and B-Cell Responses to Nontypeable Haemophilus influenzae
    Amit Anand Lugade, R. Robert Vethanayagam, Mehrab Nasirikenari, Paul N. Bogner, Brahm H. Segal, Yasmin M. Thanavala · 2011 · American Journal of Respiratory Cell and Molecular Biology
  42. NFE2L2 polymorphisms, mortality, and metabolism in the general population
    Sylwia Marta Figarska, Judith M. Vonk, H. Marike Boezen · 2014 · Physiological Genomics
  43. Nrf2 Is a Protective Factor against Oxidative Stresses Induced by Diesel Exhaust Particle in Allergic Asthma
    Yingji Li, Tomoyuki Kawada, Arata Azuma · 2013 · Oxidative Medicine and Cellular Longevity
  44. Endoplasmic reticulum stress and Nrf2 repression in circulating cells of type 2 diabetic patients without the recommended glycemic goals
    Chiara Mozzini, Ulisse Garbin, Chiara Stranieri, A. Pasini, Erika Solani, Irene Alessandra Tinelli, Luciano Cominacini, Anna Maria Fratta Pasini · 2014 · Free Radical Research
  45. NRF2 in age-related musculoskeletal diseases: Role and treatment prospects
    Xiangyu Zhang, Hengzhen Li, Lin Chen, Yuxiang Wu, Yusheng Li · 2023 · Genes & Diseases
  46. Functional haplotypes in the promoter region of transcription factor Nrf2 in chronic obstructive pulmonary disease.
    Chung‐Ching Hua, Liang‐Che Chang, Jo‐Chi Tseng, Chien‐Ming Chu, Yu‐Chih Liu, Wen-Bin Shieh · 2010 · Europe PMC (PubMed Central)
  47. Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
    Ken‐ichiro Tanaka, Tomoaki Ishihara, Toshifumi Sugizaki, Daisuke Kobayashi, Yasunobu Yamashita, Kayoko Tahara, Naoki Yamakawa, Kumiko Iijima, Kaoru Mogushi, Hiroshi Tanaka et al. · 2013 · Nature Communications
  48. Sulforaphane inhibitsde novosynthesis of IL-8 and MCP-1 in human epithelial cells generated by cigarette smoke extract
    Warren Starrett, David J. Blake · 2011 · Journal of Immunotoxicology
  49. Iron-Regulated Reactive Oxygen Species Production and Programmed Cell Death in Chronic Obstructive Pulmonary Disease
    Kenji Mizumura, Yasuhiro Gon · 2021 · Antioxidants
  50. Innate Immune Modulation in Chronic Obstructive Pulmonary Disease: Moving Closer toward Vitamin D Therapy
    Nele Heulens, Hannelie Korf, Wim Janssens · 2015 · Journal of Pharmacology and Experimental Therapeutics
  51. Aging Enhances Susceptibility to Cigarette Smoke–Induced Inflammation through Bronchiolar Chemokines
    Chinatsu Moriyama, Tomoko Betsuyaku, Yoko Ito, Ichiro Hamamura, Junko Hata, Hiroshi Takahashi, Yasuyuki Nasuhara, Masaharu Nishimura · 2009 · American Journal of Respiratory Cell and Molecular Biology
  52. Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264.7 Cells through Activation of the Nrf2-ARE Pathway
    Shih‐Yu Lee, Po-Yu Chen, Jung‐Chun Lin, Nicholas S. Kirkby, Ching‐Huei Ou, Tsu‐Chung Chang · 2017 · The American Journal of Chinese Medicine
  53. The mechanistic insights of the antioxidant Keap1-Nrf2 pathway in oncogenesis: a deadly scenario
    Anirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan · 2023 · Medical Oncology
  54. Acrolein exposure suppresses antigen-induced pulmonary inflammation
    Page C. Spiess, David I. Kasahara, Aida Habibovic, Milena Hristova, Matthew J. Randall, Matthew E. Poynter, Albert van der Vliet · 2013 · Respiratory Research
  55. Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease
    Irfan Rahman, Vuokko L. Kinnula · 2012 · Expert Review of Clinical Pharmacology
  56. Cellular senescence—an aging hallmark in chronic obstructive pulmonary disease pathogenesis
    Jun Araya, Kazuyoshi Kuwano · 2021 · Respiratory Investigation
  57. Chaperone-Mediated Autophagy Suppresses Apoptosis via Regulation of the Unfolded Protein Response during Chronic Obstructive Pulmonary Disease Pathogenesis
    Yusuke Hosaka, Jun Araya, Yu Fujita, Tsukasa Kadota, Kazuya Tsubouchi, Masahiro Yoshida, Shunsuke Minagawa, Hiromichi Hara, Hironori Kawamoto, Naoaki Watanabe et al. · 2020 · The Journal of Immunology
  58. Indoxyl Sulfate and p-Cresyl Sulfate in Chronic Kidney Disease. Could These Toxins Modulate the Antioxidant Nrf2-Keap1 Pathway?
    Milena Barcza Stockler‐Pinto, Denis P. Fouque, Christophe Olivier Soulage, Marine L. Croze, Denise Mafra · 2014 · Journal of Renal Nutrition
  59. Bronchiolar epithelial catalase is diminished in smokers with mild COPD
    Tomoko Betsuyaku, Satoshi Fuke, Takashi Inomata, Kichizo Kaga, Toshiaki Morikawa, Nao Odajima, Tracy L. Adair-Kirk, Masaharu Nishimura · 2012 · European Respiratory Journal
  60. Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases
    Cuadrado, Antonio, Cazalla, Eduardo, Bach, Anders, Bathish, Boushra, Naidu, Sharadha Dayalan, DeNicola, Gina M., Dinkova-Kostova, Albena T., Fernández-Ginés, Raquel, Grochot-Przeczek, Anna, Hayes, John D. et al. · 2025 · Redox Biology
  61. Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPD
    Venkataramana K. Sidhaye, Janet T. Holbrook, Alyce E. Burke, Kuladeep R. Sudini, Sanjay Sethi, Gerard J. Criner, Jed W. Fahey, Charles S. Berenson, Michael R. Jacobs, Rajesh Kumar Thimmulappa et al. · 2019 · Respiratory Research
  62. Trans-4,4′-dihydroxystilbene ameliorates cigarette smoke-induced progression of chronic obstructive pulmonary disease via inhibiting oxidative stress and inflammatory response
    Tian Wang, Fang Dai, Guo-Hui Li, Xuemei Chen, Yanru Li, Shuqi Wang, Dong‐Mei Ren, Xiao‐Ning Wang, Hong‐Xiang Lou, Bo Zhou et al. · 2019 · Free Radical Biology and Medicine
  63. Red Blood Cells Protect Albumin from Cigarette Smoke–Induced Oxidation
    Graziano Colombo, Ranieri Rossi, Nicoletta Gagliano, Nicola Marcello Portinaro, Marco Clerici, Andrea Annibal, Daniela Giustarini, Roberto Colombo, Aldo Milzani, Isabella Dalle‐Donne · 2012 · PLoS ONE
  64. Markers of anti-oxidant response in tobacco smoke exposed subjects: A data-mining review
    Alessia Comandini, Valeria Marzano, Giacomo Curradi, Giorgio Federici, Andrea Urbani, Cesare Saltini · 2010 · Pulmonary Pharmacology & Therapeutics
  65. Functional Haplotypes in the Promoter Region of Transcription FactorNrf2in Chronic Obstructive Pulmonary Disease
    Chung‐Ching Hua, Liang‐Che Chang, Jo‐Chi Tseng, Chien‐Ming Chu, Yu‐Chih Liu, Wen-Bin Shieh · 2010 · Disease Markers
  66. The anti‐inflammatory effects of PGE2on human lung macrophages are mediated by the EP4receptor
    Sharonjit K Gill, Yiwen Yao, Linda J. Kay, Martin A. Bewley, Helen M. Marriott, Peter T. Peachell · 2016 · British Journal of Pharmacology
  67. Aging affects lipopolysaccharide-induced upregulation of heme oxygenase-1 in the lungs and alveolar macrophages
    Yoko Ito, Tomoko Betsuyaku, Chinatsu Moriyama, Yasuyuki Nasuhara, Masaharu Nishimura · 2008 · Biogerontology
  68. Ilex paraguariensis extracts and its polyphenols prevent oxidative damage and senescence of human retinal pigment epithelium cells
    Pablo S. Tate, Mariela Claudia Marazita, Melisa D. Marquioni‐Ramella, Ángela M. Suburo · 2020 · Journal of Functional Foods
  69. Redox Regulation in Aging Lungs and Therapeutic Implications of Antioxidants in COPD
    Hirofumi Kiyokawa, Yuma Hoshino, Kazuhiro Sakaguchi, Shigeo Muro, Junji Yodoi · 2021 · Antioxidants
  70. Heat-Not-Burn cigarette induces oxidative stress response in primary rat alveolar epithelial cells
    Yoko Ito, Kana Oshinden, Naokata Kutsuzawa, Chinatsu Kohno, Sanae Isaki, Keiko Yokoyama, Tadayuki Sato, Masayuki Tanaka, Koichiro Asano · 2020 · PLoS ONE
  71. Dietary zinc modifies diabetic-induced renal pathology in rats
    Wael M. Elsaed, Hazem Abdelhamid Mohamed · 2016 · Renal Failure
  72. Fenretinide Causes Emphysema, Which Is Prevented by Sphingosine 1-Phoshate
    Masanori Yasuo, Shiro Mizuno, Jeremy C. Allegood, Donatas Kraskauskas, Harm Jan Bogaard, Sarah Spiegel, Norbert Felix Voelkel · 2013 · PLoS ONE
  73. Carbocisteine Reduces Virus-Induced Pulmonary Inflammation in Mice Exposed to Cigarette Smoke
    Yuichi Yageta, Yukio Ishii, Yuko Morishima, Satoshi Ano, Shigeo Ohtsuka, Masashi Matsuyama, Kaoru Takeuchi, Ken Itoh, Masayuki P. Yamamoto, Nobuyuki Hizawa · 2013 · American Journal of Respiratory Cell and Molecular Biology
  74. Guideline for the management of upper respiratory tract infections.
    Adrian John Brink, Mark Frederic Cotton, Charles H. Feldman, Leon Geffen, Willy Hendson, Maurice Hockman, Gary Maartens, Shabir Ahmed Madhi, M Mutua-Mpungu, George H. Swingler · 2004 · PubMed
  75. Role of Nrf2 and exercise in alleviating COPD-induced skeletal muscle dysfunction
    Meiling Jiang, Peijun Li, Yingqi Wang, Yuanyuan Cao, Xiaoyu Han, Linhong Jiang, Xiaodan Liu, Weibing Wu · 2023 · Therapeutic Advances in Respiratory Disease
  76. Cigarette smoke induces pulmonary arterial dysfunction through an imbalance in the redox status of the soluble guanylyl cyclase
    Javier Sevilla‐Montero, Onofre Munar-Rubert, J. Pino-Fadón, Carlota Aguilar-Latorre, Marta Villegas-Esguevillas, B. Climent, Mauro Agrò, Carmen Choya-Foces, Antonio Martı́nez-Ruiz, Eduardo Balsa et al. · 2022 · Free Radical Biology and Medicine
  77. Immunological Basis of Oxidative Stress-Induced Lung Inflammation in Asthma and COPD
    Gurupreet Singh Sethi, Vivek Dharwal, Amarjit Singh Naura · 2019 · Springer eBooks
  78. Antrolone, a Novel Benzoid Derived from Antrodia cinnamomea, Inhibits the LPS-Induced Inflammatory Response in RAW264.7 Macrophage Cells by Balancing the NF-κB and Nrf2 Pathways
    I‐Chuan Yen, Li-Shian Shi, Min-Chieh Chung, Blerina Ahmetaj‐Shala, Tsu‐Chung Chang, Shih‐Yu Lee · 2018 · The American Journal of Chinese Medicine
  79. Large‐scale plasma proteomics can reveal distinct endotypes in chronic obstructive pulmonary disease and severe asthma
    Masaru Suzuki, John Cole, Satoshi Konno, Hironi Makita, Hiroki Kimura, Masaharu Nishimura, Rose A. Maciewicz · 2021 · Clinical and Translational Allergy
  80. Chemical and Physical Approaches to Extend the Replicative and Differentiation Potential of Stem Cells
    Eun Seong Hwang, J. Ok, SeonBeom Song · 2016 · Stem Cell Reviews and Reports
  81. Telomere Length Measurement in Different Ocular Structures: A Potential Implication in Corneal Endothelium Pathogenesis
    Marie‐Catherine Drigeard Desgarnier, Corinne Zinflou, Justin D. Mallet, Sébastien P. Gendron, Sébastien J. Méthot, Patrick J. Rochette · 2016 · Investigative Ophthalmology & Visual Science
  82. BET‐ting on Nrf2: How Nrf2 Signaling can Influence the Therapeutic Activities of BET Protein Inhibitors
    Nirmalya Chatterjee, Dirk Bohmann · 2018 · BioEssays
  83. Oxidative Stress and Antioxidants in Pediatric Asthma’s Evolution and Management
    Ileana Katerina Ioniuc, Ancuta Lupu, Felicia Dragan, Irina Tarnita, Monica Mihaela Alexoae, Violeta Ștreangă, Costică Mitrofan, Aye Aung Thet, Alin Horațiu Nedelcu, Delia Lidia Șalaru et al. · 2024 · Antioxidants
  84. 4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease
    Wenjing Yang, Xuemei Chen, Shuqi Wang, Hui‐Xin Hu, Xin-Ping Cheng, Lin‐Tao Xu, Dong‐Mei Ren, Xiao‐Ning Wang, Baobing Zhao, Hong‐Xiang Lou et al. · 2020 · Journal of Natural Products
  85. Redox-dependent induction of antioxidant defenses by phenolic diterpenes confers stress tolerance in normal human skin fibroblasts: Insights on replicative senescence
    Ana Cristina Carvalho, Andreia Castro Gomes, Cristina Pereira‐Wilson, Cristóvão F. Lima · 2015 · Free Radical Biology and Medicine
  86. Relationship between neutrophil influx and oxidative stress in alveolar space in lipopolysaccharide-induced lung injury
    Takayuki Yoshida, Keita Nagai, Takashi Inomata, Yoko Ito, Tomoko Betsuyaku, Masaharu Nishimura · 2013 · Respiratory Physiology & Neurobiology
  87. Regulation of NRF2, AP‐1 and NF‐κB by cigarette smoke exposure in three‐dimensional human bronchial epithelial cells
    Takashi Sekine, Tadashi Hirata, Shinkichi Ishikawa, Shigeaki Ito, Kanae Ishimori, Kazushi Matsumura, Katsuhiko Muraki · 2018 · Journal of Applied Toxicology
  88. Retinal Microenvironment Imbalance in Dry Age-Related Macular Degeneration: A Mini-Review
    Brad P. Barnett, James T. Handa · 2013 · Gerontology
  89. Mir-29b mediates the regulation of Nrf2 on airway epithelial remodeling and Th1/Th2 differentiation in COPD rats
    Yumin Chi, Qingguo Di, Guangchao Han, Min Li, Baohua Sun · 2019 · Saudi Journal of Biological Sciences
  90. Disruption of Sinonasal Epithelial Nrf2 Enhances Susceptibility to Rhinosinusitis in a Mouse Model
    Murugappan Ramanathan, Anuj Tharakan, Venkataramana K. Sidhaye, Andrew P. Lane, Shyam S. Biswal, Nyall R. London · 2020 · The Laryngoscope
  91. Cigarette smoke induces alterations in the drug-binding properties of human serum albumin
    Marco Clerici, Graziano Colombo, Francesco Secundo, Nicoletta Gagliano, Roberto Colombo, Nicola Marcello Portinaro, Daniela Giustarini, Aldo Milzani, Ranieri Rossi, Isabella Dalle‐Donne · 2014 · Blood Cells Molecules and Diseases
  92. Non-coding RNAs as Regulators of Cellular Senescence in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease
    Norihito Omote, Maor Sauler · 2020 · Frontiers in Medicine
  93. Serum heme oxygenase-1 measurement is useful for evaluating disease activity and outcomes in patients with acute respiratory distress syndrome and acute exacerbation of interstitial lung disease
    Ryo Nagasawa, Yu Hara, Kota Murohashi, Ayako Aoki, Nobuaki Kobayashi, Shigeto Takagi, Satoru Hashimoto, Akihiko Kawana, Takeshi Kaneko · 2020 · BMC Pulmonary Medicine
  94. Nrf-2 as a novel target in radiation induced lung injury
    Yuanyuan Chen, Meng Wang, Chenyang Zuo, Meng-Xia Mao, Xiaochun Peng, Jun Cai · 2024 · Heliyon
  95. A Brief Review of Chronic Obstructive Pulmonary Disease
    James C. Hogg · 2012 · Canadian Respiratory Journal
  96. Bone marrow-derived mesenchymal stem cells ameliorate liver injury in a rat model of sepsis by activating Nrf2 signaling
    Sally A. Selim, Samia Adel Abd El-Baset, Asmaa A. A. Kattaia, Eman M. Askar, Eman Abd Elkader · 2018 · Histochemistry and Cell Biology
  97. Nrf2 and the Nrf2-Interacting Network in Respiratory Inflammation and Diseases
    Jennifer Carlson, Lindsey Price, Huai Deng · 2020 · Progress in inflammation research
  98. DJ-1 modulates Nrf2-mediated MRP1 expression by activating Wnt3a/β-catenin signalling in A549 cells exposed to cigarette smoke extract and LPS
    Jian Zhou, Chuanzong Qi, Xin Hua Fang, Zi‐Hao Wang, Shuyi Zhang, Dalang Li, Jue Song · 2021 · Life Sciences
  99. Charge-switchable, anti-oxidative molecule tuned polyelectrolyte multilayered films: Amplified polyelectrolyte diffusivity and accelerated diabetes wound healing
    Gang Zheng, Di Zhang, Qian Tang, Haiwei Ma, Xiaoyu Dong, Yanlin Chen, Wen-Fei Ni, Bailiang Wang, Huazi Xu, Liyan Shen · 2021 · Chemical Engineering Journal
  100. Dysregulated Nrf2 signaling in response to di(2-ethylhexyl) phthalate in neutrophils of children with autism
    Ahmed Nadeem, Sheikh F. Ahmad, Naif Obaid Al-Harbi, Laila Yousef AL-Ayadhi, Mohammed Mufadhe Alanazi, Ali S. Alfardan, Sabry Mohamed Attia, Mohammad Algahtani, Saleh A. Bakheet · 2022 · International Immunopharmacology