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Biodistribution of Carbon Single-Wall Carbon Nanotubes in Mice
Abstract
Carbon nanotubes are promising for use in biomedical and pharmaceutical sciences. Therefore, it becomes imperative to know the basic biological properties of carbon nanotubes in vivo. We labeled the water-soluble hydroxylated carbon single-wall nanotubes with radioactive 125I atoms, and then the tracer was used to study the distribution of hydroxylated carbon single-wall nanotubes in mice. They moved easily among the compartments and tissues of the body, behaving as small active molecules though their apparent mean molecular weight is tremendously large. This study, for the first time, affords a quantitative analysis of carbon nanotubes accumulated in animal tissues.
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Cited by
Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460
Promises, facts and challenges for carbon nanotubes in imaging and therapeutics
Kostarelos, K., Bianco, A., & Prato, M. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.241 · Cited by 787
Nanotechnology Safety Concerns Revisited
Stern, S. T., & McNeil, S. E. (2008) · Toxicological Sciences · doi:10.1093/toxsci/kfm169 · Cited by 560
Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery
Panwar, N., Soehartono, A. M., Chan, K. K., Zeng, S., Xu, G., Qu, J., Coquet, P., Yong, K.-T., & Chen, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00099 · Cited by 555
Behavior and Toxicity of Graphene and Its Functionalized Derivatives in Biological Systems
Yang, K., Li, Y., Tan, X., Peng, R., & Liu, Z. (2013) · Small · doi:10.1002/smll.201201417 · Cited by 462
Metadata
- Authors
- Wang, H., Wang, J., Deng, X., Sun, H., Shi, Z., Gu, Z., Liu, Y., & Zhaoc, Y.
- Venue
- Journal of Nanoscience and Nanotechnology
- Publisher
- American Scientific Publishers
- Published
- 2004-11-01
- Volume
- 4
- Issue
- 8
- Pages
- 1019-1024
- ISSN
- 1533-4880 (ISSN-L)
- 0000-0000
- OpenAlex
- W1996903255
- Cited by
- 408
- References
- 0
- FWCI
- 9.34
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wang, H., Wang, J., Deng, X., Sun, H., Shi, Z., Gu, Z., Liu, Y., & Zhaoc, Y. (2004). Biodistribution of Carbon Single-Wall Carbon Nanotubes in Mice. Journal of Nanoscience and Nanotechnology. https://doi.org/10.1166/jnn.2004.146
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