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Antimetastatic Effect of an Orally Active Heparin Derivative on Experimentally Induced Metastasis

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Steady plasma concentration of unfractionated heparin reduces infarct volume and prevents inflammatory damage after transient focal cerebral ischemia in the rat

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Anharmonic simulations of the vibrational spectrum of sulfated compounds: application to the glycosaminoglycan fragment glucosamine 6-sulfate

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Vein wall re-endothelialization after deep vein thrombosis is improved with low-molecular-weight heparin

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P-Selectin-mediated Acute Inflammation Can Be Blocked by Chemically Modified Heparin, RO-Heparin

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Evaluation of T cell cytokines and their role in recurrent miscarriage

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Identification of L-selectin Binding Heparan Sulfates Attached to Collagen Type XVIII

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Targeting the P-selectin/PSGL-1 pathway: discovery of disease-modifying therapeutics for disorders of thromboinflammation

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Decorin Potentiates Interferon-γ Activity in a Model of Allergic Inflammation

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Heparin-induced Leukocytosis Requires 6-O-Sulfation and Is Caused by Blockade of Selectin- and CXCL12 Protein-mediated Leukocyte Trafficking in Mice

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Effects of low molecular weight heparin on the polarization and cytokine profile of macrophages and T helper cells in vitro

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Non-Anticoagulant Fractions of Enoxaparin Suppress Inflammatory Cytokine Release from Peripheral Blood Mononuclear Cells of Allergic Asthmatic Individuals

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Clinical Outcomes Associated With the Early Postoperative Use of Heparin in Pancreas Transplantation

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Targeting Host Cell Proteases to Prevent SARS-CoV-2 Invasion

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Shell Cleavable Dendritic Polyglycerol Sulfates Show High Anti‐Inflammatory Properties by Inhibiting L‐Selectin Binding and Complement Activation

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Heparan sulfate inhibitors and their therapeutic implications in inflammatory illnesses

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Heparin and Heparin-Derivatives in Post-Subarachnoid Hemorrhage Brain Injury: A Multimodal Therapy for a Multimodal Disease

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Effects of low molecular weight heparin in obstructed kidneys: decrease of collagen, fibronectin and TGF-β, and increase of chondroitin/dermatan sulfate proteoglycans and macrophage infiltration

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Effect of prednisone, aspirin, low molecular weight heparin and intravenous immunoglobulin on outcome of pregnancy in women with antiphospholipid syndrome

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Selective antimetastatic effect of heparins in preclinical human melanoma models is based on inhibition of migration and microvascular arrest

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Cytokine gene expression and production by human LPS‐stimulated mononuclear cells are inhibited by sulfated heparin‐like semi‐synthetic derivatives

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Nadroparin Sodium Activates Nrf2/HO-1 Pathway in Acetic Acid-Induced Colitis in Rats

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Fucosylated chondroitin sulfate attenuates renal fibrosis in animals submitted to unilateral ureteral obstruction: a P-selectin-mediated event?

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A synthetic heparin-mimicking polyanionic compound inhibits central nervous system inflammation

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Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans

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HS and Inflammation: A Potential Playground for the Sulfs?

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Self-assembling lipid modified glycol-split heparin nanoparticles suppress lipopolysaccharide-induced inflammation through TLR4–NF-κB signaling

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Natural History of Venous Thromboembolism

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Synthesis of the Oligosaccharides Related to Branching Sites of Fucosylated Chondroitin Sulfates from Sea Cucumbers

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Purification and characterisation of a P-selectin-binding molecule from the salivary glands of Ornithodoros moubata that induces protective anti-tick immune responses in pigs

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Use of Heparin in Women With Early and Late Miscarriages With and Without Thrombophilia

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In Vitro Evidences of Heparin’s Effects on Embryo Implantation and Trophoblast Development

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2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity

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Defined Surface Immobilization of Glycosaminoglycan Molecules for Probing and Modulation of Cell–Material Interactions

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Heparin and EDTA as anticoagulant differentially affect cytokine mRNA level of cultured porcine blood cells

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Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses

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Transplantation of Islet-Containing microcapsules modified with constitutional isomers of sulfated alginate in diabetic mice to mitigate fibrosis for Long-term glycemic control

Samsonchi, Z., Karimi, H., Izadi, Z., Baei, P., Najarasl, M., Ashtiani, M. K., Mohammadi, J., Moazenchi, M., Tahamtani, Y., Baharvand, H., et al. (2021) · Chemical Engineering Journal · doi:10.1016/j.cej.2021.134298 · Cited by 27

Long-term Intervention with Heparins in a Rat Model of Peritoneal Dialysis

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Strategies to Overcome Heparins’ Low Oral Bioavailability

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Vein Wall Remodeling after Deep Vein Thrombosis: Differential Effects of Low Molecular Weight Heparin and Doxycycline

Sood, V., Luke, C. E., Miller, E., Mitsuya, M., Upchurch, G. R., Wakefield, T. W., Myers, D. D., & Henke, P. K. (2010) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2009.11.002 · Cited by 27

Purification, characterization and in vivo studies of salmon heparin

Flengsrud, R., Larsen, M. L., & Ødegaard, O. R. (2010) · Thrombosis Research · doi:10.1016/j.thromres.2010.07.004 · Cited by 27

Acute Effect of Standard Heparin Versus Low Molecular Weight Heparin on Oxidative Stress and Inflammation in Hemodialysis Patients

Poyrazoğlu, O. K., Doğukan, A., Yalnız, M., Seçkin, D., & Günal, A. İ. (2006) · Renal Failure · doi:10.1080/08860220600925594 · Cited by 27

Selectin-blocking semisynthetic sulfated polysaccharides as promising anti-inflammatory agents

Höpfner, M., Alban, S., Schumacher, G., Rothe, U., & Bendas, G. (2003) · Journal of Pharmacy and Pharmacology · doi:10.1211/002235703765344621 · Cited by 27

Heparin, Heparan Sulphate and Sepsis: Potential New Options for Treatment

Hogwood, J., Gray, E., & Mulloy, B. (2023) · Pharmaceuticals · doi:10.3390/ph16020271 · Cited by 28

Assays and reference materials for current and future applications of heparins

Mulloy, B., Hogwood, J., & Gray, E. (2010) · Biologicals · doi:10.1016/j.biologicals.2010.02.010 · Cited by 27

Chemically modified heparin inhibits the in vitro adhesion of nonsmall cell lung cancer cells to P-selectin

Gao, Y., Wei, M., Zheng, S., Ba, X., Hao, S., & Zeng, X. (2005) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-005-0061-9 · Cited by 26

Selectively desulfated heparin inhibits P-selectin-mediated adhesion of human melanoma cells

Wei, M., Gao, Y., Tian, M., Li, N., Hao, S., & Zeng, X. (2005) · Cancer Letters · doi:10.1016/j.canlet.2005.01.034 · Cited by 26

In vitro assessment of dual (antiviral and antitumor) activity of a novel lectin produced by the newly cyanobacterium isolate, Oscillatoria acuminate MHM-632 MK014210.1

Saad, M. H., El‐Fakharany, E. M., Salem, M. S., & Sidkey, N. M. (2020) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2020.1848632 · Cited by 25

Heparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1

Farwell, S. L. N., Kanyi, D., Hamel, M., Slee, J. B., Miller, E. A., Cipolle, M. D., & Lowe‐Krentz, L. J. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.681288 · Cited by 25

Sulfated fucans and a sulfated galactan from sea urchins as potent inhibitors of selectin-dependent hematogenous metastasis

Teixeira, F. C. O. B., Kozlowski, E. O., Micheli, K. V., Vilela-Silva, A. C. E. S., Borsig, L., & Pavão, M. S. G. (2018) · Glycobiology · doi:10.1093/glycob/cwy020 · Cited by 24

Mast Cells Exert Anti-Inflammatory Effects in an IL10−/−Model of Spontaneous Colitis

Lennon, E. M., Borst, L. B., Edwards, L., & Moeser, A. J. (2018) · Mediators of Inflammation · doi:10.1155/2018/7817360 · Cited by 26

The inhibition of the integrin VLA-4 in MV3 melanoma cell binding by non-anticoagulant heparin derivatives

Schlesinger, M., Schmitz, P., Zeisig, R., Naggi, A., Torri, G., Casu, B., & Bendas, G. (2011) · Thrombosis Research · doi:10.1016/j.thromres.2011.10.023 · Cited by 24

Heparin inhibits lipopolysaccharide (LPS) binding to leukocytes and LPS‐induced cytokine production

Anastase‐Ravion, S., Blondin, C., Cholley, B., Haeffner‐Cavaillon, N., Castellot, J. J., & Letourneur, D. (2003) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.10604 · Cited by 24

Unfractionated heparin after TBI reduces in vivo cerebrovascular inflammation, brain edema and accelerates cognitive recovery

Nagata, K., Kumasaka, K., Browne, K. D., Li, S., St-Pierre, J., Cognetti, J. S., Marks, J. A., Johnson, V. E., Smith, D. H., & L., J. L. P. (2016) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000001215 · Cited by 24

Prevention of the Postthrombotic Syndrome with Anticoagulation: A Narrative Review

Makedonov, I., Kahn, S. R., Abdulrehman, J., Schulman, S., Delluc, A., Gross, P. L., & Galanaud, J. ‐. (2021) · Thrombosis and Haemostasis · doi:10.1055/a-1711-1263 · Cited by 23

SPR Biosensor Probing the Interactions between TIMP-3 and Heparin/GAGs

Zhang, F., Lee, K., & Linhardt, R. J. (2015) · Biosensors · doi:10.3390/bios5030500 · Cited by 23

The effect of IVX‐0142, a heparin‐derived hypersulfated disaccharide, on the allergic airway responses in asthma

Duong, M. T., Cockcroft, D., Boulet, L. ‐., Ahmed, T., Iverson, H., Atkinson, D. C., Stahl, E. G., Watson, R. M., Davis, B. E., Milot, J., et al. (2008) · Allergy · doi:10.1111/j.1398-9995.2008.01707.x · Cited by 23

Functional role of biofouling linked to aquaculture facilities in Mediterranean enclosed locations

Montalto, V., Rinaldi, A., Ape, F., Mangano, M. C., Gristina, M., Sarà, G., & Mirto, S. (2019) · Aquaculture Environment Interactions · doi:10.3354/aei00339 · Cited by 24

A Non-Anticoagulant Fraction of Heparin Inhibits Leukocyte Diapedesis into the Lung by an Effect on Platelets

Riffo‐Vasquez, Y., Somani, A., Man, F., Amison, R. T., Pitchford, S. C., & Page, C. P. (2016) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2015-0172oc · Cited by 22

Recombinant Heparin—New Opportunities

Glass, C. A. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00341 · Cited by 22

Characterization of the interaction between platelet factor 4 and homogeneous synthetic low molecular weight heparins

Nguyen, T., Xu, Y., Brandt, S. V., Mandelkow, M., Raschke, R., Strobel, U., Delcea, M., Zhou, W., Liu, J., & Greinacher, A. (2019) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14657 · Cited by 22

Direct In Vivo Monitoring of Acute Allergic Reactions in Human Conjunctiva

Helintö, M., Renkonen, R., Tervo, T., Vesaluoma, M. H., Saaren‐Seppälä, H., Haahtela, T., & Kirveskari, J. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.5.3235 · Cited by 22

Multifaceted roles of heparin and its derivatives in inflammation and cancer: Mechanisms, clinical applications, and future directions

Zeng, X., Hou, Y., Luo, L., Ren, L., Wang, Y., Jin, X., Deng, L., Gao, Y., Zhang, D., Huang, J., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.148054 · Cited by 24

Non-anticoagulant derivatives of heparin for the management of asthma: distant dream or close reality?

Shastri, M. D., Peterson, G. M., Stewart, N., Sohal, S. S., & Patel, R. P. (2014) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2014.866092 · Cited by 21

Guidance for the management of patients with vascular disease or cardiovascular risk factors and Covid-19 Position paper from VAS-European Independent Foundation in Angiology/Vascular Medicine

Gerotziafas, G., Dreden, P. V., Catalano, M., Colgan, M. P., Pécsvárady, Z., Wautrecht, J.-C., Fazeli, B., Olinic, D.-M., & Farkas, K. (2020) · Sang thrombose vaisseaux · doi:10.1684/stv.2020.1149 · Cited by 21

Current concepts of platelet activation: possibilities for therapeutic modulation of heterotypic vs. homotypic aggregation

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Control of tissue homeostasis by the extracellular matrix: Synthetic heparan sulfate as a promising therapeutic for periodontal health and bone regeneration

Miguez, P. A., Bash, E., Musskopf, M. L., Tuin, S. A., Rivera-Concepcion, A., Chapple, I., & Liu, J. (2023) · Periodontology 2000 · doi:10.1111/prd.12515 · Cited by 20

Enzymatic Placement of 6-O-Sulfo Groups in Heparan Sulfate

Liu, R., & Liu, J. (2011) · Biochemistry · doi:10.1021/bi200072t · Cited by 20

Efficient selective preparation of methyl-1,2,4-tri-O-acetyl-3-O-benzyl-β-l-idopyranuronate from methyl 3-O-benzyl-l-iduronate

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Beneficial effect of low-molecular-weight heparin against lipopolysaccharide-induced disseminated intravascular coagulation in rats is abolished by coadministration of tranexamic acid

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Nonanticoagulant heparin reduces myocyte Na+and Ca2+loading during simulated ischemia and decreases reperfusion injury

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Mesenteric ischemia-reperfusion injury: Clearly improved hemodynamics but only minor protection of the rat small intestine by (sub)therapeutic heparin sodium and enoxaparin doses

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Hepatic Syndecan-1 Changes Associate With Dyslipidemia After Renal Transplantation

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Ascidian (chordate-tunicate) and mammalian heparin enemas attenuate experimental diversion colitis

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Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis

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Low Molecular Weight Heparin Suppresses Tumor Necrosis Factor Expression from Deep Vein Thrombosis

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NKG2D and CD94 bind to heparin and sulfate-containing polysaccharides

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P-Selectin-mediated Acute Inflammation Can Be Blocked by Chemically Modified Heparin, RO-Heparin

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Heparin oligosaccharides bind L- and P-selectin and inhibit acute inflammation

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Gui, S. (2003) · Shengming kexue

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