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Cited by 235Adrenal Hormones and DisordersEstrogen and related hormone effectsStress Responses and Cortisol

Transcortin: a corticosteroid-binding protein of plasma. II. Levels in various conditions and the effects of estrogens

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Sandberg, Avery A., Slaunwhite, W. Roy·1959·Journal of Clinical Investigation
DOI 10.1172/jci103904PMC PMC442083
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Abstract

3 mos.91 22 P. P.* 2-4 mos.93 23 P. P.* 1-4 mos.90 26 P. P.* 3-4 mos.88 29 W. D. 4 mos.92 30 P. P.* 5 mos.93 28 P. P.* 9-11 mos.96 17 K.B. 1 2/12 yrs.96 21 K. F. 1 5/12 yrs.98 C. N. 1 10/12 yrs.91 P. P.* 1 6/12-2 yrs.98 18 H.R. 3 6/12 yrs.96 21 P. P.* 4 2/12-5 yrs.96 22 C. R. 5 yrs.

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Crossref · 10.1172/jci103904

Cites

23 of 23 references verified0 citation errors · 0 not checkable

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  • Elevated CBG levels are typically seen in hyperestrogenemic states such as pregnancy and with the use of estrogen/progestin-containing combined oral contraceptives.

    “Elevated CBG levels are typically seen in hyperestrogenemic states such as pregnancy and with the use of estrogen/progestin-containing combined oral contraceptives (COCs) (10-12).”

    From Salivary Cortisol and Cortisone Can Circumvent Confounding Effects of Oral Contraceptives in the Short Synacthen Test (2024) · cites this paper as [10]

    The Discussion (page unavailable) reports increased transcortin binding capacity during pregnancy, and the section on estrogen administration reports increased transcortin levels after estrogen treatment. The paper does not address estrogen/progestin-containing combined oral contraceptives specifically, so it does not establish that part of the claim. (LLM, conf=0.88)

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Cites

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Research works printed but not linked: 6

  1. Peterson, R. E., Karrer, A., and Guerra, S. L. Eval- uation of the Silber-Porter procedure for deter- mination of plasma hydrocortisone. Analyt. Chem. 1957, 29, 144.
  2. Migeon, C. J., Bertrand, J., and Wall, P. E. Physi- ological disposition of 4-C'4-cortisol during late pregnancy. J. clin. Invest. 1957, 36, 1350.
  3. Grumbach, M. M., Ducharme, J. R., and Morishima, A. On the metabolism of hydrocortisone and its metabolites in premature and newborn infants. Proc. Soc. Pediat. Res. (Buck Hill Falls, Pa.) May, 1959.
  4. Peterson, R. E. The miscible pool and turn-over rate of corticosteroids. Rec. Progr. Hormone Res. In press.
  5. Martin, J. D., and Mills, I. H. The effect of preg- nancy on adrenal steroid metabolism. Clin. Sci. 1958, 17, 137.
  6. Daughaday, W. H. Binding of corticosteroids by plasma proteins. V. Corticosteroid-binding globu- lin activity in normal human beings and in cer- tain disease states. Arch. intern. Med. 1958, 101, 286. 129)

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Authors
Sandberg, A. A., & Slaunwhite, W. R.
Affiliations
Roswell Park Comprehensive Cancer Center (US)
Venue
Journal of Clinical Investigation
Publisher
American Society for Clinical Investigation
Published
1959-08-01
Volume
38
Issue
8
Pages
1290-1297
ISSN
0021-9738 (ISSN-L)
DOI
10.1172/jci103904
PMC
PMC442083
OpenAlex
W2016551035
Cited by
235
References
23
Citations by year
2024: 2 · 2019: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2012: 1
FWCI
26.54
Type
journal article
Language
en
Open access
Locations
  • Journal of Clinical Investigation (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institutes of Health
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords
corticosteroid-binding globulin, corticosteroid-binding protein, plasma protein levels, estrogen effects, sex hormones, age-related changes
MeSH terms
Adrenal Cortex Hormones, Blood Proteins, Estrogens, Humans, Plasma, Transcortin

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