The DOI matches its Crossref record.
Hormonal control of the renal conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol
Open accessAbstract
Isolated renal tubules from vitamin D-deficient chicks catalyse the in vitro conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. This conversion is stimulated by 5 x 10(-10) M bovine parathyroid hormone, or by 10(-6) M cyclic AMP. It is inhibited by 10(-9) M porcine calcitonin. It is concluded that these hormonal controls of the synthesis of the renal hormone 1,25-dihydroxycholecalciferol are of particular physiological significance in coordinating the activities of the various organs involved in extracellular calcium homeostasis.
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Citations
Cited by
GRAY, R. W., WILZ, D. R., CALDAS, A. E., & LEMANN, J. (1977) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-45-2-299 · Cited by 318
Hollis, B. W., & Wagner, C. L. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2653 · Cited by 293
1,25-Dihydroxyvitamin D3 production by human keratinocytes. Kinetics and regulation.
Bikle, D. D., Nemanic, M. K., Gee, E., & Elias, P. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112609 · Cited by 269
Self-citationPeptides from the calcitonin genes: molecular genetics, structure and function
Breimer, L. H., MacIntyre, I., & Zaidi, M. (1988) · Biochemical Journal · doi:10.1042/bj2550377 · Cited by 189
Metadata
- Authors
- Rasmussen, H., Wong, M., Bikle, D., & Goodman, D. B. P.
- Venue
- Journal of Clinical Investigation
- Published
- 1972-09-01
- Volume
- 51
- Issue
- 9
- Pages
- 2502-2504
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2022909845
- Cited by
- 331
- References
- 0
- FWCI
- 46.84
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Hormonal control of the renal conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. https://app.cochat.ai/papers/10.1172/jci107065
- The paper
- Rasmussen, H., Wong, M., Bikle, D., & Goodman, D. B. P. (1972). Hormonal control of the renal conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol. Journal of Clinical Investigation. https://doi.org/10.1172/jci107065
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
