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Cited by 420

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system.

Open access
Cohen, H J, Chovaniec, M E·1978·Journal of Clinical Investigation

Abstract

Stimulation of guinea pig granolocytes by digitonin results in superoxide (O-2) generation. A continuous assay shows that there is a lag between the addition of digitonin and the onset of O-2 production. The rate of activation of the O-2 generating system is dependent upon the concentration of digitonin and the temperature. The final linear rate of O-2 production is affected by the concentration of digitonin, temperature, pH, and the presence of exogenous reduced pyridine nucleotides. Thus, factors which alter either the activation process or the activity of the O-2 generating system can affect O-2 production by stimulated granolocytes.

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Crossref · 10.1172/jci109007

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Metadata

Authors
Cohen, H. J., & Chovaniec, M. E.
Venue
Journal of Clinical Investigation
Published
1978-04-01
Volume
61
Issue
4
Pages
1081-1087
ISSN
0021-9738 (ISSN-L)
OpenAlex
W2020704694
Cited by
420
References
1
FWCI
8.10
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system. https://app.cochat.ai/papers/10.1172/jci109007
The paper
Cohen, H. J., & Chovaniec, M. E. (1978). Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system. Journal of Clinical Investigation. https://doi.org/10.1172/jci109007

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.