Effect of fatty acids on glucose production and utilization in man.
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- Acute elevation of free fatty acid levels leads to hepatic insulin resistance in obese subjectsStefano Bevilacqua, Riccardo C. Bonadonna, Giuseppe Buzzigoli, Claudio De Boni, Demetrio Ciociaro, Franco Maccari, Maria Antonietta Giorico, Eleuterio Ferrannini · 1987 · Metabolism
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- The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: results of the Paris Prospective StudyMarie-Aline A Charles, É. Eschwège, Nadine Thibult, Jean‐Roger Claude, Jean‐Michel Warnet, G Rosselin, Jean R Girard, Beverley Balkau · 1997 · Diabetologia
- Factor analysis of the metabolic syndrome: obesity vs insulin resistance as the central abnormalityPJ Anderson, J. A. J. H. Critchley, JCN Chan, CS Cockram, Z. S. K. Lee, G. Neil Thomas, Brian Tomlinson · 2001 · International Journal of Obesity
- Tissue triglycerides, insulin resistance, and insulin production: implications for hyperinsulinemia of obesityKazunori Koyama, Guoxun Chen, Young Lee, Roger H. Unger · 1997 · American Journal of Physiology-Endocrinology and Metabolism
- Effect of Pioglitazone on Circulating Adipocytokine Levels and Insulin Sensitivity in Type 2 Diabetic PatientsYoshinori Miyazaki, Archana Mahankali, Estela Wajcberg, Mandeep Singh Bajaj, Lawrence J. Mandarino, Ralph Anthony DeFronzo · 2004 · The Journal of Clinical Endocrinology & Metabolism
- Insulin sensitivity, insulin secretion, and metabolic and hormonal parameters in healthy women and women with polycystic ovarian syndromeLaure C. Morin-Papunen, Ilkka Vauhkonen, Riitta M. Koivunen, A Ruokonen, Juha S. Tapanainen · 2000 · Human Reproduction
- Hypocaloric high-protein diet improves glucose oxidation and spares lean body mass: Comparison to hypocaloric high-carbohydrate dietPier Marco Piatti, L.D. Monti, Fulvio Magni, Isabella Fermo, L. Baruffaldi, R. M. Nasser, G. Santambrogio, Maria Cristina Librenti, Marzia Galli-Kienle, Antonio Ettore Pontiroli et al. · 1994 · Metabolism
- Interaction between free fatty acids and glucose metabolismGuenther H. Boden · 2002 · Current Opinion in Clinical Nutrition & Metabolic Care
- Resistant Starch from High-Amylose Maize Increases Insulin Sensitivity in Overweight and Obese MenKevin Carl Maki, Christine Pelkman, E. Terry Finocchiaro, Kathleen Kelley, Andrea L. Lawless, Arianne L. Schild, Tia M. Rains · 2012 · Journal of Nutrition
- Serum lipoprotein lipid profile in women with the polycystic ovary syndrome: relation to anthropometric, endocrine and metabolic variablesJan Holte, Torbjörn Bergh, Christian Berne, Hans Lithell · 1994 · Clinical Endocrinology
- Insulin and Insulin Receptors in Adipose Tissue DevelopmentAngelo Cignarelli, Valentina Annamaria Genchi, Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Francesco Giorgino · 2019 · International Journal of Molecular Sciences
- Adipose tissue and the insulin resistance syndromeKeith N. Frayn · 2001 · Proceedings of The Nutrition Society
- Neck circumference as a simple tool for identifying the metabolic syndrome and insulin resistance: results from the Brazilian Metabolic Syndrome StudyChristiane França Camargo Stabe, Ana Carolina Junqueira Vasques, Marcelo Miranda de Oliveira Lima, Marcos Antônio Tambascia, José Carlos Pareja, Ademar Yamanaka, Bruno Geloneze · 2012 · Clinical Endocrinology
- Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus.Kelley, D E, Mandarino, L J · 1990 · Journal of Clinical Investigation
- Relationship of Anterior and Posterior Subcutaneous Abdominal Fat to Insulin Sensitivity in Nondiabetic MenAnoop Misra, Abhimanyu Garg, Nicola I. Abate, Ronald M. Peshock, James Stray‐Gundersen, Scott M. Grundy · 1997 · Obesity Research
- Cardiovascular disease risk factors as predictors of Type 2 (non-insulin-dependent) diabetes mellitus in elderly subjectsLeena Mykkänen, Johanna Kuusisto, Kalevi Pyörälà, Markku Laakso · 1993 · Diabetologia
- Central Role of the Adipocyte in the Metabolic SyndromeBergman, Richard N., Van Citters, Gregg W., Mittelman, Steven D., Dea, Melvin K., Hamilton-Wessler, Marianthe, Kim, Stella P., Ellmerer, Martin · 2001 · Journal of Investigative Medicine
- How to Measure Adipose Tissue Insulin SensitivityEsben Søndergaard, Ana E. Espinosa De Ycaza, Maria E. Morgan-Bathke, Michael D. Jensen · 2017 · The Journal of Clinical Endocrinology & Metabolism
- Hepatic glucose metabolism in humans—its role in health and diseaseRoden, Michael, Bernroider, Elisabeth · 2003 · Best Practice & Research Clinical Endocrinology & Metabolism
- Prevalence and Predictors of Asymptomatic Liver Disease in Patients Undergoing Gastric Bypass SurgeryCharles H. Beymer · 2003 · Archives of Surgery
- Glucose fatty acid interactions and the regulation of glucose disposalPhilip John Randle, David A. Priestman, Sharad C. Mistry, Antony Halsall · 1994 · Journal of Cellular Biochemistry
- Glycerol production in subcutaneous adipose tissue in lean and obese humans.Per‐Anders Jansson, Annhild Larsson, Ulf Smith, Peter Lönnroth · 1992 · Journal of Clinical Investigation
- Genistein and daidzein modulate hepatic glucose and lipid regulating enzyme activities in C57BL/KsJ-db/db miceSun Ae Park, Myung‐Sook Choi, Soo-Yeul Cho, Jung‐Sook Seo, Un Ju Jung, Myung‐Joo Kim, Mi‐Kyung Sung, Yong Bok Park, Mi‐Kyung Lee · 2006 · Life Sciences
- DNA methylation in the pathogenesis of type 2 diabetes in humansCajsa Davegårdh, Sonia García-Calzón, Karl Bacos, Charlotte Ling · 2018 · Molecular Metabolism
- A look inside the diabetic brain: Contributors to diabetes-induced brain agingWrighten, Shayna A., Piroli, Gerardo G., Grillo, Claudia A., Reagan, Lawrence P. · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Free Fatty Acid Levels Modulate Microvascular Functionde Jongh, Renate T., Serné, Erik H., IJzerman, Richard G., de Vries, Greetje, Stehouwer, Coen D.A. · 2004 · Diabetes
- Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-δLam, Tony K. T., Yoshii, Hidenori, Haber, C. Andrew, Bogdanovic, Elena, Lam, Loretta, Fantus, I. George, Giacca, Adria · 2002 · American Journal of Physiology-Endocrinology and Metabolism
- Pathogenesis and pathophysiology of the cardiometabolic syndromeKirk, Erik P., Klein, Samuel · 2009 · The Journal of Clinical Hypertension
- Interorgan Metabolic Crosstalk in Human Insulin ResistanceSofiya Gancheva, Tomáš Jeleník, Elisa Álvarez-Hernández, Michael Roden · 2018 · Physiological Reviews
- The role of the growth hormone–insulin‐like growth factor axis in glucose homeostasisRichard I. G. Holt, Helen Simpson, P H Sönksen · 2003 · Diabetic Medicine
- Nonalcoholic fatty liver diseaseMarcin Jan Krawczyk, Leonilde Bonfrate, Piero Portincasa · 2010 · Best Practice & Research Clinical Gastroenterology
- The effects of growth hormone on adipose tissue: old observations, new mechanismsJohn Joseph Kopchick, Darlene E. Berryman, Vishwajeet Puri, Kevin Y. Lee, Jens Otto Lunde Jørgensen · 2019 · Nature Reviews Endocrinology
- Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolismJean‐Sébastien Joyal, Marin L. Gantner, Lois E. H. Smith · 2017 · Progress in Retinal and Eye Research
- Targeting fatty acid metabolism to improve glucose metabolismStinkens, R., Goossens, G. H., Jocken, J. W. E., Blaak, E. E. · 2015 · Obesity Reviews
- Effect of a Sustained Reduction in Plasma Free Fatty Acid Concentration on Intramuscular Long-Chain Fatty Acyl-CoAs and Insulin Action in Type 2 Diabetic PatientsBajaj, Mandeep, Suraamornkul, Swangjit, Romanelli, Anthony, Cline, Gary W., Mandarino, Lawrence J., Shulman, Gerald I., DeFronzo, Ralph A. · 2005 · Diabetes
- Role of free fatty acids and insulin in determining free fatty acid and lipid oxidation in man.Per‐Henrik Groop, Riccardo C. Bonadonna, Myron L shank, Alexander S. Petrides, Ralph A. DeFronzo · 1991 · Journal of Clinical Investigation
- Pathophysiology of prediabetesFerrannini, Ele, Gastaldelli, Amalia, Iozzo, Patricia · 2011 · Medical Clinics of North America
- Value of triglyceride-glucose index for the estimation of ischemic stroke risk: Insights from a general populationWenrui Shi, Liying Xing, Jing Li, Yuanmeng Tian, Han Yan, Qun Sun, Dong Dai, Lei Shi, Shuang Liu · 2019 · Nutrition Metabolism and Cardiovascular Diseases
- Carbohydrate fermentation decreases hepatic glucose output in healthy subjectsThorburn, Anne, Muir, Jane, Proietto, Joseph · 1993 · Metabolism
- A Polymorphism in the Human Intestinal Fatty Acid Binding Protein Alters Fatty Acid Transport across Caco-2 CellsLeslie J. Baier, Clifton Bogardus, James C. Sacchettini · 1996 · Journal of Biological Chemistry
- Basal- and insulin-stimulated substrate metabolism in patients with active acromegaly before and after adenomectomyNiels Møller, O. Schmitz, JOL Joorgensen, Jens Astrup, J. F. Bak, Stig Engkjaer Christensen, K. G. M. M. Alberti, J. Weeke · 1992 · The Journal of Clinical Endocrinology & Metabolism
- Rationale and Application of Fatty Acid Oxidation Inhibitors in Treatment of Diabetes MellitusJames Edward Foley · 1992 · Diabetes Care
- Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglyceridesMelania Manco, Antonio Greco, Esmeralda Capristo, Donatella Gniuli, Andrea De Gaetano, Antonio Gasbarrini · 2000 · Metabolism
- Insulin resistance and hyperinsulinemia in patients with chronic congestive heart failureGiuseppe Paolisso, S. De Riu, Giuseppe Marrazzo, Mario Verza, Michele Varricchio, Felice D’Onofrio · 1991 · Metabolism
- Is Visceral Fat Involved in the Pathogenesis of the Metabolic Syndrome? Human ModelMichael D. Jensen · 2006 · Obesity
- Insulin resistance and the sympathetic nervous systemBrent M. Egan · 2003 · Current Hypertension Reports
- Obesity, inflammation and endothelial dysfunction.Micaela Iantorno, Umberto Campia, Nicola Di Daniele, Steven Paul Nisticò, GB. Forleo, Carmine Cardillo, Manfredi Tesauro · 2014 · PubMed
- Fasting Until Noon Triggers Increased Postprandial Hyperglycemia and Impaired Insulin Response After Lunch and Dinner in Individuals With Type 2 Diabetes: A Randomized Clinical TrialDaniela J. Jakubowicz, Julio Wainstein, Bo Åhrén, Zohar Landau, Yosefa Bar‐Dayan, Oren Froy · 2015 · Diabetes Care
- Lipids and Glucose in Type 2 DiabetesGuenther H. Boden, Markku Laakso · 2004 · Diabetes Care
- Total-body and myocardial substrate oxidation in congestive heart failureGiuseppe Paolisso, Antonio Gambardella, Domenico Galzerano, Annamaria D’Amore, Paolo Rubino, Mario Verza, Paola Teasuro, Michele Varricchio, Felice D’Onofrio · 1994 · Metabolism
- Decreased Susceptibility to Fatty Acid–Induced Peripheral Tissue Insulin Resistance in WomenFrias, Juan P., Macaraeg, Gina B., Ofrecio, Jachelle, Yu, Joseph G., Olefsky, Jerrold M., Kruszynska, Yolanta T. · 2001 · Diabetes
- Phenotypic expression of heterozygous lipoprotein lipase deficiency in the extended pedigree of a proband homozygous for a missense mutation.Daniel E. Wilson, Mitsuru Emi, Per‐Henrik Iverius, Akira Hata, L L Wu, Elaine Hillas, R R Williams, Jean-Marc Lalouel · 1990 · Journal of Clinical Investigation
- The Effect of a Plant-Based Low-Carbohydrate (“Eco-Atkins”) Diet on Body Weight and Blood Lipid Concentrations in Hyperlipidemic SubjectsJenkins, David J. A., Wong, Julia M. W., Kendall, Cyril W. C., Esfahani, Amin, Ng, Vivian W. Y., Leong, Tracy C. K., Faulkner, Dorothea A., Vidgen, Ed, Greaves, Kathryn A., Paul, Gregory et al. · 2009 · Archives of Internal Medicine
- Triglyceride Glucose Index and Prognosis of Patients With Ischemic StrokeYimo Zhou, Yuesong Pan, Hongyi Yan, Yilong Wang, Zixiao Li, Xingquan Zhao, Hao Li, Xia Meng, Chunxue Wang, Liping Liu et al. · 2020 · Frontiers in Neurology
- Mechanisms modifying glucose oxidation in diabetes mellitusP J Randle, David A. Priestman, Sharad C. Mistry, Antony Halsall · 1994 · Diabetologia
- Free Fatty Acids Link Metabolism and Regulation of the Insulin-Sensitizing Fibroblast Growth Factor-21Knut Mai, Janin Andres, Katrin Biedasek, Jessica Weicht, Thomas Bobbert, Markus Sabath, Sabine Meinus, Franziska Reinecke, Matthias Möhlig, Martin O. Weickert et al. · 2009 · Diabetes
- Metabolism of adipose tissue in intraabdominal depots in severely obese men and womenM Rebuffé-Scrive, Brian M. Anderson, Lars C. Olbe, Per A Björntorp · 1990 · Metabolism
- Lipid Infusion Impairs Physiologic Insulin-Mediated Capillary Recruitment and Muscle Glucose Uptake In VivoLucy H. Clerk, Stephen Rattigan, Michael G. Clark · 2002 · Diabetes
- Sex Differences in Visceral Fat Lipolysis and Metabolic Complications of ObesityFredrik Lönnqvist, Anders Thörne, V. Large, Peter Arner · 1997 · Arteriosclerosis Thrombosis and Vascular Biology
- Subchronic sleep restriction causes tissue-specific insulin resistanceRao, Madhu N., Neylan, Thomas C., Grunfeld, Carl, Mulligan, Kathleen, Schambelan, Morris, Schwarz, Jean-Marc · 2015 · The Journal of Clinical Endocrinology & Metabolism
- Metabolic benefits deriving from chronic vitamin C supplementation in aged non-insulin dependent diabetics.Giuseppe Paolisso, Vinicio Balbi, C Volpe, Gina Varricchio, Antonio Gambardella, Franco Saccomanno, Stefania Ammendola, Michele Varricchio, Federica D'Onofrio · 1995 · Journal of the American College of Nutrition
- Fat metabolism in human obesityPeter J. Campbell, M. G. Carlson, Nurjahan Nurjhan · 1994 · American Journal of Physiology-Endocrinology and Metabolism
- Free Fatty Acids—The Link Between Obesity and Insulin ResistanceGuenther H. Boden · 2001 · Endocrine Practice
- Effect of short-term fasting on lipid kinetics in lean and obese womenJeffrey F. Horowitz, Simon W. Coppack, Deanna S. Paramore, Philip E. Cryer, Guohong Zhao, Samuel Klein · 1999 · American Journal of Physiology-Endocrinology and Metabolism
- Plasma Free Fatty Acid Concentration as a Modifiable Risk Factor for Metabolic DiseaseHenderson, Gregory C. · 2021 · Nutrients
- Fatty acids and insulin resistance in muscle and liverPeter Louis Kovacs, Michael Stümvoll · 2005 · Best Practice & Research Clinical Endocrinology & Metabolism
- Revisiting the Role of Fat Mass in the Life Extension Induced by Caloric RestrictionNir Barzilai, Gaurav Gupta · 1999 · The Journals of Gerontology Series A
- Relationship between insulin-mediated glucose disposal and lipid metabolism in man.Lillioja, S, Bogardus, C, Mott, D M, Kennedy, A L, Knowler, W C, Howard, B V · 1985 · Journal of Clinical Investigation
- Effect of physiologic hyperinsulinemia on glucose and lipid metabolism in cirrhosis.Alexander S. Petrides, Per‐Henrik Groop, Caroline A. Riely, Ralph A. DeFronzo · 1991 · Journal of Clinical Investigation
- High Prevalence of Polycystic Ovaries and Associated Clinical, Endocrine, and Metabolic Features in Women with Previous Gestational Diabetes MellitusJan Holte, Gianluca Gennarelli, LEIF E. WIDE, Hans Lithell, Christian Berne · 1998 · The Journal of Clinical Endocrinology & Metabolism
- Free fatty acids FFA a link between obesity and insulin resistanceGuenther H. Boden · 1998 · Frontiers in bioscience
- Relationships between plasma-free fatty acid concentration, endogenous glucose production, and fasting hyperglycemia in normal and non-insulin-dependent diabetic individualsAlain Golay, Arthur Swislocki, Yii‐Der Ida Chen, Gerald M. Reaven · 1987 · Metabolism
- Breakfast Consumption Affects Appetite, Energy Intake, and the Metabolic and Endocrine Responses to Foods Consumed Later in the Day in Male Habitual Breakfast EatersNerys M. Astbury, Moira A. Taylor, Ian Andrew Macdonald · 2011 · Journal of Nutrition
- Disturbances in insulin secretion and sensitivity in women with the polycystic ovary syndromeJan Holte · 1996 · Baillière s Clinical Endocrinology and Metabolism
- Exercise Induces Tissue-Specific Adaptations to Enhance Cardiometabolic HealthAshcroft, Stephen P., Stocks, Ben, Egan, Brendan, Zierath, Juleen R. · 2024 · Cell Metabolism
- Regulation of fat-carbohydrate interaction in skeletal muscle during intense aerobic cyclingDavid J. Dyck, Charles T. Putman, George J. F. Heigenhauser, E. Hultman, Lawrence L. Spriet · 1993 · American Journal of Physiology-Endocrinology and Metabolism
- Bromocriptine improves glycaemic control and serum lipid profile in obese Type 2 diabetic subjects: a new approach in the treatment of diabetesAnthony H. Cincotta, ALBERT H. MEIER, M. Cincotta · 1999 · Expert Opinion on Investigational Drugs
- PPARγ activators improve glucose homeostasis by stimulating fatty acid uptake in the adipocytesGeneviève Martin, Kristina Schoonjans, Bart Staels, Johan H. Auwerx · 1998 · Atherosclerosis
- The metabolic syndromeTamàs Fülöp, Daniel Tessier, André C. Carpentier · 2006 · Pathologie Biologie
- Rosiglitazone Improves Downstream Insulin Receptor Signaling in Type 2 Diabetic PatientsYoshinori Miyazaki, Helen He, Lawrence J. Mandarino, Ralph Anthony DeFronzo · 2003 · Diabetes
- Contribution of cortisol to glucose counterregulation in humansDe Feo, P., Perriello, G., Torlone, E., Ventura, M. M., Fanelli, C., Santeusanio, F., Brunetti, P., Gerich, J. E., Bolli, G. B. · 1989 · American Journal of Physiology-Endocrinology and Metabolism
- Dietary polyunsaturated fatty acid regulation of gene transcriptionDonald Β. Jump, Steven D. Clarke, Annette P. Thelen, Marya B. Liimatta, Bing Ren, Maria V. Badin · 1996 · Progress in Lipid Research
- Hyperglycemic Stress and Carbon Stress in Diabetic GlucotoxicityXiaoting Luo, Jinzi Wu, Siqun Jing, Liang‐Jun Yan · 2016 · Aging and Disease
- Childhood Obesity, Adipose Tissue Distribution, and the Pediatric PractitionerArnold H. Slyper · 1998 · PEDIATRICS
- Reversibility of insulin resistance in obese diabetic patients: role of plasma lipidsGeltrude Mingrone, Andrea De Gaetano, A. V. Greco, Esmeralda Capristo, Giuseppe Benedetti, Marco Castagneto, Antonio Gasbarrini · 1997 · Diabetologia
- Glucose metabolism in cirrhosis: A review with some perspectives for the futureAlexander S. Petrides, Ralph A. DeFronzo · 1989 · Diabetes/Metabolism Reviews
- Relationship between lipoprotein levels and in vivo insulin action in normal young white menAbhimanyu Garg, J. Harold Helderman, Michael Koffler, R.M.aPérez Ayuso, Julio Rosenstock, Philip Raskin · 1988 · Metabolism
- Energy expenditure, sex, and endogenous fuel availability in humansNielsen, Søren, Guo, ZengKui, Albu, Jeanine B., Klein, Samuel, O’Brien, Peter C., Jensen, Michael D. · 2003 · Journal of Clinical Investigation
- Lipid Metabolism in MuscleGer J. Vusse, Robert S. Reneman · 1996 · Comprehensive physiology
- Plasma leptin is associated with insulin resistance independent of age, body mass index, fat mass, lipids, and pubertal development in nondiabetic adolescentsK-C Huang, Ruby C.Y. Lin, Nic Kormas, L-T Lee, C-Y Chen, T. P. Gill, Ian Douglas Caterson · 2004 · International Journal of Obesity
- Induction of Hepatic Glucose-6-Phosphatase Gene Expression by Lipid InfusionDuna Massillon, Nir Barzilai, Meredith A. Hawkins, Dina Prus-Wertheimer, Luciano Rossetti · 1997 · Diabetes
- L-Carnitine Improves Glucose Disposal in Type 2 Diabetic PatientsMingrone, Geltrude, Greco, Aldo V., Capristo, Esmeralda, Benedetti, Giuseppe, Giancaterini, Annalisa, Gaetano, Andrea De, Gasbarrini, Giovanni · 1999 · Journal of the American College of Nutrition
- PPAR∞ AND GLUCOSE HOMEOSTASISJohan H. Auwerx · 2002
- Metabolic Adaptations to Dexamethasone‐Induced Insulin Resistance in Healthy VolunteersNicod, Nathalie, Giusti, Vittorio, Besse, Christine, Tappy, Luc · 2003 · Obesity Research
- Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 DiabetesFredirick L. Mashili, Alexander Chibalin, Anna Krook, Juleen Rae Zierath · 2012 · Diabetes
- Defective Fatty Acid-mediated β-Cell Compensation in Zucker Diabetic Fatty RatsHiroshi Hirose, Young H. Lee, Lindsey R. Inman, Yoshitaka Nagasawa, John H. Johnson, Roger H. Unger · 1996 · Journal of Biological Chemistry
- Reversibility of decreased insulin-stimulated glucose transport capacity in diabetic muscle with in vitro incubation. Insulin is not required.Harriet Wallberg‐Henriksson, N. ZETAN, Jan Henriksson · 1987 · Journal of Biological Chemistry
- Systemic and regional free fatty acid metabolism in type 2 diabetesBasu, Ananda, Basu, Rita, Shah, Pankaj, Vella, Adrian, Rizza, Robert A., Jensen, Michael D. · 2001 · American Journal of Physiology-Endocrinology and Metabolism
- Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus.Vaag, A, Skött, P, Damsbo, P, Gall, M A, Richter, E A, Beck-Nielsen, H · 1991 · Journal of Clinical Investigation