The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
The insulin receptor and the molecular mechanism of insulin action.
Open accessAbstract
In humans and most other vertebrates, the primary hormone involved in control of blood glucose is insulin. Insulin acts on cells to stimulate glucose, protein, and lipid metabolism, as well as RNA and DNA synthesis, by modifying the activity of a variety of enzymes and transport processes. The importance of understanding insulin action is not limited to simply satisfying the intellectual needs of the curious biochemist or cell biologist. Elucidating the molecular pathways of insulin action forms an important cornerstone upon which to unravel the pathogenesis of non-insulin-dependent (type II) diabetes mellitus and a major component of other insulin-resistant states including obesity, uremia, glucocorticoid, and growth hormone excess, as well as a variety of rarer genetic disorders such as leprechaunism, the type A syndrome of insulin resistance, and lipoatrophic diabetes.
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Cites
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
Ullrich, A., Bell, J. R., Chen, E. Y., Herrera, R., Petruzzelli, L. M., Dull, T. J., Gray, A., Coussens, L., Liao, Y.-C., Tsubokawa, M., et al. (1985) · Nature · doi:10.1038/313756a0 · Cited by 2,251
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
Ebina, Y., Ellis, L., Jarnagin, K., Edery, M., Graf, L., Clauser, E., Ou, J.-H., Masiarz, F., Kan, Y. W., Goldfine, I. D., et al. (1985) · Cell · doi:10.1016/0092-8674(85)90334-4 · Cited by 1,477
Insulin Stimulates the Phosphorylation of the 95,000-Dalton Subunit of Its Own Receptor
Kasuga, M., Karlsson, F. A., & Kahn, C. R. (1982) · Science · doi:10.1126/science.7031900 · Cited by 1,126
Self-citationEllis, L., Clauser, E., Morgan, D. O., Edery, M., Roth, R. A., & Rutter, W. J. (1986) · Cell · doi:10.1016/0092-8674(86)90786-5 · Cited by 1,070
Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells
White, M. F., Maron, R., & Kahn, C. R. (1985) · Nature · doi:10.1038/318183a0 · Cited by 651
Self-citationKaplan, D. R., Whitman, M., Schaffhausen, B., Pallas, D. C., White, M., Cantley, L., & Roberts, T. M. (1987) · Cell · doi:10.1016/0092-8674(87)90168-1 · Cited by 646
Self-citationChou, C. K., Dull, T. J., Russell, D. S., Gherzi, R., Lebwohl, D., Ullrich, A., & Rosen, O. M. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75716-0 · Cited by 640
Freychet, P., Roth, J., & Neville, D. M. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.8.1833 · Cited by 498
White, M. F., Shoelson, S. E., Keutmann, H., & Kahn, C. R. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)69163-x · Cited by 476
Self-citationSugimoto, Y., Whitman, M., Cantley, L. C., & Erikson, R. L. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.7.2117 · Cited by 462
Cited by
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
Sun, X. J., Rothenberg, P., Kahn, C. R., Backer, J. M., Araki, E., Wilden, P. A., Cahill, D. A., Goldstein, B. J., & White, M. F. (1991) · Nature · doi:10.1038/352073a0 · Cited by 1,574
Self-citationThe pathogenesis and pathophysiology of type 1 and type 2 diabetes mellitus
Ozougwu, O. (2013) · Journal of Physiology and Pathophysiology · doi:10.5897/jpap2013.0001 · Cited by 654
Heffetz, D., Bushkin, I., Dror, R., & Zick, Y. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39885-0 · Cited by 429
Expression and function of IRS-1 in insulin signal transmission.
Sun, X. J., Miralpeix, M., Myers, M. G., Glasheen, E. M., Backer, J. M., Kahn, C. R., & White, M. F. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41723-1 · Cited by 326
Self-citationQin, B., Nagasaki, M., Ren, M., Bajotto, G., Oshida, Y., & Sato, Y. (2003) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(03)00173-6 · Cited by 298
Metadata
- Authors
- Kahn, C. R., & White, M. F.
- Venue
- Journal of Clinical Investigation
- Published
- 1988-10-01
- Volume
- 82
- Issue
- 4
- Pages
- 1151-1156
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2132647577
- Cited by
- 432
- References
- 72
- FWCI
- 11.56
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
