The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Conditional gene targeting.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Here we report the development of an artificial DNA recombination locus (termed Polylox) that enables broadly applicable endogenous barcoding based on the Cre-loxP recombination system6,7.”
From Polylox barcoding reveals haematopoietic stem cell fates realized in vivo (2017) · cites this paper as [7]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Gu, H., Zou, Y.-R., & Rajewsky, K. (1993) · Cell · doi:10.1016/0092-8674(93)90644-6 · Cited by 989
Self-citationMetzger, D., Clifford, J., Chiba, H., & Chambon, P. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.15.6991 · Cited by 570
Research works printed but not linked: 7
- Wu, H., X. Liu, and R. Jaenisch. 1994. Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by ho- mologous recombination in embryonic stem cells. Proc. Natl. Acad. Sci. USA. 91:2819-2823.
- Hoess, R.H., M. Ziese, and N. Sternberg. 1982. P1 site-specific recombi- nation: nucleotide sequence of the recombining sites. Proc. Natl. Acad. Sci. USA. 79:3398-3402.
- Sauer, B., and N. Henderson. 1988. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA. 85:5166-5170.
- Orban, P.C., D. Chui, and J.D. Marth. 1992. Tissue-and site-specific DNA recombination in transgenic mice. Proc. Natl. Acad. Sci. USA. 89:6861- 6865.
- Lakso, M., B. Sauer, B. Mosinger, Jr., E.J. Lee, R.W. Manning, S.H. Yu, K.L. Mulder, and H. Westphal. 1992. Targeted oncogene activation by site-spe- cific recombination in transgenic mice. Proc. Natl. Acad. Sci. USA. 89:6232- 6236.
- Hennet, T., F.K. Hagen, L.A. Tabak, and J.D. Marth. 1995. T-cell-spe- cific deletion of a polypeptide N -acetylgalactosaminyl-transferase gene by site- directed recombination. Proc. Natl. Acad. Sci. USA. 92:12070-12074.
- Furth, P.A., L. St. Onge, H. Böger, P. Gruss, M. Gossen, A. Kistner, H. Bujard, and L. Henninghausen. 1994. Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc. Natl. Acad. Sci. USA. 91:9302-9306.
Cited by
Marino, S., Vooijs, M., van der Gulden, H., Jonkers, J., & Berns, A. (2000) · Genes & Development · doi:10.1101/gad.14.8.994 · Cited by 920
Essential role of brain-derived neurotrophic factor in adult hippocampal function
Monteggia, L. M., Barrot, M., Powell, C. M., Berton, O., Galanis, V., Gemelli, T., Meuth, S., Nagy, A., Greene, R. W., & Nestler, E. J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402141101 · Cited by 685
Takeda, K., Kaisho, T., Yoshida, N., Takeda, J., Kishimoto, T., & Akira, S. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.9.4652 · Cited by 584
Polylox barcoding reveals haematopoietic stem cell fates realized in vivo
Pei, W., Feyerabend, T. B., Rössler, J., Wang, X., Postrach, D., Busch, K., Rode, I., Klapproth, K., Dietlein, N., Quedenau, C., et al. (2017) · Nature · doi:10.1038/nature23653 · Cited by 443
Langenbach, R., Loftin, C., Lee, C., & Tiano, H. (1999) · Biochemical Pharmacology · doi:10.1016/s0006-2952(99)00158-6 · Cited by 230
Metadata
- Authors
- Rajewsky, K., Gu, H., Kühn, R., Betz, U. A., Müller, W., Roes, J., & Schwenk, F.
- Venue
- Journal of Clinical Investigation
- Published
- 1996-08-01
- Volume
- 98
- Issue
- 3
- Pages
- 600-603
- ISSN
- 0021-9738
- Cited by
- 361
- References
- 2
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Conditional gene targeting. https://app.cochat.ai/papers/10.1172/jci118828
- The paper
- Rajewsky, K., Gu, H., Kühn, R., Betz, U. A., Müller, W., Roes, J., & Schwenk, F. (1996). Conditional gene targeting. Journal of Clinical Investigation. https://doi.org/10.1172/jci118828
