The DOI matches its Crossref record; 188 of the 188 references it cites were found in a registry or an index.
Environmental exposures and mechanisms in allergy and asthma development
Open accessAbstract
Environmental exposures interplay with human host factors to promote the development and progression of allergic diseases. The worldwide prevalence of allergic disease is rising as a result of complex gene-environment interactions that shape the immune system and host response. Research shows an association between the rise of allergic diseases and increasingly modern Westernized lifestyles, which are characterized by increased urbanization, time spent indoors, and antibiotic usage. These environmental changes result in increased exposure to air and traffic pollution, fungi, infectious agents, tobacco smoke, and other early-life and lifelong risk factors for the development and exacerbation of asthma and allergic diseases. It is increasingly recognized that the timing, load, and route of allergen exposure affect allergic disease phenotypes and development. Still, our ability to prevent allergic diseases is hindered by gaps in understanding of the underlying mechanisms and interaction of environmental, viral, and allergen exposures with immune pathways that impact disease development. This Review highlights epidemiologic and mechanistic evidence linking environmental exposures to the development and exacerbation of allergic airway responses.
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Dysregulation of the epithelial barrier by environmental and other exogenous factors
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Aerts, R., Dujardin, S., Nemery, B., Van Nieuwenhuyse, A., Van Orshoven, J., Aerts, J.-M., Somers, B., Hendrickx, M., Bruffaerts, N., Bauwelinck, M., et al. (2020) · Environmental Research · doi:10.1016/j.envres.2020.109914 · Cited by 48
Helminth Therapy for Immune-Mediated Inflammatory Diseases: Current and Future Perspectives
Shi, W., Xu, N., Wang, X., Vallée, I., Liu, M., & Liu, X. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s348079 · Cited by 46
Pollen respiratory allergy: Is it really seasonal?
D'Amato, G., Murrieta-Aguttes, M., D'Amato, M., & Ansotegui, I. J. (2023) · World Allergy Organization Journal · doi:10.1016/j.waojou.2023.100799 · Cited by 36
Association between Green Space Structure and the Prevalence of Asthma: A Case Study of Toronto
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Metadata
- Authors
- Murrison, L. B., Brandt, E. B., Myers, J. B., & Hershey, G. K. K.
- Venue
- Journal of Clinical Investigation
- Published
- 2019-02-11
- Volume
- 129
- Issue
- 4
- Pages
- 1504-1515
- ISSN
- 0021-9738 (ISSN-L)
- 1558-8238
- OpenAlex
- W2914949223
- Cited by
- 391
- References
- 188
- FWCI
- 21.00
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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