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Promises, promises, and precision medicine
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“The goal of precision medicine (individually tailored treatments) is not being achieved for neurobehavioural conditions such as psychiatric disorders.”
From Precision clinical trials: a framework for getting to precision medicine for neurobehavioural disorders (2021) · cites this paper as [27]
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Le Tourneau, C., Delord, J.-P., Gonçalves, A., Gavoille, C., Dubot, C., Isambert, N., Campone, M., Trédan, O., Massiani, M.-A., Mauborgne, C., et al. (2015) · The Lancet Oncology · doi:10.1016/s1470-2045(15)00188-6 · Cited by 1,137
Medical and Ethical Consequences of the Human Genome Project
Collins, F. S. (1991) · The Journal of Clinical Ethics · doi:10.1086/jce199102411 · Cited by 663
Medical and Societal Consequences of the Human Genome Project
Collins, F. S. (1999) · New England Journal of Medicine · doi:10.1056/nejm199907013410106 · Cited by 586
Pesch, B., Kendzia, B., Gustavsson, P., Jöckel, K., Johnen, G., Pohlabeln, H., Olsson, A., Ahrens, W., Gross, I. M., Brüske, I., et al. (2012) · International Journal of Cancer · doi:10.1002/ijc.27339 · Cited by 509
Hollands, G. J., French, D., Griffin, S. J., Prevost, A. T., Sutton, S. R., King, S., & Marteau, T. M. (2016) · BMJ · doi:10.1136/bmj.i1102 · Cited by 499
Estimation of the Percentage of US Patients With Cancer Who Benefit From Genome-Driven Oncology
Marquart, J. P., Chen, E. Y.-S., & Prasad, V. K. (2018) · JAMA Oncology · doi:10.1001/jamaoncol.2018.1660 · Cited by 386
Functional precision cancer medicine—moving beyond pure genomics
Letai, A. (2017) · Nature Medicine · doi:10.1038/nm.4389 · Cited by 366
When Quality Beats Quantity: Decision Theory, Drug Discovery, and the Reproducibility Crisis
Scannell, J. W., & Bosley, J. (2016) · PLOS ONE · doi:10.1371/journal.pone.0147215 · Cited by 279
Genotype-Guided vs Clinical Dosing of Warfarin and Its Analogues
Stergiopoulos, K., & Brown, D. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2014.2368 · Cited by 125
Predicting Polygenic Obesity Using Genetic Information
Loos, R. J. F., & Janssens, A. C. J. W. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.02.013 · Cited by 120
PCSK9: From discovery to therapeutic applications
Farnier, M. (2014) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2013.10.007 · Cited by 99
SoRelle, J. A., Thodeson, D. M., Arnold, S., Gotway, G. K., & Park, J. Y. (2018) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2018.2302 · Cited by 63
Selak, V., Webster, R. J., Stepien, S., Bullen, C., Patel, A. A., Thom, S., Arroll, B., Bots, M. L., Brown, A. D. H., Crengle, S. M., et al. (2018) · Heart · doi:10.1136/heartjnl-2018-313108 · Cited by 61
Epidemiology in wonderland: Big Data and precision medicine
Saracci, R. (2018) · European Journal of Epidemiology · doi:10.1007/s10654-018-0385-9 · Cited by 54
Marginal role for 53 common genetic variants in cardiovascular disease prediction
Morris, R. W., Cooper, J. A., Shah, T., Wong, A., Drenos, F., Engmann, J., McLachlan, S., Jefferis, B. J. M. H., Dale, C. E., Hardy, R., et al. (2016) · Heart · doi:10.1136/heartjnl-2016-309298 · Cited by 32
Value of Personalized Medicine
Snyderman, R., Meade, C., & Drake, C. (2016) · JAMA · doi:10.1001/jama.2015.17136 · Cited by 23
Sharma, D., Xing, S., Hung, Y.-T., Caskey, R. N., Dowell, M. L., & Touchette, D. R. (2018) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-018-0914-3 · Cited by 20
Is Precision Medicine an Oxymoron?
Eckhardt, S. G., & Lieu, C. H. (2018) · JAMA Oncology · doi:10.1001/jamaoncol.2018.5099 · Cited by 20
Flagged first, then by citations
Research works printed but not linked: 1
- Francis S. Collins (@NIHDirector), “I am here at the #JoinAllofUs Twitter chat! Ask me questions on #PrecisionMedicine & the @AllofUsResearch Program for the next 30 minutes,” Twitter, May 8, 2018, 10:31 am, https://twitter.com/nihdirector/status/993906139036356608 Accessed December 20, 2018
Cited by
Sorted by citations
Obesity Phenotypes, Diabetes, and Cardiovascular Diseases
Piché, M., Tchernof, A., & Després, J. (2020) · Circulation Research · doi:10.1161/circresaha.120.316101 · Cited by 2,133
The ‘Digital Twin’ to enable the vision of precision cardiology
Acero, J. C., Margara, F., Marciniak, M., Rodero, C., Lončarić, F., Feng, Y., Gilbert, A., Fernandes, J. F., Bukhari, S. H. A., Wajdan, A., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa159 · Cited by 987
Rolfo, C., Mack, P., Scagliotti, G. V., Aggarwal, C., Arcila, M. E., Barlesi, F., Bivona, T., Diehn, M., Dive, C., Dziadziuszko, R., et al. (2021) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2021.06.017 · Cited by 683
Radiomics: from qualitative to quantitative imaging
Rogers, W., Seetha, S. T., Refaee, T., Lieverse, R. I. Y., Granzier, R. W. Y., Ibrahim, A., Keek, S. A., Sanduleanu, S., Primakov, S. P., Beuque, M. P. L., et al. (2020) · British Journal of Radiology · doi:10.1259/bjr.20190948 · Cited by 391
Precision Medicine: Disease Subtyping and Tailored Treatment
Wang, R. C., & Wang, Z. (2023) · Cancers · doi:10.3390/cancers15153837 · Cited by 354
Metadata
- Authors
- Joyner, M. J., & Paneth, N.
- Affiliations
- Mayo Clinic (US)
- Michigan State University (US)
- Corresponding author
- Paneth, Nigel
- Venue
- Journal of Clinical Investigation
- Published
- 2019-01-28
- Volume
- 129
- Issue
- 3
- Pages
- 946-948
- ISSN
- 0021-9738 (ISSN-L)
- 1558-8238
- PMC
- PMC6391102
- OpenAlex
- W2911598022
- Cited by
- 171
- References
- 18
- Citations by year
- 2026: 7 · 2025: 15 · 2024: 22 · 2023: 24 · 2022: 35 · 2021: 30 · 2020: 19 · 2019: 18
- FWCI
- 24.39
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Science, Research, and Medicine
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Technology and Human Factors in Education and Health
- Keywords
- precision medicine, personalized medicine
- MeSH terms
- Clinical Decision-Making, Humans, Precision Medicine
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