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Osteoclast Activation and Inflammatory Bone Diseases: Focusing on Receptors in Osteoclasts

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Eggshell Microparticle Reinforced Scaffolds for Regeneration of Critical Sized Cranial Defects

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Nano-Drug Delivery Systems for Bone Metastases: Targeting the Tumor–Bone Microenvironment

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MiR-27a-3p Targets GLP1R to Regulate Differentiation, Autophagy, and Release of Inflammatory Factors in Pre-Osteoblasts via the AMPK Signaling Pathway

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The interplay between the immune microenvironment and bone aging: From molecular mechanisms to therapeutic interventions

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Efferocytosis and Bone Dynamics

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Network Pharmacology-Based Strategy and Molecular Docking to Explore the Potential Mechanism of Jintiange Capsule for Treating Osteoporosis

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Carnitine functions as an enhancer of NRF2 to inhibit osteoclastogenesis via regulating macrophage polarization in osteoporosis

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C-type lectin Mincle initiates IL-17-mediated inflammation in acute exacerbations of idiopathic pulmonary fibrosis

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The roles of extracellular vesicles released by mechanically stimulated osteocytes in regulating osteoblast and osteoclast functions

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New Insights into the Pro-Inflammatory and Osteoclastogenic Profile of Circulating Monocytes in Osteoarthritis Patients

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A review of bacterial and osteoclast differentiation in bone infection

Dong, Q., Zhou, J., Feng, M., Kong, L., Fang, B., & Zhang, Z. (2024) · Microbial Pathogenesis · doi:10.1016/j.micpath.2024.107102 · Cited by 11

Metformin attenuates diabetic osteoporosis by suppressing ferroptosis via the AMPK/Nrf2 pathway

Liu, Y., Fu, Z., Wang, X., Yang, Q., Liu, S., & Zhu, D. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1527316 · Cited by 13

Macrophages and osteoclasts: similarity and divergence between bone phagocytes

Halper, J., Dolfi, B., Ivanov, S., Madel, M., & Blin‐Wakkach, C. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1683872 · Cited by 12

Pathogenesis, assessment, and management of bone loss in axial spondyloarthritis

Nakamura, A., & Towheed, T. (2023) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2023.152345 · Cited by 11

Advances in mechanism and management of bone homeostasis in osteonecrosis: a review article from basic to clinical applications

Xiang, X.-N., He, H., & He, C. (2024) · International Journal of Surgery · doi:10.1097/js9.0000000000002094 · Cited by 12

Periprosthetic osteolysis: Mechanisms and potential treatment strategies

Yao, F., Bao, Y., Meng, Q., Chen, Y., Zhao, L., Wang, P. Y., & Zhou, B. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.111758 · Cited by 10

Osteocyte necroptosis drives osteoclastogenesis and alveolar bone resorption during orthodontic tooth movement

Ohori, F., Kitaura, H., Marahleh, A., Ma, J., Miura, M., Ren, J., Narita, K., Fan, Z., Lin, A., & Mizoguchi, I. (2025) · Scientific Reports · doi:10.1038/s41598-025-04697-8 · Cited by 12

Microfluidic Co-culture Platforms for Studying Osteocyte Regulation of Other Cell Types under Dynamic Mechanical Stimulation

Lin, C.-Y., Song, X., Seaman, K., & You, L. (2022) · Current Osteoporosis Reports · doi:10.1007/s11914-022-00748-5 · Cited by 10

The efficiency of genetically modified mesenchymal stromal cells combined with a functionally graded scaffold for bone regeneration in corticosteroid‐induced osteonecrosis of the femoral head in rabbits

Tsubosaka, M., Maruyama, M., Lui, E., Moeinzadeh, S., Huang, E. E., Kushioka, J., Hirata, H., Jain, C. M., Storaci, H. W., Chan, C. K., et al. (2023) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37495 · Cited by 10

Dimethyloxalylglycine Attenuates Steroid-Associated Endothelial Progenitor Cell Impairment and Osteonecrosis of the Femoral Head by Regulating the HIF-1α Signaling Pathway

Shao, W., Li, Z., Wang, B., Gong, S., Wang, P., Song, B., Chen, Z.-X., & Feng, Y. (2023) · Biomedicines · doi:10.3390/biomedicines11040992 · Cited by 9

Osteoclast: The novel whistleblower in osteonecrosis of the femoral head

Qi, M., Wang, Y., Yuan, T., Su, Y., Li, Z., & Sun, S. (2023) · Gene Reports · doi:10.1016/j.genrep.2023.101833 · Cited by 10

DAMPs, PAMPs, NLRs, RIGs, CLRs and TLRs – Understanding the Alphabet Soup in the Context of Bone Biology

Carroll, K. A., Sawden, M., & Sharma, S. (2025) · Current Osteoporosis Reports · doi:10.1007/s11914-024-00900-3 · Cited by 10

The Role of Persistent Inflammation in the Pathogenesis of Infected Nonunion: A Narrative Review

Liu, T., Li, F., Yan, Y., Gao, S., Zhou, D., Jiang, X., Song, C., Fu, Z., & Liu, Z. (2025) · Immunity Inflammation and Disease · doi:10.1002/iid3.70260 · Cited by 9

miR-208a-3p discriminates osteoporosis, predicts fracture, and regulates osteoclast activation through targeting STC1

Qian, H., Jia, F., & Qin, H. (2025) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-025-05512-w · Cited by 7

New Insight into Bone Immunity in Marrow Cavity and Cancellous Bone Microenvironments and Their Regulation

Pu, H., Ding, L., Jiang, P., Li, G., Wang, W., Jiang, J., & Gan, X. (2025) · Biomedicines · doi:10.3390/biomedicines13102426 · Cited by 7

TGF-β in the Secretome of Irradiated Peripheral Blood Mononuclear Cells Supports In Vitro Osteoclastogenesis

Panahipour, L., Kargarpour, Z., Laggner, M., Mildner, M., Ankersmit, H. J., & Gruber, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228569 · Cited by 7

Development and validation of a gene signature predicting the risk of postmenopausal osteoporosis

Yuan, W., Yang, M., & Zhu, Y. (2022) · Bone and Joint Research · doi:10.1302/2046-3758.118.bjr-2021-0565.r1 · Cited by 7

LEP O-GlcNAcylation inactivates NF-κB pathway by suppressing LEP protein level and thus mediates cellular senescence and osteogenic differentiation in mouse mesenchymal stem cells

Zhang, Z., Zhou, C., & Yu, L. (2024) · BMC Molecular and Cell Biology · doi:10.1186/s12860-024-00523-7 · Cited by 6

Salidroside inhibits osteoclast differentiation based on osteoblast-osteoclast interaction via HIF-1α pathway

Jin, Y., Wang, Y., Wang, C., Zhang, L., Gao, D., Liu, H., Cao, Q., Bian, Y., Bian, Y., & Wang, Y. (2025) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(25)60864-8 · Cited by 6

Fracture-Induced Immunological Cascades Trigger Rapid Systemic Bone Loss via Osteocyte-Regulated Osteoclastogenesis

Sun, L., Kuang, S., Li, Y., Wang, G., Sun, J., Zhou, F., & Zhang, C. (2025) · ImmunoTargets and Therapy · doi:10.2147/itt.s533552 · Cited by 6

Osteocyte death promotes bone loss

McHugh, J. (2020) · Nature Reviews Rheumatology · doi:10.1038/s41584-020-0498-x · Cited by 16

Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation

Fuji, H., Ohmae, S., Noma, N., Takeiri, M., Yasutomi, H., Izumi, K., Ito, M., Toyomoto, M., Iwaki, S., Takemoto, K., et al. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.05.153 · Cited by 10

The impact of the C-type lectin receptor Mincle on osteoclast-mediated bone remodeling

Andreev, D. (2020)

Methods to Analyze the Roles of TAK1, TRAF6, and NEMO in the Regulation of NF-κB Signaling by RANK Stimulation During Osteoclastogenesis

Swarnkar, G., Arra, M., Adapala, S., & Abu‐Amer, Y. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1669-7_16 · Cited by 7

Clec4a2 deficiency promotes post-fission osteoclast cell death and suppresses acute inflammation-induced bone loss in the mouse

Fujita, H., Tai, Y., Takahashi, K., Ueda, Y., Kitagawa, W., Ono, M., Oohashi, T., & Ohuchi, H. (2026) · Bone · doi:10.1016/j.bone.2026.117797