The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
SARS–CoV-2 infection of the placenta
Open accessAbstract
BACKGROUNDThe effects of the novel coronavirus disease 2019 (COVID-19) in pregnancy remain relatively unknown. We present a case of second trimester pregnancy with symptomatic COVID-19 complicated by severe preeclampsia and placental abruption.METHODSWe analyzed the placenta for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through molecular and immunohistochemical assays and by and electron microscopy and measured the maternal antibody response in the blood to this infection.RESULTSSARS-CoV-2 localized predominantly to syncytiotrophoblast cells at the materno-fetal interface of the placenta. Histological examination of the placenta revealed a dense macrophage infiltrate, but no evidence for the vasculopathy typically associated with preeclampsia.CONCLUSIONThis case demonstrates SARS-CoV-2 invasion of the placenta, highlighting the potential for severe morbidity among pregnant women with COVID-19.FUNDINGBeatrice Kleinberg Neuwirth Fund and Fast Grant Emergent Ventures funding from the Mercatus Center at George Mason University. The funding bodies did not have roles in the design of the study or data collection, analysis, and interpretation and played no role in writing the manuscript.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Nextstrain: real-time tracking of pathogen evolution
Hadfield, J., Megill, C., Bell, S. M., Huddleston, J., Potter, B., Callender, C., Sagulenko, P., Bedford, T., & Neher, R. A. (2018) · Bioinformatics · doi:10.1093/bioinformatics/bty407 · Cited by 3,154
Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19
Zhang, Y., Xiao, M., Zhang, S., Xia, P., Cao, W., Jiang, W., Chen, H., Ding, X., Zhao, H., Zhang, H., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmc2007575 · Cited by 2,179
A serological assay to detect SARS-CoV-2 seroconversion in humans
Amanat, F., Stadlbauer, D., Strohmeier, S., Nguyen, T. H. O., Chromikova, V., McMahon, M., Jiang, K., Arunkumar, G. A., Jurczyszak, D., Polanco, J., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0913-5 · Cited by 1,769
Schwartz, D. A. (2020) · Archives of Pathology & Laboratory Medicine · doi:10.5858/arpa.2020-0901-sa · Cited by 976
Cited by
The protein expression profile of ACE2 in human tissues
Hikmet, F., Méar, L., Edvinsson, Å., Micke, P., Uhlén, M., & Lindskog, C. (2020) · Molecular Systems Biology · doi:10.15252/msb.20209610 · Cited by 1,016
Neuroinvasion of SARS-CoV-2 in human and mouse brain
Song, E., Zhang, C., Israelow, B., Lu-Culligan, A., Prado, A. V., Skriabine, S., Lu, P., Weizman, O.-E., Liu, F., Dai, Y., et al. (2020) · doi:10.1101/2020.06.25.169946 · Cited by 1,064
Self-citationAnalysis of SARS-CoV-2 vertical transmission during pregnancy
Fenizia, C., Biasin, M., Cetin, I., Vergani, P., Mileto, D., Spinillo, A., Gismondo, M. R., Perotti, F., Callegari, C., Mancon, A., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18933-4 · Cited by 361
Synthesis and systematic review of reported neonatal SARS-CoV-2 infections
Raschetti, R., Vivanti, A. J., Vauloup-Fellous, C., Loi, B., Benachi, A., & De Luca, D. (2020) · Nature Communications · doi:10.1038/s41467-020-18982-9 · Cited by 328
Adhikari, E. H., Moreno, W., Zofkie, A. C., MacDonald, L., McIntire, D. D., Collins, R. R. J., & Spong, C. Y. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.29256 · Cited by 292
Metadata
- Authors
- Hosier, H., Farhadian, S. F., Morotti, R. A., Deshmukh, U., Lu-Culligan, A., Campbell, K. H., Yasumoto, Y., Vogels, C. B. F., Casanovas-Massana, A., Vijayakumar, P., Geng, B., Odio, C. D., Fournier, J., Brito, A. F., Fauver, J. R., Liu, F., Alpert, T., Tal, R., Szigeti-Buck, K., Perincheri, S., Larsen, C., Gariepy, A. M., Aguilar, G., Fardelmann, K. L., Harigopal, M., Taylor, H. S., Pettker, C. M., Wyllie, A. L., Cruz, C. D., Ring, A. M., Grubaugh, N. D., Ko, A. I., Horvath, T. L., Iwasaki, A., Reddy, U. M., & Lipkind, H. S.
- Venue
- Journal of Clinical Investigation
- Published
- 2020-08-17
- Volume
- 130
- Issue
- 9
- Pages
- 4947-4953
- ISSN
- 0021-9738 (ISSN-L)
- 1558-8238
- OpenAlex
- W3036535913
- Cited by
- 511
- References
- 4
- FWCI
- 62.00
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: SARS–CoV-2 infection of the placenta. https://app.cochat.ai/papers/10.1172/jci139569
- The paper
- Hosier, H., Farhadian, S. F., Morotti, R. A., Deshmukh, U., Lu-Culligan, A., Campbell, K. H., Yasumoto, Y., Vogels, C. B. F., Casanovas-Massana, A., Vijayakumar, P., Geng, B., Odio, C. D., Fournier, J., Brito, A. F., Fauver, J. R., Liu, F., Alpert, T., Tal, R., Szigeti-Buck, K., . . . Lipkind, H. S. (2020). SARS–CoV-2 infection of the placenta. Journal of Clinical Investigation. https://doi.org/10.1172/jci139569
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
