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Cited by 588

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

DC-based cancer vaccines

Open access
Gilboa, Eli·2007·Journal of Clinical Investigation

Abstract

Because of the large preexisting antigenic load and immunosuppressive environment within a tumor, inducing therapeutically useful antitumor immunity in cancer patients requires the development of powerful vaccination protocols. An approach gaining increasing popularity in the tumor vaccine field is to immunize cancer patients with their own DCs loaded ex vivo with tumor antigens. The underlying premise of this approach is that the efficiency and control over the vaccination process provided by ex vivo manipulation of the DCs generates an optimally potent APC and a superior method for stimulating antitumor immunity in vivo compared with the more conventional direct vaccination methods, offsetting the added cost and complexity associated with this form of customized cell therapy.

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Metadata

Authors
Gilboa, E.
Venue
Journal of Clinical Investigation
Published
2007-05-01
Volume
117
Issue
5
Pages
1195-1203
ISSN
0021-9738 (ISSN-L)
OpenAlex
W2004911979
Cited by
588
References
5
FWCI
21.83
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: DC-based cancer vaccines. https://app.cochat.ai/papers/10.1172/jci31205
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Gilboa, E. (2007). DC-based cancer vaccines. Journal of Clinical Investigation. https://doi.org/10.1172/jci31205

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.