The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
Mechanisms of lymphatic metastasis
Open accessAbstract
Malignant tumors release growth factors such as VEGF-C to induce lymphatic vessel expansion (lymphangiogenesis) in primary tumors and in draining sentinel LNs, thereby promoting LN metastasis. Surprising recent evidence suggests that lymphatic vessels do not merely represent passive channels for tumor spread, but that they may actively promote tumor cell recruitment to LNs, cancer stem cell survival, and immune modulation. New imaging approaches allow the sensitive visualization of the earliest LN metastases and the quantitative, noninvasive measurement of the function of tumor-draining lymphatic vessels, with potential applications in the development of biomarkers for prognosis and measurement of therapeutic response.
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Cites
Involvement of chemokine receptors in breast cancer metastasis
Müller, A., Homey, B., Soto, H., Ge, N., Catron, D., Buchanan, M. E., McClanahan, T., Murphy, E., Yuan, W., Wagner, S. N., et al. (2001) · Nature · doi:10.1038/35065016 · Cited by 5,340
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Peinado, H., Alečković, M., Lavotshkin, S., Matei, I., Costa-Silva, B., Moreno-Bueno, G., Hergueta-Redondo, M., Williams, C., García-Santos, G., Ghajar, C. M., et al. (2012) · Nature Medicine · doi:10.1038/nm.2753 · Cited by 3,715
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
Skobe, M., Hawighorst, T., Jackson, D. G., Prevo, R., Janes, L., Velasco, P., Riccardi, L., Alitalo, K., Claffey, K., & Detmar, M. (2001) · Nature Medicine · doi:10.1038/84643 · Cited by 1,733
Self-citationLYVE-1, a New Homologue of the CD44 Glycoprotein, Is a Lymph-specific Receptor for Hyaluronan
Banerji, S., Ni, J., Wang, S.-X., Clasper, S., Su, J., Tammi, R., Jones, M., & Jackson, D. G. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.144.4.789 · Cited by 1,583
Prox1 Function Is Required for the Development of the Murine Lymphatic System
Wigle, J. T., & Oliver, G. (1999) · Cell · doi:10.1016/s0092-8674(00)81511-1 · Cited by 1,579
Lymphangiogenesis: Molecular Mechanisms and Future Promise
Tammela, T., & Alitalo, K. (2010) · Cell · doi:10.1016/j.cell.2010.01.045 · Cited by 1,441
Kaipainen, A., Korhonen, J., Mustonen, T., van Hinsbergh, V. W., Fang, G. H., Dumont, D., Breitman, M., & Alitalo, K. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.8.3566 · Cited by 1,423
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
Stacker, S. A., Caesar, C., Baldwin, M. E., Thornton, G. E., Williams, R. A., Prevo, R., Jackson, D. G., Nishikawa, S.-I., Kubo, H., & Achen, M. G. (2001) · Nature Medicine · doi:10.1038/84635 · Cited by 1,246
Angiosarcomas Express Mixed Endothelial Phenotypes of Blood and Lymphatic Capillaries
Breiteneder-Geleff, S., Soleiman, A., Kowalski, H., Horvat, R., Amann, G., Kriehuber, E., Diem, K., Weninger, W., Tschachler, E., Alitalo, K., et al. (1999) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)65285-6 · Cited by 1,090
Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis
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Cited by
Emerging Biological Principles of Metastasis
Lambert, A. W., Pattabiraman, D. R., & Weinberg, R. A. (2017) · Cell · doi:10.1016/j.cell.2016.11.037 · Cited by 3,067
Exosomal long noncoding RNA LNMAT2 promotes lymphatic metastasis in bladder cancer
Chen, C., Luo, Y., He, W., Zhao, Y., Kong, Y., Liu, H., Zhong, G., Li, Y., Li, J., Huang, J., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci130892 · Cited by 389
Gonzalez-Avila, G., Sommer, B., Mendoza-Posada, D. A., Ramos, C., Garcia-Hernandez, A. A., & Falfan-Valencia, R. (2019) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2019.02.010 · Cited by 373
RETRACTED ARTICLE: LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis
Liang, Y., Song, X., Li, Y., Chen, B., Zhao, W., Wang, L., Zhang, H., Liu, Y., Han, D., Zhang, N., et al. (2020) · Molecular Cancer · doi:10.1186/s12943-020-01206-5 · Cited by 373
RetractedLymphatic Vessel Network Structure and Physiology
Breslin, J. W., Yang, Y., Scallan, J. P., Sweat, R. S., Adderley, S. P., & Murfee, W. L. (2018) · Comprehensive Physiology · doi:10.1002/cphy.c180015 · Cited by 341
Metadata
- Authors
- Karaman, S., & Detmar, M.
- Venue
- Journal of Clinical Investigation
- Published
- 2014-03-03
- Volume
- 124
- Issue
- 3
- Pages
- 922-928
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2149163652
- Cited by
- 584
- References
- 91
- FWCI
- 14.51
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
