The DOI matches its Crossref record; 122 of the 122 references it cites were found in a registry or an index.
Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
Open accessAbstract
Our understanding of the role of myeloid-derived suppressor cells (MDSCs) in cancer is becoming increasingly complex. In addition to their eponymous role in suppressing immune responses, they directly support tumor growth, differentiation, and metastasis in a number of ways that are only now beginning to be appreciated. It is because of this increasingly complex role that these cells may become an important factor in the treatment of human cancer. In this Review, we discuss the most pertinent and controversial issues of MDSC biology and their role in promoting cancer progression and highlight how these cells may be used in the clinic, both as prognostic factors and as therapeutic targets.
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Bronte, V., Brandau, S., Chen, S.-H., Colombo, M. P., Frey, A. B., Greten, T. F., Mandruzzato, S., Murray, P. J., Ochoa, A., Ostrand-Rosenberg, S., et al. (2016) · Nature Communications · doi:10.1038/ncomms12150 · Cited by 2,751
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The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
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Self-citationNeutrophils in cancer: Neutral no more
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Metadata
- Authors
- Marvel, D., & Gabrilovich, D. I.
- Venue
- Journal of Clinical Investigation
- Published
- 2015-07-13
- Volume
- 125
- Issue
- 9
- Pages
- 3356-3364
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W1927075449
- Cited by
- 1,050
- References
- 122
- FWCI
- 48.09
- Type
- journal article
- Language
- en
- Open access
- bronze
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