The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice
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“Syndecans (13–16) and perlecan (14, 17, 18) have been shown to mediate the internalization of model remnant lipoproteins or TRL preparations enriched in LPL or apoE.”
From Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice (2009) · cites this paper as [17]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Thus, we believe that the genetic data presented here and previously (9), coupled with numerous cell culture studies by other groups over the years (13–19, 21), argue for independent action of proteoglycans in the hepatic”
From Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice (2009) · cites this paper as [17]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“coupled with numerous cell culture studies by other groups over the years (13–19, 21), argue for independent action of proteoglycans in the hepatic clearance of triglyceride-rich remnants.”
From Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice (2009) · cites this paper as [17]
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In the citing paper
“Interestingly, livers from insulin-deficient rodents show reduced HS production (66, 67), reduced sulfation of the chains (68), and decreased expression of Ndst1 (69,70).”
From Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members (2007) · cites this paper as [66]
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Citations
Cites
Rohlmann, A., Gotthardt, M., Hammer, R. E., & Herz, J. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1240 · Cited by 455 · cited 2×
“In otherwise normal mice, decreased LRP activity produces LDL-R upregulation and increased plasma apoB48 but no significant alterations in plasma TG and cholesterol have been reported (72).”
Background
Research works printed but not linked: 90
- Królewski, 1987, Am J Cardiol, 59, 750, 10.1016/0002-9149(87)91086-1 · DOI
- Jensen, 1987, Diabetologia, 30, 144, 10.1007/BF00274218 · DOI
- Winocour, 1989, Q J Med, 70, 265
- 1992, Diabetes Care, 15, 886, 10.2337/diacare.15.7.886 · DOI
- Rivellese, 1988, Diabetologia, 31, 884, 10.1007/BF00265371 · DOI
- Patti, 1993, Diabetologia, 36, 155, 10.1007/BF00400698 · DOI
- Perez, 1997, Diabetes Res Clin Pract, 36, 83, 10.1016/S0168-8227(97)00033-8 · DOI
- Dunn, 1992, Diabetes, 41(Suppl. 2), 102, 10.2337/diab.41.2.S102 · DOI
- Georgopoulos, 1991, J Lipid Res, 32, 1133, 10.1016/S0022-2275(20)41976-5 · DOI
- Phillips, 1993, Circulation, 88, 2762, 10.1161/01.CIR.88.6.2762 · DOI
- Groot, 1991, Arterioscler Thromb, 11, 653, 10.1161/01.ATV.11.3.653 · DOI
- Ginsberg, 1995, Arterioscler Thromb Vasc Biol, 15, 1829, 10.1161/01.ATV.15.11.1829 · DOI
- Sharrett, 1995, Arterioscler Thromb Vasc Biol, 15, 2122, 10.1161/01.ATV.15.12.2122 · DOI
- Cooper, 1997, J Lipid Res, 38, 2173, 10.1016/S0022-2275(20)34932-4 · DOI · Paper page
- Fried, 1993, J Clin Invest, 92, 2191, 10.1172/JCI116821 · DOI
- Ginsberg, 1991, Diabetes Care, 14, 839, 10.2337/diacare.14.9.839 · DOI
- Eckel, 1988, Diabetes, 37, 610, 10.2337/diab.37.5.610 · DOI
- Tsutsumi, 1995, Diabetes, 44, 414, 10.2337/diab.44.4.414 · DOI
- Shimada, 1995, Arterioscler Thromb Vasc Biol, 15, 1688, 10.1161/01.ATV.15.10.1688 · DOI
- Li, 1995, J Clin Invest, 96, 2601, 10.1172/JCI118324 · DOI · Paper page
- Brown, 1972, Biochem Biophys Res Commun, 46, 375, 10.1016/S0006-291X(72)80149-9 · DOI
- Havel, 1973, Biochemistry, 12, 1828, 10.1021/bi00733a026 · DOI
- Ebara, 1997, J Clin Invest, 99, 2672, 10.1172/JCI119456 · DOI
- Kowal, 1990, J Biol Chem, 265, 10771, 10.1016/S0021-9258(18)87014-4 · DOI · Paper page
- Windler, 1980, J Biol Chem, 255, 10464, 10.1016/S0021-9258(19)70487-6 · DOI
- Sehayek, 1991, J Biol Chem, 266, 18259, 10.1016/S0021-9258(18)55263-7 · DOI · Paper page
- Al Muhtaseb, 1992, Pediatrics, 89, 936, 10.1542/peds.89.5.936 · DOI
- Al-Muhtaseb, 1991, Diabet Med, 8, 732, 10.1111/j.1464-5491.1991.tb01692.x · DOI
- Rubinsztein, 1990, J Clin Invest, 86, 1306, 10.1172/JCI114839 · DOI · Paper page
- Hui, 1981, J Biol Chem, 256, 5646, 10.1016/S0021-9258(19)69254-9 · DOI · Paper page
- Kita, 1982, Proc Natl Acad Sci USA, 9, 3623, 10.1073/pnas.79.11.3623 · DOI · Paper page
- Herz, 1988, EMBO J, 7, 4119, 10.1002/j.1460-2075.1988.tb03306.x · DOI
- Kowal, 1989, Proc Natl Acad Sci USA, 86, 5810, 10.1073/pnas.86.15.5810 · DOI
- Misra, 1999, J Biol Chem, 274, 25785, 10.1074/jbc.274.36.25785 · DOI
- Curtin, 1996, Acta Diabetol, 33, 205, 10.1007/BF02048544 · DOI
- Karpe, 1999, Metabolism, 48, 301, 10.1016/S0026-0495(99)90076-8 · DOI
- Farese, 1996, Proc Natl Acad Sci USA, 93, 6393, 10.1073/pnas.93.13.6393 · DOI
- Véniant, 1998, J Clin Invest, 102, 1559, 10.1172/JCI4164 · DOI
- Kunjathoor, 1996, J Clin Invest, 97, 1767, 10.1172/JCI118604 · DOI
- Havel, 1955, J Clin Invest, 34, 1345, 10.1172/JCI103182 · DOI
- Shachter, 1996, J Clin Invest, 98, 846, 10.1172/JCI118857 · DOI
- de Silva, 1994, J Biol Chem, 269, 2324, 10.1016/S0021-9258(17)42171-5 · DOI
- McCormick, 1996, J Biol Chem, 271, 11963, 10.1074/jbc.271.20.11963 · DOI
- Smith, 1990, J Biol Chem, 265, 14709, 10.1016/S0021-9258(18)77166-4 · DOI
- Chen, 1994, J Lipid Res, 35, 1918, 10.1016/S0022-2275(20)39938-7 · DOI
- Aalto-Setälä, 1992, J Clin Invest, 90, 1889, 10.1172/JCI116066 · DOI
- Jong, 1996, Arterioscler Thromb Vasc Biol, 16, 934, 10.1161/01.ATV.16.8.934 · DOI
- Baginsky, 1977, J Lipid Res, 18, 423, 10.1016/S0022-2275(20)41659-1 · DOI
- Paigen, 1985, Atherosclerosis, 57, 65, 10.1016/0021-9150(85)90138-8 · DOI
- Bilheimer, 1972, Biochim Biophys Acta, 26, 212, 10.1016/0005-2760(72)90034-3 · DOI
- Ramakrishnan, 1990, J Lipid Res, 31, 1031, 10.1016/S0022-2275(20)42743-9 · DOI
- Wu, 1997, J Biol Chem, 272, 20627, 10.1074/jbc.272.33.20627 · DOI
- Paka, 1999, J Biol Chem, 274, 4816, 10.1074/jbc.274.8.4816 · DOI
- Pillarisetti, 1992, J Biol Chem, 267, 16517, 10.1016/S0021-9258(18)42033-9 · DOI
- Obunike, 1996, J Lipid Res, 37, 2439, 10.1016/S0022-2275(20)37492-7 · DOI
- Obunike, 2000, Arterioscler Thromb Vasc Biol, 20, 111, 10.1161/01.ATV.20.1.111 · DOI
- Wagner, 1981, Arteriosclerosis, 1, 192, 10.1161/01.ATV.1.3.192 · DOI
- Choi, 1993, J Biol Chem, 268, 15804, 10.1016/S0021-9258(18)82326-2 · DOI
- Roskams, 1995, Hepatology, 21, 950, 10.1002/hep.1840210410 · DOI
- Kako, 1999, J Lipid Res, 40, 2185, 10.1016/S0022-2275(20)32093-9 · DOI
- Bar-on, 1981, Diabetes, 30, 496, 10.2337/diab.30.6.496 · DOI
- Laakso, 1987, Diabetologia, 30, 703, 10.1007/BF00296992 · DOI
- Hansen, 1997, J Diabetes Complications, 11, 230, 10.1016/S1056-8727(96)00048-7 · DOI
- Donner, 1998, J Lipid Res, 39, 1805, 10.1016/S0022-2275(20)32168-4 · DOI
- Hegele, 1998, Arterioscler Thromb Vasc Biol, 18, 1212, 10.1161/01.ATV.18.8.1212 · DOI
- Boisfer, 1999, J Biol Chem, 274, 11564, 10.1074/jbc.274.17.11564 · DOI
- Weisgraber, 1990, J Biol Chem, 265, 22453, 10.1016/S0021-9258(18)45726-2 · DOI
- Jong, 1996, J Clin Invest, 98, 2259, 10.1172/JCI119036 · DOI
- Mahley, 1999, J Lipid Res, 40, 1, 10.1016/S0022-2275(20)33334-4 · DOI · Paper page
- Ji, 1995, J Lipid Res, 36, 583, 10.1016/S0022-2275(20)39892-8 · DOI
- Willnow, 1994, Science, 264, 1471, 10.1126/science.7515194 · DOI
- Ishibashi, 1994, Proc Natl Acad Sci USA, 91, 4431, 10.1073/pnas.91.10.4431 · DOI · Paper page
- Ji, 1993, J Biol Chem, 268, 10160, 10.1016/S0021-9258(18)82186-X · DOI · Paper page
- Al-Haideri, 1997, Biochemistry, 36, 12766, 10.1021/bi9631024 · DOI
- Kjellen, 1983, Diabetes, 32, 337, 10.2337/diab.32.4.337 · DOI · Paper page
- Spiro, 1987, Diabetologia, 30, 259, 10.1007/BF00270425 · DOI
- Unger, 1991, J Biol Chem, 266, 8671, 10.1016/S0021-9258(18)31496-0 · DOI · Paper page
- Kofoed-Enevoldsen, 1993, Diabetologia, 36, 310, 10.1007/BF00400233 · DOI
- Park, 1998, Nat Med, 4, 1025, 10.1038/2012 · DOI
- Rescan, 1993, Am J Pathol, 142, 199
- van der Woude, 1997, Exp Nephrol, 5, 180
- Bollineni, 1997, Curr Eye Res, 16, 127, 10.1076/ceyr.16.2.127.5089 · DOI
- Yokoyama, 1997, Diabetes, 46, 1875, 10.2337/diab.46.11.1875 · DOI
- Kanwar, 1996, J Clin Invest, 98, 2478, 10.1172/JCI119066 · DOI
- Templeton, 1996, Metabolism, 45, 1136, 10.1016/S0026-0495(96)90014-1 · DOI
- Jensen, 1997, Diabetes, 46(Suppl. 2), S98, 10.2337/diab.46.2.S98 · DOI
- Kjellen, 1983, Diabetes, 32, 337, 10.2337/diab.32.4.337 · DOI · Paper page
- Spiro, 1987, Diabetologia, 30, 259, 10.1007/BF00270425 · DOI
- Unger, 1991, J Biol Chem, 266, 8671, 10.1016/S0021-9258(18)31496-0 · DOI · Paper page
- Curtin, 1996, Acta Diabetol, 33, 205, 10.1007/BF02048544 · DOI
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Metadata
- Authors
- Ebara, T., Conde, K., Kako, Y., Liu, Y., Xu, Y., Ramakrishnan, R., Goldberg, I. J., & Shachter, N. S.
- Venue
- Journal of Clinical Investigation
- Published
- 2000-06-15
- Volume
- 105
- Issue
- 12
- Pages
- 1807-1818
- ISSN
- 0021-9738
- Cited by
- 86
- References
- 1
- Language
- en
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