Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

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26. The Role of the Melanocortin System in Binge-Like Ethanol Consumption
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35. Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort
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36. Melanocortin receptors in GtoPdb v.2021.3
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39. Endocrine Disease
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40. Senior Author Correspondence Information
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42. Obesity
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43. Endocrine Pharmacology
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44. Genetics of Obesity
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45. Genetic Factors
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57. Nutrient-gene interactions contributing to the development of obesity
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58. Genetics of the Human Obesities
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60. Bibliographie
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80. Conséquences fonctionnelles de mutations affectant le récepteur de la vasopressine de type 2 et implications thérapeutiques
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87. Nouvelle technique de détection simultanée des variant ponctuels et des copy number variants dans l’obésité monogénique
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96. BindingDB Entry 50037102: Structure-activity relationships of the melanocortin tetrapeptide Ac-His-D-Phe-Arg-Trp-NH2 at the mouse melanocortin receptors. 4. Modifications at the Trp position.
    BindingDB · 2012 · UC San Diego
97. BindingDB Entry 50037655: Mapping the binding site of melanocortin 4 receptor agonists: a hydrophobic pocket formed by I3.28(125), I3.32(129), and I7.42(291) is critical for receptor activation.
    BindingDB · 2012 · UC San Diego
98. BindingDB Entry 50037040: Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors: part 2 modifications at the Phe position.
    BindingDB · 2012 · UC San Diego
99. BindingDB Entry 50037035: Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors. 1. Modifications at the His position.
    BindingDB · 2012 · UC San Diego
100. BindingDB Entry 50007962: Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists.
     BindingDB · 2021 · UC San Diego