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The role of non-resolving inflammation in atherosclerosis
Open accessAbstract
Non-resolving inflammation drives the development of clinically dangerous atherosclerotic lesions by promoting sustained plaque inflammation, large necrotic cores, thin fibrous caps, and thrombosis. Resolution of inflammation is not merely a passive return to homeostasis, but rather an active process mediated by specific molecules, including fatty acid-derived specialized pro-resolving mediators (SPMs). In advanced atherosclerosis, there is an imbalance between levels of SPMs and proinflammatory lipid mediators, which results in sustained leukocyte influx into lesions, inflammatory macrophage polarization, and impaired efferocytosis. In animal models of advanced atherosclerosis, restoration of SPMs limits plaque progression by suppressing inflammation, enhancing efferocytosis, and promoting an increase in collagen cap thickness. This Review discusses the roles of non-resolving inflammation in atherosclerosis and highlights the unique therapeutic potential of SPMs in blocking the progression of clinically dangerous plaques.
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“Both SPMs and IL-10 promote efferocytosis36,93,181–185”
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Chistiakov, D. A., Bobryshev, Y. V., Nikiforov, N. G., Elizova, N. V., Sobenin, I. A., & Orekhov, A. N. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.03.055 · Cited by 184
RetractedAntiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
Ridker, P. M., Everett, B. M., Thuren, T., MacFadyen, J. G., Chang, W. H., Ballantyne, C., Fonseca, F., Nicolau, J., Koenig, W., Anker, S. D., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1707914 · Cited by 9,482
Lusis, A. J. (2000) · Nature · doi:10.1038/35025203 · Cited by 4,880
Cytokine-mediated regulation of CXCR4 expression in human neutrophils
Nagase, H., Miyamasu, M., Yamaguchi, M., Imanishi, M., Tsuno, N. H., Matsushima, K., Yamamoto, K., Morita, Y., & Hirai, K. (2002) · Journal of Leukocyte Biology · doi:10.1189/jlb.71.4.711 · Cited by 4,713
The M1 and M2 paradigm of macrophage activation: Time for reassessment
Martinez, F. O., & Gordon, S. (2014) · F1000Prime Reports · doi:10.12703/p6-13 · Cited by 4,689
Alternative Activation of Macrophages: An Immunologic Functional Perspective
Martinez, F. O., Helming, L., & Gordon, S. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132532 · Cited by 2,745
Macrophages in the Pathogenesis of Atherosclerosis
Moore, K. J., & Tabas, I. (2011) · Cell · doi:10.1016/j.cell.2011.04.005 · Cited by 2,669
Self-citationMechanisms of plaque formation and rupture
Bentzon, J. F., Otsuka, F., Virmani, R., & Falk, E. (2014) · Circulation Research · doi:10.1161/circresaha.114.302721 · Cited by 2,391
The immune system in atherosclerosis
Hansson, G. K., & Hermansson, A. (2011) · Nature Immunology · doi:10.1038/ni.2001 · Cited by 2,389
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Bäck, M., Yurdagul, A., Tabas, I., Öörni, K., & Kovanen, P. T. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0169-2 · Cited by 1,341
Self-citationEfferocytosis in health and disease
Doran, A. C., Yurdagul, A., & Tabas, I. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-019-0240-6 · Cited by 1,066
Self-citationThe CD47-SIRPα Immune Checkpoint
Logtenberg, M. E. W., Scheeren, F. A., & Schumacher, T. N. (2020) · Immunity · doi:10.1016/j.immuni.2020.04.011 · Cited by 760
Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Chen, W., Schilperoort, M., Cao, Y., Shi, J., Tabas, I. A., & Tao, W. (2021) · Nature Reviews Cardiology · doi:10.1038/s41569-021-00629-x · Cited by 544
Self-citationHypoxia signaling in human health and diseases: implications and prospects for therapeutics
Luo, Z., Tian, M., Yang, G., Tan, Q., Chen, Y., Li, G., Zhang, Q., Li, Y., Wan, P., & Wu, J. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01080-1 · Cited by 499
Soppert, J., Lehrke, M., Marx, N., Jankowski, J., & Noels, H. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.07.019 · Cited by 440
Lechner, K., von Schacky, C., McKenzie, A. L., Worm, N., Nixdorff, U., Lechner, B., Kränkel, N., Halle, M., Krauss, R. M., & Scherr, J. (2019) · European Journal of Preventive Cardiology · doi:10.1177/2047487319869400 · Cited by 390
The integration of inflammaging in age-related diseases
Fülöp, T., Witkowski, J. M., Olivieri, F., & Larbi, A. (2018) · Seminars in Immunology · doi:10.1016/j.smim.2018.09.003 · Cited by 368
Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis
Tabas, I. A., & Bornfeldt, K. (2020) · Circulation Research · doi:10.1161/circresaha.119.315939 · Cited by 253
Self-citationTargeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products
Wang, D., Yang, Y., Lei, Y., Tzvetkov, N. T., Liu, X., Yeung, A. W. K., Xu, S., & Atanasov, A. G. (2019) · Pharmacological Reviews · doi:10.1124/pr.118.017178 · Cited by 223
Oxidation of polyunsaturated fatty acids to produce lipid mediators
Christie, W. W., & Harwood, J. L. (2020) · Essays in Biochemistry · doi:10.1042/ebc20190082 · Cited by 231
Karunakaran, D., Nguyen, M.-A., Geoffrion, M., Vreeken, D., Lister, Z., Cheng, H. S., Otte, N., Essebier, P., Wyatt, H., Kandiah, J. W., et al. (2020) · Circulation · doi:10.1161/circulationaha.118.038379 · Cited by 220
Ye, Z.-M., Yang, S., Xia, Y., Hu, R., Chen, S., Li, B., Chen, S.-L., Luo, X., Mao, L., Li, Y., et al. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-1409-4 · Cited by 209
Bai, R., Yao, C., Zhong, Z., Ge, J., Bai, Z., Ye, X., Xie, T., & Xie, Y. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.113165 · Cited by 197
He, Z., Chen, W., Hu, K., Luo, Y., Zeng, W., He, X., Li, T., Ouyang, J., Li, Y., Xie, L., et al. (2024) · Nature Nanotechnology · doi:10.1038/s41565-024-01687-1 · Cited by 191
Targeting Mechanosensitive Transcription Factors in Atherosclerosis
Niu, N., Xu, S., Xu, Y., Little, P. J., & Jin, Z. (2019) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2019.02.004 · Cited by 194
The role of efferocytosis‐fueled macrophage metabolism in the resolution of inflammation
Schilperoort, M., Ngai, D., Sukka, S. R., Avrampou, K., Shi, H., & Tabas, I. A. (2023) · Immunological Reviews · doi:10.1111/imr.13214 · Cited by 184
Self-citationMouse Models for Atherosclerosis Research—Which Is My Line?
Oppi, S., Lüscher, T. F., & Stein, S. (2019) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2019.00046 · Cited by 195
Rutaecarpine: A promising cardiovascular protective alkaloid from Evodia rutaecarpa (Wu Zhu Yu)
Tian, K., Li, J., & Xu, S. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2018.12.019 · Cited by 178
Inflammation Resolution: Implications for Atherosclerosis
Doran, A. C. (2022) · Circulation Research · doi:10.1161/circresaha.121.319822 · Cited by 181
Self-citationNanoparticle Therapy for Vascular Diseases
Flores, A. M., Ye, J., Jarr, K.-U., Hosseini-Nassab, N., Smith, B. R., & Leeper, N. J. (2019) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.118.311569 · Cited by 155
Lechner, K., McKenzie, A. L., Kränkel, N., von Schacky, C., Worm, N., Nixdorff, U., Lechner, B., Scherr, J., Weingärtner, O., & Krauss, R. M. (2020) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2019.0115 · Cited by 148
Crosstalk Between Macrophages and Vascular Smooth Muscle Cells in Atherosclerotic Plaque Stability
Yurdagul, A. (2022) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.121.316233 · Cited by 138
Evidence for the Benefits of Melatonin in Cardiovascular Disease
Tobeiha, M., Jafari, A., Fadaei, S., Mirazimi, S. M. A., Dashti, F., Amiri, A., Khan, H. Z., Asemi, Z., Reiter, R. J., Hamblin, M. R., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.888319 · Cited by 126
Hu, Z., Guan, Y., Hu, W., Xu, Z., & Ishfaq, M. (2022) · PubMed Central · doi:10.22038/ijbms.2022.60380.13381 · Cited by 121
Inflammation, infection and atherosclerosis
Shah, P. K. (2019) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2019.01.004 · Cited by 111
Omega‐3 fatty acids, cardiovascular risk, and the resolution of inflammation
Bäck, M., & Hansson, G. K. (2019) · The FASEB Journal · doi:10.1096/fj.201802445r · Cited by 112
First we eat, then we do everything else: The dynamic metabolic regulation of efferocytosis
Trzeciak, A. J., Wang, Y., & Perry, J. S. A. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.08.001 · Cited by 109
Dong, G., Yu, J., Shan, G., Su, L., Yu, N., & Yang, S.-S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.731810 · Cited by 107
He, H., Han, Q., Wang, S., Long, M., Zhang, M., Li, Y., Zhang, Y., & Gu, N. (2023) · ACS Nano · doi:10.1021/acsnano.3c01420 · Cited by 107
Dabravolski, S. A., Sukhorukov, V. N., Kalmykov, V. A., Grechko, A. V., Shakhpazyan, N. K., & Orekhov, A. N. (2022) · Biomedicines · doi:10.3390/biomedicines10020254 · Cited by 96
Zhao, H., Liu, M., Liu, H., Suo, R., & Lu, C. (2020) · Bioscience Reports · doi:10.1042/bsr20193431 · Cited by 94
RetractedLiu, T., Xiang, A., Peng, T., Doran, A. C., Tracey, K. J., Barnes, B. J., Tabas, I. A., Son, M., & Diamond, B. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1907490116 · Cited by 93
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Arnold, N., Lechner, K., Waldeyer, C., Shapiro, M. D., & Köenig, W. (2021) · European Cardiology Review · doi:10.15420/ecr.2020.50 · Cited by 93
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Porsch, F., Mallat, Z., & Binder, C. J. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab285 · Cited by 88
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Arnardottir, H., Thul, S., Pawelzik, S., Karadimou, G., Artiach, G., Gallina, A. L., Mysdotter, V., Carracedo, M., Tarnawski, L., Caravaca, A. S., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci142883 · Cited by 87
Zheng, Q., Zou, Y., Teng, P., Chen, Z., Wu, Y., Dai, X., Li, X., Hu, Z., Wu, S., Xu, Y., et al. (2022) · Cells · doi:10.3390/cells11142191 · Cited by 84
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Conte, M. S., Desai, T. A., Wu, B., Schaller, M. S., & Werlin, E. C. (2018) · Journal of Clinical Investigation · doi:10.1172/jci97947 · Cited by 82
Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis
Geng, S., Zhang, Y., Lee, C., & Li, L. (2019) · Science Advances · doi:10.1126/sciadv.aav2309 · Cited by 80
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Stylianou, E. (2018) · Journal of Inflammation Research · doi:10.2147/jir.s129027 · Cited by 79
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Cai, D., Gao, W., Li, Z., Zhang, Y., Xiao, L., & Xiao, Y. (2022) · Biomedicines · doi:10.3390/biomedicines10051203 · Cited by 74
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Sherratt, S. C. R., Mason, R. P., Libby, P., Steg, P. G., & Bhatt, D. L. (2023) · Cardiovascular Research · doi:10.1093/cvr/cvad188 · Cited by 76
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Tanaka, M., Saka-Tanaka, M., Ochi, K., Fujieda, K., Sugiura, Y., Miyamoto, T., Kohda, H., Ito, A., Miyazawa, T., Matsumoto, A., et al. (2020) · The Journal of Experimental Medicine · doi:10.1084/jem.20192230 · Cited by 62
Xia, M., Yang, X., & Qian, C. (2020) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2020.10.043 · Cited by 62
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Gouda, N. A., Alshammari, S. O., Abourehab, M. A. S., Alshammari, Q. A., & Elkamhawy, A. (2023) · Inflammopharmacology · doi:10.1007/s10787-023-01366-y · Cited by 59
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Altamura, S., Pietropaoli, D., Lombardi, F., Pinto, R. D., & Ferri, C. (2023) · Biomedicines · doi:10.3390/biomedicines11113033 · Cited by 64
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Shah, P. K., & Lecis, D. (2019) · F1000Research · doi:10.12688/f1000research.18901.1 · Cited by 58
Opoku, E., Traughber, C. A., Zhang, D. K. Y., Iacano, A. J., Khan, M. R., Han, J., Smith, J. D., & Gulshan, K. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.715211 · Cited by 55
Liu, F., Shan, S., Li, H., Shi, J., Hao, R., Yang, R., & Li, Z. (2021) · Food & Function · doi:10.1039/d1fo00991e · Cited by 53
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Kasikara, C., Schilperoort, M., Gerlach, B. D., Xue, C., Wang, X., Zheng, Z., Kuriakose, G., Dorweiler, B., Zhang, H., Fredman, G., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci145275 · Cited by 52
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Fan, Y., Liu, J., Miao, J., Zhang, X., Yan, Y., Bai, L., Chang, J., Wang, Y., Wang, L., Bian, Y., et al. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114106 · Cited by 50
Fan, L., Liu, J., Hu, W., Chen, Z., Lan, J., Zhang, T., Zhang, Y., Wu, X., Zhong, Z., Zhang, D., et al. (2024) · Cell Research · doi:10.1038/s41422-024-00945-0 · Cited by 47
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Cimmino, G., Muscoli, S., Rosa, S. D., Cesaro, A., Perrone, M. A., Selvaggio, S., Selvaggio, G., Aimo, A., Pedrinelli, R., Mercuro, G., et al. (2023) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000001450 · Cited by 45
Yang, B., Hang, S., Xu, S., Gao, Y., Yu, W., Zang, G., Zhang, L., & Wang, Z. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e32073 · Cited by 46
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Dinakis, E., O’Donnell, J. A., & Marques, F. Z. (2024) · Acta Physiologica · doi:10.1111/apha.14193 · Cited by 49
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Hua, Y., Zhang, J., Liu, Q., Su, J., Zhao, Y., Zheng, G., Yang, Z., Zhuo, D., Ma, C., & Fan, G. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.831847 · Cited by 45
Zhang, L., Lu, L., Zhong, X., Yue, Y., Hong, Y., Li, Y., & Li, Y. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.03.006 · Cited by 44
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Wei, C., Jiang, Z., Li, C., Li, P., & Fu, Q. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202214655 · Cited by 43
Zhang, H., Gong, X., Ni, S., Wang, Y., Zhu, L., & Ji, N. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.105934 · Cited by 43
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Schaller, M. S., Chen, M., Colas, R. A., Sorrentino, T. A., Lazar, A., Grenon, S. M., Dalli, J., & Conte, M. S. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.016113 · Cited by 46
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Guo, L., Miao, Y., Wang, Y., Zhang, Y., Zhou, E.-F., Wang, J., Zhao, Y., Li, L., Wang, A., Gan, Y., et al. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202204822 · Cited by 43
Jin, F., Li, J., Guo, J., Doeppner, T. R., Hermann, D. M., Yao, G., & Dai, Y. (2021) · European Heart Journal Open · doi:10.1093/ehjopen/oeab022 · Cited by 41
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Laera, N., Malerba, P., Vacanti, G., Nardin, S., Pagnesi, M., & Nardin, M. (2023) · Life · doi:10.3390/life13112128 · Cited by 34
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Schindler, L., Zwissler, L., Krammer, C., Hendgen-Cotta, U. B., Rassaf, T., Hampton, M. B., Dickerhof, N., & Bernhagen, J. (2021) · Journal of Leukocyte Biology · doi:10.1002/jlb.3a0420-242rrr · Cited by 34
Hu, X., Li, Y., Chen, Q., Wang, T., Ma, L., Zhang, W., Yu, R., Zhang, J., Wan, J., Yu, C., et al. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110410 · Cited by 34
Lobos, C. A., González, L., Bulnes, J. F., Figuls, M. R. I., Venturelli, P. M., & Rodríguez, G. M. (2023) · Clinical Research in Cardiology · doi:10.1007/s00392-023-02291-4 · Cited by 33
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Alsina‐Sanchís, E., Mülfarth, R. I., Moll, I., Mogler, C., Rodríguez‐Vita, J., & Fischer, A. (2020) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-20-0650 · Cited by 32
Huang, C., Huang, W., Zhang, L., Zhang, C., Zhou, C., Wei, W., Li, Y., Zhou, Q., Chen, W., & Tang, Y. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14051083 · Cited by 32
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Metadata
- Authors
- Kasikara, C., Doran, A. C., Cai, B., & Tabas, I.
- Affiliations
- Columbia University (US)
- Venue
- Journal of Clinical Investigation
- Published
- 2018-07-02
- Volume
- 128
- Issue
- 7
- Pages
- 2713-2723
- ISSN
- 0021-9738 (ISSN-L)
- 1558-8238
- PMC
- PMC6025992
- OpenAlex
- W2809703637
- Cited by
- 266
- References
- 135
- Citations by year
- 2026: 14 · 2025: 27 · 2024: 28 · 2023: 37 · 2022: 43 · 2021: 46 · 2020: 39 · 2019: 25 · 2018: 7
- FWCI
- 2.96
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association (17FTF33660643, 15POST25620024)
- National Institutes of Health
- National Heart, Lung, and Blood Institute (R01HL132412, R01HL127464, P01HL087123, R01HL075662, T32HL120826)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Atherosclerosis and Cardiovascular Diseases
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Keywords
- nonresolving inflammation, atherosclerosis, specialized pro-resolving mediators, inflammation resolution, atherosclerotic plaque, necrotic core, fibrous cap, thrombosis, macrophage polarization, efferocytosis, leukocyte influx, lipid mediators, plaque progression
- MeSH terms
- Animals, Humans, Inflammation, Models, Cardiovascular, Signal Transduction, Disease Progression, Inflammation Mediators, Atherosclerosis, Lipid Metabolism, Plaque, Atherosclerotic, Lipoxygenases
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