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Family History Studies: V. The Genetics of Mania
Abstract
In this study of the families of 59 manic-depressive, manic type probands, the predominant affective illness among the family members was depression without mania, although mania was frequent. The findings suggest that genetic transmission occurred by a sex-linked single or double dominant gene. In two families affective disorder was linked to color blindness, implying that the X-linked gene for manic-depressive psychosis is on the short arm of the X chromosome.
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Citations
Cited by
Diagnostic Interview for Genetic Studies: Rationale, Unique Features, and Training
Nurnberger, J. I. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950110009002 · Cited by 2,053
Genetic linkage between X-chromosome markers and bipolar affective illness
Baron, M., Risch, N., Hamburger, R., Mandel, B., Kushner, S., Newman, M., Drumer, D., & Belmaker, R. H. (1987) · Nature · doi:10.1038/326289a0 · Cited by 416
Akiskal, H. S., & McKinney, W. T. (1973) · Science · doi:10.1126/science.182.4107.20 · Cited by 389
A family study of bipolar I disorder in adolescence
Strober, M., Morrell, W., Burroughs, J., Lampert, C., Danforth, H., & Freeman, R. (1988) · Journal of Affective Disorders · doi:10.1016/0165-0327(88)90023-7 · Cited by 345
Alcoholism: III. Diagnosis and Familial Psychiatric Illness in 259 Alcoholic Probands
Winokur, G. (1970) · Archives of General Psychiatry · doi:10.1001/archpsyc.1970.01750020008002 · Cited by 309
Self-citation
Metadata
- Authors
- REICH, T., CLAYTON, P. J., & WINOKUR, G.
- Venue
- American Journal of Psychiatry
- Published
- 1969-04
- Volume
- 125
- Issue
- 10
- Pages
- 1358-1369
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2048744836
- Cited by
- 209
- References
- 0
- FWCI
- 13.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- REICH, T., CLAYTON, P. J., & WINOKUR, G. (1969). Family History Studies: V. The Genetics of Mania. American Journal of Psychiatry. https://doi.org/10.1176/ajp.125.10.1358
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
