The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Treatment of Depression by Drugs and Psychotherapy
Abstract
Prevention of relapse following depression is a pressing research problem. The authors tested the efficacy of the tricyclic antidepressant amitriptyline and psychotherapy, alone and in combination, in preventing the relapse of 150 neurotic depressed female patients. They found that patients receiving amitriptyline and little psychotherapy had a 12-percent relapse rate, compared to a 16-percent rate for those receiving more psychotherapy and no medication. There was no significant difference between drug therapy alone or drug therapy in combination with psychotherapy. However, psychotherapy was beneficial to patients with problems of social adjustment and interpersonal relations. The need for further research and implications for treatment are discussed.
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Cites
Diagnostic and Statistical Manual of Mental Disorders
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Research works printed but not linked: 19
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- 10.1037/14489-000 · DOI
- Klerman GL, Paykel ES. Prusoff BA: Antidepressant drugs and clinical psychopathology, in Psychopathology and Psychopharmacology. Edited by Cole J, Freedman A, Friedhoff A. Baltimore.Johns Hopkins University Press, 1973, pp177-189
Cited by
Cognitive Therapy of Depression
HOLLON, S. D., & BECK, A. T. (1979) · Cognitive-Behavioral Interventions · doi:10.1016/b978-0-12-404480-7.50012-5 · Cited by 4,685
Comparative Studies of Psychotherapies: Is It True That "Everyone Has Won and All Must Have Prizes"?
Luborsky, L. (1975) · Archives of General Psychiatry · doi:10.1001/archpsyc.1975.01760260059004 · Cited by 1,485
Relapse prevention with antidepressant drug treatment in depressive disorders: a systematic review
Geddes, J. R., Carney, S. M., Davies, C., Furukawa, T. A., Kupfer, D. J., Frank, E., & Goodwin, G. M. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12599-8 · Cited by 945
Rush, A. J., Beck, A. T., Kovacs, M., & Hollon, S. (1977) · Cognitive Therapy and Research · doi:10.1007/bf01173502 · Cited by 913
Placebo interventions for all clinical conditions
Hróbjartsson, A., & Gøtzsche, P. C. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003974.pub3 · Cited by 777
Metadata
- Authors
- KLERMAN, G. L., DIMASCIO, A., WEISSMAN, M., PRUSOFF, B., & PAYKEL, E. S.
- Venue
- American Journal of Psychiatry
- Published
- 1974-02
- Volume
- 131
- Issue
- 2
- Pages
- 186-191
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2107061451
- Cited by
- 500
- References
- 2
- FWCI
- 14.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Treatment of Depression by Drugs and Psychotherapy. https://app.cochat.ai/papers/10.1176/ajp.131.2.186
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- KLERMAN, G. L., DIMASCIO, A., WEISSMAN, M., PRUSOFF, B., & PAYKEL, E. S. (1974). Treatment of Depression by Drugs and Psychotherapy. American Journal of Psychiatry. https://doi.org/10.1176/ajp.131.2.186
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
