Comparative efficacy of cognitive therapy and pharmacotherapy in the treatment of depressed outpatients
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Early improvements associated with medication changes do not explain the attrition in this trial.
“Although attrition in psychiatric treatment has been linked to early improvements associated with medication changes [50], this explanation does not seem to apply in the current trial”
From Online Mindfulness-Based Cognitive Behavioral Therapy Intervention for Youth With Major Depressive Disorders: Randomized Controlled Trial. (2021) · cites this paper as [50]
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“The early finding that cognitive therapy for depression was effective, and moreover, more effective than an antidepressant medication (Rush, Beck, Kovacs, & Hollon, 1977), reinforced the signal that the BMM was not enough, at least not for modeling and treating depression.”
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“…in the general population ~DeRubeis & Crits-Christoph, 1998!. Cognitive therapy is at least as efficacious as antidepressants in the treatment of major depression ~Rush et al., 1977; Murphy et al., 1984; Hollon et al., 1992!, even for moderate to severe major depression ~DeRubeis et al., 2005!.”
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- Authors
- Rush, A. J., Beck, A. T., Kovacs, M., & Hollon, S.
- Affiliations
- University of Oklahoma (US)
- University of Pennsylvania (US)
- Venue
- Cognitive Therapy and Research
- Published
- 1977-03
- Volume
- 1
- Issue
- 1
- Pages
- 17-37
- ISSN
- 0147-5916 (ISSN-L)
- 1573-2819
- OpenAlex
- W2092686956
- Cited by
- 913
- References
- 24
- Citations by year
- 2026: 3 · 2025: 14 · 2024: 6 · 2023: 8 · 2022: 11 · 2021: 12 · 2020: 21 · 2019: 8 · 2018: 7 · 2017: 46 · 2016: 15 · 2015: 19 · 2014: 9 · 2013: 18 · 2012: 15
- FWCI
- 60.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cognitive Therapy and Research (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- cognitive therapy, imipramine, depression, outpatients, major depressive disorder, chronic depression, treatment efficacy, remission, treatment discontinuation, relapse, anxiety, maintenance of treatment gains, antidepressant treatment
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