The DOI matches its Crossref record.
The effect of high doses of vitamin B6 on autistic children: a double- blind crossover study
Abstract
The authors used data from an earlier nonblind study to identify 16 autistic-type child outpatients who had apparently improved when given vitamin B6 (pyridoxine). In a double-blind study each child's B6 supplement was replaced during two separate experimental trial periods with either a B6 supplement or a matched placebo. Behavior was rated as deteriorating significantly during the B6 withdrawal.
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Citations
Cited by
Sensory Neuropathy from Pyridoxine Abuse: A New Megavitamin Syndrome
Schaumburg, H., Kaplan, J., Windebank, A., Vick, N., Rasmus, S., Pleasure, D., & Brown, M. J. (1983) · New England Journal of Medicine · doi:10.1056/nejm198308253090801 · Cited by 708
Chauhan, A., & Chauhan, V. (2006) · Pathophysiology · doi:10.1016/j.pathophys.2006.05.007 · Cited by 656
Dietary Interventions for Autism Spectrum Disorder: A Meta-analysis
Fraguas, D., Díaz-Caneja, C. M., Pina-Camacho, L., Moreno, C., Durán-Cutilla, M., Ayora, M., González-Vioque, E., de Matteis, M., Hendren, R. L., Arango, C., et al. (2019) · PEDIATRICS · doi:10.1542/peds.2018-3218 · Cited by 80
Metadata
- Venue
- American Journal of Psychiatry
- Published
- 1978-04-01
- Volume
- 135
- Issue
- 4
- Pages
- 472-475
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2418304392
- Cited by
- 159
- References
- 0
- FWCI
- 1.12
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The effect of high doses of vitamin B6 on autistic children: a double- blind crossover study. https://app.cochat.ai/papers/10.1176/ajp.135.4.472
- The paper
- The effect of high doses of vitamin B6 on autistic children: a double- blind crossover study. (1978). American Journal of Psychiatry. https://doi.org/10.1176/ajp.135.4.472
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
