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Cited by 259

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

From metapsychology to molecular biology: explorations into the nature of anxiety

·1983·American Journal of Psychiatry

Abstract

Through the use of animal models, specific forms of mentation can now be explored on the cellular and molecular levels. Chronic anxiety and anticipatory anxiety in humans are closely paralleled by two forms of learned fear in the sea snail Aplysia: sensitization and aversive classical conditioning. In Aplysia's simple nervous system it is possible to delineate how the two forms are acquired and maintained. Both rely on the mechanisms of presynaptic facilitation. An augmented form of presynaptic facilitation accounts for the associative component of conditioning. These findings suggest that a surprisingly simple set of cellular and molecular mechanisms in various combinations may underlie a wide range of both adaptive and maladaptive behavioral modifications.

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Crossref · 10.1176/ajp.140.10.1277

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Metadata

Venue
American Journal of Psychiatry
Published
1983-10-01
Volume
140
Issue
10
Pages
1277-1293
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
OpenAlex
W144537577
Cited by
259
References
11
FWCI
9.85
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: From metapsychology to molecular biology: explorations into the nature of anxiety. https://app.cochat.ai/papers/10.1176/ajp.140.10.1277
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From metapsychology to molecular biology: explorations into the nature of anxiety. (1983). American Journal of Psychiatry. https://doi.org/10.1176/ajp.140.10.1277

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.