The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Reduction of CO2-induced anxiety in patients with panic attacks after repeated CO2 exposure
Abstract
The authors compared the subjective reaction of 13 panic patients and eight control subjects to a 35% CO2 challenge, a treatment known to produce physical symptoms comparable to those of natural or lactate-induced panic, and to placebo treatment (inhalation of air). They found that patients had higher placebo scores than control subjects, patients tended to get highly anxious on CO2 and control subjects did not, and CO2-induced subjective anxiety in patients decreased as the number of CO2-induced exposures to interoceptive anxiety symptoms increased. The data support a behavioral account of the effects of anxiogenics.
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“There is also experimental evidence that pharmacological interoceptive exposure therapy can reduce anxiety disorder symptom severity either as monotherapy (7,121–123) or as an augmentative approach (124).”
From Interoception and Mental Health: A Roadmap. (2018) · cites this paper as [7]
Citations
Cites
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Cited by
Sorted by citations
Interoception and Mental Health: A Roadmap.
Khalsa, S. S., Adolphs, R., Cameron, O. G., Critchley, H. D., Davenport, P. W., Feinstein, J. S., Feusner, J. D., Garfinkel, S. N., Lane, R. D., Mehling, W. E., et al. (2018) · Biological psychiatry. Cognitive neuroscience and neuroimaging · doi:10.1016/j.bpsc.2017.12.004 · Cited by 1,453
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Metadata
- Authors
- van den Hout, M., van der Molen, G. M., Griez, E. J. L., Lousberg, H., & Nansen, A.
- Venue
- American Journal of Psychiatry
- Published
- 1987-06-01
- Volume
- 144
- Issue
- 6
- Pages
- 788-791
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2409959974
- Cited by
- 107
- References
- 16
- Citations by year
- 2026: 2 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 2
- FWCI
- 10.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Keywords
- panic disorder, CO2 challenge, anxiety, placebo effect, anxiogenic effects, panic attacks
- MeSH terms
- Adolescent, Adult, Anxiety Disorders, Carbon Dioxide, Fear, Female, Habituation, Psychophysiologic, Humans, Lactates, Male, Models, Psychological, Panic, Sensation, Lactic Acid
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