The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Physical Aggression in Dementia Patients and Its Relationship to Depression
Abstract
OBJECTIVE: The goal of this study was to determine the frequency of physically aggressive behavior in community-residing patients with dementia and its relationship to depression. METHOD: A consecutive series of 541 patients with DSM-IV-defined dementia underwent comprehensive neuropsychiatric evaluation and were rated on the Cornell Scale for Depression in Dementia, the Mini-Mental State, the Psychogeriatric Dependency Rating Scale, and the General Medical Health Rating. RESULTS: Physically aggressive behavior was exhibited by 79 patients in the 2 weeks before evaluation. Aggressive behavior was closely associated with moderate to severe depression, male gender, and greater impairment in activities of daily living, even after adjustment for delusions, hallucinations, sleep disturbance, and severity of cognitive impairment. After adjustment for depression, gender, and impairment in activities of daily living, there was no association between physically aggressive behavior and the presence of either delusions or hallucinations. CONCLUSIONS: A substantial minority of patients with dementia exhibit physically aggressive behavior, and this aggression is strongly linked with the presence of depressive symptoms. It is possible that the identification and treatment of depression in dementia may be a means of preventing and managing physically aggressive behavior.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Individuals with impaired physical functioning 23-25 and with dementia and depression 20,26 are at high risk for disturbing behaviors”
From Therapeutic recreation interventions for need-driven dementia-compromised (2002) · cites this paper as [20]
Citations
Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
Román, G. C., Tatemichi, T. K., Erkinjuntti, T., Cummings, J. L., Masdeu, J. C., Garcia, J. H., Amaducci, L., Orgogozo, J.-M., Brun, A., Hofman, A., et al. (1993) · Neurology · doi:10.1212/wnl.43.2.250 · Cited by 4,921
Cornell scale for depression in dementia
Alexopoulos, G. S., Abrams, R. C., Young, R. C., & Shamoian, C. A. (1988) · Biological Psychiatry · doi:10.1016/0006-3223(88)90038-8 · Cited by 2,678
The spectrum of behavioral changes in Alzheimer's disease
Mega, M., Cummings, J., Fiorello, T., & Gornbein, J. (1996) · Neurology · doi:10.1212/wnl.46.1.130 · Cited by 1,124
The Impact of Dementia on the Family
Rabins, P. V. (1982) · JAMA · doi:10.1001/jama.1982.03330030039022 · Cited by 739
Psychiatric Phenomena in Alzheimer's Disease. IV: Disorders of Behaviour
Burns, A., Jacoby, R. J., & Levy, R. (1990) · The British Journal of Psychiatry · doi:10.1192/bjp.157.1.86 · Cited by 391
Troublesome and Disruptive Behaviors in Dementia
Swearer, J. M., Drachman, D. A., O’Donnell, B. F., & Mitchell, A. L. (1988) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1988.tb04260.x · Cited by 357
Double-blind trial of imipramine in Alzheimer's disease patients with and without depression
Reifler, B. V., Teri, L. L., Raskind, M. A., Veith, R. C., Barnes, R., White, E., & McLean, P. (1989) · American Journal of Psychiatry · doi:10.1176/ajp.146.1.45 · Cited by 342
Major and minor depression in Alzheimer's disease: prevalence and impact
Lyketsos, C. G., Steele, C., Baker, L., Galik, E. M., Kopunek, S., Steinberg, M., & Warren, A. (1997) · Journal of Neuropsychiatry · doi:10.1176/jnp.9.4.556 · Cited by 321
Self-citation
Cited by
Sorted by citations
Depression in Late Life: Review and Commentary
Blazer, D. G. (2003) · The Journals of Gerontology Series A · doi:10.1093/gerona/58.3.m249 · Cited by 2,383
Lyketsos, C. G., DelCampo, L., Steinberg, M., Miles, Q., Steele, C. D., Munro, C., Baker, A. S., Sheppard, J.-M. E., Frangakis, C., Brandt, J., et al. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.7.737 · Cited by 398
Self-citationDepression in Alzheimer’s disease: overview and treatment
Lyketsos, C. G., & Olin, J. T. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01348-3 · Cited by 393
Self-citationCholinergic dysfunction in diseases with Lewy bodies
Tiraboschi, P., Hansen, L. A., Alford, M. F., Sabbagh, M. N., Schoos, B., Masliah, E., Thal, L. J., & Corey‐Bloom, J. (2000) · Neurology · doi:10.1212/wnl.54.2.407 · Cited by 332
Psychiatric Symptoms Vary With the Severity of Dementia in Probable Alzheimer's Disease
Lopez, O. L., Becker, J. T., Sweet, R. A., Klunk, W., Kaufer, D. I., Saxton, J., Habeych, M., & DeKosky, S. T. (2003) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.15.3.346 · Cited by 286
Metadata
- Authors
- Lyketsos, C. G., Steele, C., Galik, E., Rosenblatt, A., Steinberg, M., Warren, A., & Sheppard, J.-M.
- Affiliations
- Johns Hopkins University (US)
- Venue
- American Journal of Psychiatry
- Published
- 1999-01-01
- Volume
- 156
- Issue
- 1
- Pages
- 66-71
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2106279983
- Cited by
- 199
- References
- 37
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 4 · 2022: 3 · 2021: 6 · 2020: 9 · 2019: 4 · 2018: 7 · 2017: 2 · 2016: 4 · 2015: 3 · 2014: 8 · 2013: 3 · 2012: 10
- FWCI
- 8.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01mh056511-05)
- National Institute of Mental Health (MH56511)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Social Sciences › Business, Management and Accounting › Organizational Behavior and Human Resource Management › Workplace Violence and Bullying
- Keywords
- physical aggression, dementia, depression, community-dwelling older adults, neuropsychiatric symptoms, activities of daily living, delusions, hallucinations, Cornell Scale for Depression in Dementia, gender differences
- MeSH terms
- Activities of Daily Living, Aged, Aggression, Cross-Sectional Studies, Delusions, Dementia, Depressive Disorder, Female, Hallucinations, Humans, Male, Neuropsychological Tests, Psychiatric Status Rating Scales, Severity of Illness Index, Sex Factors, Comorbidity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
