The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Deficits on a Probabilistic Response-Reversal Task in Patients With Pediatric Bipolar Disorder
Abstract
OBJECTIVE: Patients with bipolar disorder become hyperhedonic when manic and anhedonic when depressed; therefore, it is important to test whether patients with bipolar disorder show deficits on behavioral paradigms exploring reward/punishment mechanisms. METHOD: A probabilistic response-reversal task was administered to 24 bipolar children and 25 comparison subjects. RESULTS: Patients made more errors during probabilistic reversal, took longer to learn the new reward object, and were less likely to meet the learning criterion. CONCLUSIONS: Children with bipolar disorder may have a reversal learning deficit.
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“Behavioral studies of response to rewards in bipolar disorder indicate deficits in behavioral adaptation to changing reward contingencies [267] and prolonged elevation of mood in response to monetary reward in euthymic patients with bipolar disorder [268].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [267]
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Cites
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A Rating Scale for Mania: Reliability, Validity and Sensitivity
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The Orbitofrontal Cortex and Reward
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A Functional Magnetic Resonance Imaging Study of Bipolar Disorder
Blumberg, H. P., Leung, H., Skudlarski, P., Lacadie, C., Fredericks, C. A., Harris, B. C., Charney, D. S., Gore, J. C., Krystal, J. H., & Peterson, B. S. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.6.601 · Cited by 479
A Depression Rating Scale for Children
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Starkstein, S., & Robinson, R. (1997) · Journal of Nervous and Mental Disease · doi:10.1097/00005053-199702000-00007 · Cited by 243
Neuropsychological performance in pediatric bipolar disorder
Dickstein, D. P., Treland, J. E., Snow, J., Tone, E. B., Mehta, M. S., Towbin, K. E., Pine, D. S., & Leibenluft, E. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00701-7 · Cited by 197
Self-citationUnderstanding the neurobiology of emotion perception: implications for psychiatry
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Phillips, M. L., Ladouceur, C. D., & Drevets, W. C. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.65 · Cited by 1,383
Blair, R. J. R. (2005) · Consciousness and Cognition · doi:10.1016/j.concog.2005.06.004 · Cited by 1,365
Dichter, G. S., Damiano, C. A., & Allen, J. A. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-19 · Cited by 299
Frontotemporal Alterations in Pediatric Bipolar Disorder
Dickstein, D. P., Milham, M. P., Nugent, A. C., Drevets, W. C., Charney, D. S., Pine, D. S., & Leibenluft, E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.7.734 · Cited by 258
Self-citationDevelopment of the uncinate fasciculus: Implications for theory and developmental disorders
Olson, I. R., Heide, R. J. V. D., Alm, K. H., & Vyas, G. (2015) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2015.06.003 · Cited by 244
Metadata
- Authors
- Gorrindo, T., Blair, R. J. R., Budhani, S., Dickstein, D. P., Pine, D. S., & Leibenluft, E.
- Affiliations
- National Institute of Mental Health (US)
- Venue
- American Journal of Psychiatry
- Published
- 2005-10-01
- Volume
- 162
- Issue
- 10
- Pages
- 1975-1977
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2110855184
- Cited by
- 111
- References
- 11
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 1 · 2021: 6 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 6 · 2016: 7 · 2015: 12 · 2014: 6 · 2013: 7 · 2012: 9
- FWCI
- 6.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- pediatric bipolar disorder, probabilistic reversal learning, reward learning, punishment learning, anhedonia, learning deficits
- MeSH terms
- Adolescent, Affective Symptoms, Age Factors, Bipolar Disorder, Child, Female, Frontal Lobe, Humans, Learning Disabilities, Male, Psychomotor Performance, Reversal Learning, Prefrontal Cortex
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