The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Internet-Delivered Treatment for Substance Abuse: A Multisite Randomized Controlled Trial
Open accessAbstract
OBJECTIVE: Computer-delivered interventions have the potential to improve access to quality addiction treatment care. The objective of this study was to evaluate the effectiveness of the Therapeutic Education System (TES), an Internet-delivered behavioral intervention that includes motivational incentives, as a clinician-extender in the treatment of substance use disorders. METHOD: Adult men and women (N=507) entering 10 outpatient addiction treatment programs were randomly assigned to receive 12 weeks of either treatment as usual (N=252) or treatment as usual plus TES, with the intervention substituting for about 2 hours of standard care per week (N=255). TES consists of 62 computerized interactive modules covering skills for achieving and maintaining abstinence, plus prize-based motivational incentives contingent on abstinence and treatment adherence. Treatment as usual consisted of individual and group counseling at the participating programs. The primary outcome measures were abstinence from drugs and heavy drinking (measured by twice-weekly urine drug screens and self-report) and time to dropout from treatment. RESULTS: Compared with patients in the treatment-as-usual group, those in the TES group had a lower dropout rate (hazard ratio=0.72, 95% CI=0.57, 0.92) and a greater abstinence rate (odds ratio=1.62, 95% CI=1.12, 2.35). This effect was more pronounced among patients who had a positive urine drug or breath alcohol screen at study entry (N=228) (odds ratio=2.18, 95% CI=1.30, 3.68). CONCLUSIONS: Internet-delivered interventions such as TES have the potential to expand access and improve addiction treatment outcomes. Additional research is needed to assess effectiveness in non-specialty clinical settings and to differentiate the effects of the community reinforcement approach and contingency management components of TES.
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“The validation study of the application, performed with 507 people, demonstrated that the use of the application was associated with more days of abstinence and a lower rate of attrition than in the treatment-as-usual condition (98).”
From Mobile intervention for individuals with psychosis, dual disorders, and their common comorbidities: A literature review (2019) · cites this paper as [98]
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“It is important to mention that this study, which served as justification for the approval of the application by the FDA, was performed on a desktop-based intervention, which was subsequently adapted to the format of a mobile application (97, 98).”
From Mobile intervention for individuals with psychosis, dual disorders, and their common comorbidities: A literature review (2019) · cites this paper as [98]
Experimental — accuracy not yet measuredIn the citing paper
“Similarly, two DTx that received FDA clearance as SaMD for the adjunctive treatment of opioid use and substance use disorder (8, 46) used TAU or reduced TAU as comparators (see Table 1 for a description of the reduced TAU versus full TAU condition) (8).”
In the citing paper
“In addition, some of the studies reported the conclusion in ambiguous language, such as a treatment ‘may be effective [19, 27]’, or has ‘the potential [28]’.”
From Overstatements in abstract conclusions claiming effectiveness of interventions in psychiatry: A meta-epidemiological investigation (2017) · cites this paper as [28]
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“In contrast, some (36), although not all (37), studies of CBT for addictions have observed that the benefits of the intervention actually increased after treatment, suggesting, as one would hope, that the patients learned skills that they continue to practice and benefit from over time.”
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Metadata
- Authors
- Campbell, A. N. C., Nunes, E. V., Matthews, A. G., Stitzer, M., Miele, G. M., Polsky, D., Turrigiano, E., Walters, S., McClure, E. A., Kyle, T. L., Wahle, A., Van Veldhuisen, P., Goldman, B., Babcock, D., Stabile, P. Q., Winhusen, T., & Ghitza, U. E.
- Affiliations
- St. Luke's-Roosevelt Hospital Center (US)
- From New York State Psychiatric Institute, New York; Department of Psychiatry, Columbia University, New York; Department of Psychiatry and Behavioral Health, St. Luke’s Roosevelt Hospital Center, New York; EMMES Corporation, Rockville, Md.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore; School of Medicine, University of Pennsylvania, Philadelphia; School of Public Health, University of North Texas Health Science Center, Fort Worth; Clinical...
- ORCID
- Venue
- American Journal of Psychiatry
- Published
- 2014-06
- Volume
- 171
- Issue
- 6
- Pages
- 683-690
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- PMC
- PMC4079279
- OpenAlex
- W1963819178
- Cited by
- 263
- References
- 38
- Citations by year
- 2026: 18 · 2025: 15 · 2024: 23 · 2023: 26 · 2022: 30 · 2021: 27 · 2020: 28 · 2019: 23 · 2018: 19 · 2017: 15 · 2016: 17 · 2015: 15 · 2014: 6
- FWCI
- 13.38
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5u10da013034-15)
- National Institute on Drug Abuse (U10DA013720, U10DA013035, K24DA022412, DA013035, U10-DA013034, U10DA013732, U10DA015815, U10DA020024, U10DA013036, U10DA013714, U10DA015831, DA015831, UG1DA020024)
- National Institute on Minority Health and Health Disparities (L60 MD006644)
- National Drug Abuse Treatment Clinical Trials Network
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Keywords
- internet-delivered treatment, substance use disorders, motivational incentives, abstinence, treatment discontinuation, outpatient addiction treatment, community reinforcement, contingency management, access to addiction treatment
- MeSH terms
- Adult, Behavior Therapy, Female, Humans, Male, Patient Compliance, Treatment Outcome, Telemedicine, Substance-Related Disorders, Internet
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