The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior
Open accessAbstract
OBJECTIVE: Increased risk of psychopathology is observed in children exposed to maternal prenatal distress, and elevated maternal cortisol and epigenetic regulation of placental glucocorticoid-pathway genes are potential mechanisms. The authors examined maternal distress and salivary cortisol in relation to fetal movement and heart rate ("coupling") and DNA methylation of three glucocorticoid pathway genes-HSD11B2, NR3C1, and FKBP5-in term placentas. METHOD: Mood questionnaires and salivary cortisol were collected from 61 women between 24-27 gestational weeks, and fetal assessment was conducted at 34-37 weeks. Placental CpG methylation in the three genes was analyzed using 450K Beadchips and bisulfite sequencing; correlations between maternal and fetal variables and DNA methylation were tested; and maternal distress effects on fetal behavior via DNA methylation were investigated. RESULTS: Perceived stress (Perceived Stress Scale), but not cortisol, was associated with altered CpG methylation in placentas. In the highest tertile of the Perceived Stress Scale, the Beadchip data revealed modestly elevated methylation of HSD11B2, associated with lower fetal coupling (β=-0.51), and modestly elevated methylation of FKBP5, also with lower fetal coupling (β=-0.47). These increases in methylation were validated by bisulfite sequencing, where they occurred in a minority of clones. CONCLUSIONS: This is the first study to link the effects of pregnant women's distress on the fetus and epigenetic changes in placental genes. Since increased DNA methylation in HSD11B2 and FKBP5 are seen in a minority of bisulfite sequencing clones, these epigenetic changes, and functional consequences, may affect subpopulations of placental cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Placental hypermethylation across NR3C1 and FKBP5 has been associated with higher second trimester perceived stress and increased anxious and depressive symptoms, in case of FKBP5 in 61 women (Monk et al., 2016)”
From The applied implications of epigenetics in anxiety, affective and stress-related disorders - A review and synthesis on psychosocial stress, psychotherapy and prevention (2020) · cites this paper as Monk et al., 2016
The cited source says what the claim attributes to it.
In the citing paper
“perceived stress was associated with increased FKBP5 methylation which in turn was associated with lower third trimester fetal coupling (correlation of fetal movement and heart rate; indicative of CNS maturation), denoting an epigenetic link between pregnancy stress and fetal development (Monk et al., 2016)”
From The applied implications of epigenetics in anxiety, affective and stress-related disorders - A review and synthesis on psychosocial stress, psychotherapy and prevention (2020) · cites this paper as Monk et al., 2016
The cited source says what the claim attributes to it.
In the citing paper
“↑ FKBP5 methylation associated with increased perceived stress”
From The applied implications of epigenetics in anxiety, affective and stress-related disorders - A review and synthesis on psychosocial stress, psychotherapy and prevention (2020) · cites this paper as Monk et al., 2016
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Global Measure of Perceived Stress
Cohen, S., Kamarck, T., & Mermelstein, R. (1983) · Journal of Health and Social Behavior · doi:10.2307/2136404 · Cited by 32,807
The assessment of anxiety states by rating
HAMILTON, M. (1959) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1959.tb00467.x · Cited by 11,455
Wilamowska (2010) · doi:10.1001/archpsyc.1988.01800320058007 · Cited by 2,115
Binder, E. B. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.05.021 · Cited by 968
Early Life Programming and Neurodevelopmental Disorders
Bale, T. L., Baram, T. Z., Brown, A. S., Goldstein, J. M., Insel, T. R., McCarthy, M. M., Nemeroff, C. B., Reyes, T. M., Simerly, R. B., Susser, E. S., et al. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.05.028 · Cited by 961
Glucocorticoids and fetal programming part 1: outcomes
Moisiadis, V. G., & Matthews, S. G. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.73 · Cited by 586
Epigenetic and transgenerational reprogramming of brain development
Bale, T. L. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3818 · Cited by 505
Maternal prenatal anxiety and downregulation of placental 11β-HSD2
O’Donnell, K. J., Bugge Jensen, A., Freeman, L., Khalife, N., O’Connor, T. G., & Glover, V. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.09.014 · Cited by 449
Glover, V. A. S. (2014) · Advances in neurobiology · doi:10.1007/978-1-4939-1372-5_13 · Cited by 422
Peña, C. J., Monk, C. E., & Champagne, F. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039791 · Cited by 377
Self-citation
Cited by
Sorted by citations
Items 101–200 of 319
Hong, X., Bartell, T. R., & Wang, X. (2020) · Pediatric Research · doi:10.1038/s41390-020-01266-9 · Cited by 23
Morgan, J., Channon, S., Penny, H., & Waters, C. S. (2019) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-019-01447-w · Cited by 23
How do maternal emotion and sleep conditions affect infant sleep: a prospective cohort study
Lin, X., Zhai, R., Mo, J., Sun, J., Chen, P., & Huang, Y. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-04504-6 · Cited by 20
Dockx, Y., Bijnens, E. M., Saenen, N. D., Aerts, R., Aerts, J., Casas, L., Delcloo, A., Dendoncker, N., Linard, C., Plusquin, M., et al. (2022) · Epigenetics · doi:10.1080/15592294.2022.2088464 · Cited by 23
Broeks, C. W., Molenaar, N. M., Brouwer, M. E., van den Akker, E. L. T., van Rossum, E. F. C., Van, R., van den Berg, S. A. A., Hillegers, M. H. J., Hoogendijk, W. J. G., Burger, H., et al. (2023) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2023.100167 · Cited by 20
Short, A. K., Weber, R., Kamei, N., Thai, C. W., Arora, H., Mortazavi, A., Stern, H. S., Glynn, L. M., & Baram, T. Z. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100652 · Cited by 21
Azar, N., & Booij, L. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.09.008 · Cited by 23
Wiley, K. S., Camilo, C., Gouveia, G. R., Euclydes, V. L. V., Panter‐Brick, C., Matijasevich, A., Ferraro, A. A., Fracolli, L. A., Chiesa, A. M., Miguel, E. C., et al. (2022) · Developmental Psychobiology · doi:10.1002/dev.22352 · Cited by 22
Nazzari, S., Grumi, S., Biasucci, G., Decembrino, L., Fazzi, E. M., Giacchero, R., Magnani, M. L., Nacinovich, R., Scelsa, B., Spinillo, A., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0284578 · Cited by 19
Gao, M. M., Saenz, C., Neff, D., Santana, M. L., Amici, J., Butner, J., Raby, K. L., Crowell, S. E., & Conradt, E. D. (2021) · Journal of Health Psychology · doi:10.1177/13591053211064984 · Cited by 18
Trajectories of brain and behaviour development in the womb, at birth and through infancy
Weiss, S. M., Aydin, E., Lloyd‐Fox, S., & Johnson, M. H. (2024) · Nature Human Behaviour · doi:10.1038/s41562-024-01896-7 · Cited by 22
Castro-Quintas, Á., Palma‐Gudiel, H., Eixarch, E., Martín-González, N. S., Röh, S., Sauer, S., Rex‐Haffner, M., Garcia, J. L. M., de la Fuente-Tomás, L., Crispi, F., et al. (2024) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2024.10.001 · Cited by 18
Conradt, E. D., Adkins, D. E., Crowell, S. E., Monk, C. E., & Kobor, M. S. (2018) · Development and Psychopathology · doi:10.1017/s0954579418000688 · Cited by 16
Self-citationHerzberg, M. P., & Smyser, C. D. (2024) · Pediatric Research · doi:10.1038/s41390-024-03345-7 · Cited by 19
Ünsel‐Bolat, G., Yıldırım, S., Kılıçaslan, F., & Caparrós-González, R. A. (2024) · Behavioral Sciences · doi:10.3390/bs14111054 · Cited by 15
Placental Studies for Child Development
O’Connor, T. G., Miller, R. K., & Salafia, C. M. (2019) · Child Development Perspectives · doi:10.1111/cdep.12338 · Cited by 16
Lamadé, E. K., Hendlmeier, F., Wudy, S. A., Witt, S. H., Rietschel, M., Coenen, M., Gilles, M., & Deuschle, M. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab113 · Cited by 15
Bleker, L. S., Milgrom, J., Sexton‐Oates, A., Parker, D., Roseboom, T. J., Gemmill, A. W., Holt, C. J., Saffery, R., Connelly, A., Burger, H., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00034 · Cited by 16
Maternal corticosteroids and depression during gestation and decreased fetal heart rate variability
Hunter, S. K., Freedman, R., Law, A. J., Christians, U., Holzman, J. B. W., Johnson, Z., & Hoffman, M. C. (2021) · Neuroreport · doi:10.1097/wnr.0000000000001711 · Cited by 14
Stigma as a Source of Stress for Adolescent Mothers and Their Babies
Wittenberg, J. P., Flaherty, L. T., Becker, D. F., Harper, G. P., Crookall, J. M., & Vianna, N. (2022) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000001545 · Cited by 14
Tartour, A. I., Chivese, T., Eltayeb, S., Elamin, F. M., Fthenou, E., Ahmed, M. S., & Babu, G. R. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2024.107060 · Cited by 16
Cariaga-Martínez, A. E., Gutiérrez, K. J., & Alelú‐Paz, R. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19051333 · Cited by 14
Martinez-Serrano, C. A., Marteinsdóttir, Í., Josefsson, A., Sydsjö, G., Theodorsson, E., & Rodríguez‐Martínez, H. (2020) · Genes · doi:10.3390/genes11080869 · Cited by 13
Infant Emotion Development and Temperament
Aktar, E., & Pérez‐Edgar, K. E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.026 · Cited by 17
Prenatal social support in low-risk pregnancy shapes placental epigenome
Tesfaye, M., Wu, J., Biedrzycki, R. J., Grantz, K. L., Joseph, P. V., & Ayele, F. T. (2023) · BMC Medicine · doi:10.1186/s12916-022-02701-w · Cited by 16
Srividhya, D., Korlimarla, A., Ravikumar, G., Snijesh, V. P., Kaku, S. M., & Visweswariah, A. M. (2022) · Birth Defects Research · doi:10.1002/bdr2.2119 · Cited by 15
Midlife reversibility of early-established biobehavioral risk factors: A research agenda.
Reiss, D., Nielsen, L. O., Godfrey, K. M., McEwen, B. S., Power, C., Seeman, T. E., & Suomi, S. J. (2019) · Developmental Psychology · doi:10.1037/dev0000780 · Cited by 15
Success Stories: Overcoming Barriers to Research in Southern and Eastern African Countries
Sun, C., Dlamini, P. S., Maimbolwa, M., Mukonka, C. C. L., Nyamakura, R., Omoni, G. M., Seboni, N. M., & Larson, E. (2017) · Clinical Nursing Research · doi:10.1177/1054773817718935 · Cited by 13
Greenspace, stress, and health: how is epigenetics involved?
Nwanaji‐Enwerem, U., McGeary, J. E., & Grigsby‐Toussaint, D. S. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1333737 · Cited by 12
Gustafsson, H., Goodman, S. H., Feng, T., Choi, J., Lee, S., Newport, D. J., Knight, B. T., Pingeton, B. C., Stowe, Z. N., & Monk, C. E. (2018) · Development and Psychopathology · doi:10.1017/s0954579418000639 · Cited by 12
Self-citationBroeks, C. W., Choenni, V., Kok, R., van der Voorn, B., de Kruijff, I., van den Akker, E. L. T., van Rossum, E. F. C., Hoogendijk, W. J. G., Hillegers, M. H. J., Kamperman, A. M., et al. (2021) · BJPsych Open · doi:10.1192/bjo.2020.159 · Cited by 12
A perspective-based analysis of attachment from prenatal period to second year postnatal life
Santaguida, E., & Bergamasco, M. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1296242 · Cited by 15
Torres-Salazar, Q. L., Martínez-López, Y., Reyes-Romero, M. A., Pérez–Morales, R., Sifuentes-Álvarez, A., & Salvador‐Moysén, J. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00206 · Cited by 11
Cross-Cultural Perspectives on Parent–Infant Interactions
Bornstein, M. H., & Esposito, G. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.029 · Cited by 12
The Developmental Effects of Prenatal Maternal Stress: Evolutionary Explanations
Herba, C. M., & Glover, V. A. S. (2021) · Springer eBooks · doi:10.1007/978-3-030-60159-1_3 · Cited by 13
Champagne, F. A. (2017) · Palgrave Macmillan UK eBooks · doi:10.1057/978-1-137-52879-7_10 · Cited by 11
Self-citationGiarratano, G., Bernard, M. L., & Orlando, S. (2019) · The Journal of Perinatal & Neonatal Nursing · doi:10.1097/jpn.0000000000000419 · Cited by 11
Intergenerational transmission of stress vulnerability and resilience
Bowers, M. E., & Yehuda, R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813983-7.00017-3 · Cited by 11
Stonawski, V., Frey, S., Golub, Y., Moll, G. H., Heinrich, H., & Eichler, A. (2017) · Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie · doi:10.1024/1422-4917/a000515 · Cited by 14
Prenatal influences on the development and stability of personality
Krzeczkowski, J. E., & Lieshout, R. J. V. (2018) · New Ideas in Psychology · doi:10.1016/j.newideapsych.2018.01.003 · Cited by 13
Müller, S., Moser, D., Frach, L., Wimberger, P., Nitzsche, K. I., Li, S., Kirschbaum, C., & Alexander, N. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01828-x · Cited by 9
Finik, J. M., Buthmann, J. L., Zhang, W., Go, K. A., & Nomura, Y. (2020) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-020-00632-9 · Cited by 10
The Impact of Stress Within and Across Generations: Neuroscientific and Epigenetic Considerations
Miller, C. W. T. (2021) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000300 · Cited by 13
Mindful Digital Program–based Interventions and their Role in Pregnancy and Fetal Outcomes
Malhotra, J., Malhotra, N., Patil, M., Malhotra, N., & Garg, R. (2021) · Journal of South Asian Federation of Obstetrics and Gynaecology · doi:10.5005/jp-journals-10006-1909 · Cited by 10
Curtailing the communicability of psychiatric disorders
Wainberg, M. L., Helpman, L., Duarte, C. S., Vermund, S. H., Mootz, J. J., Gouveia, L., Oquendo, M. A., McKinnon, K. M., & Cournos, F. (2018) · The Lancet Psychiatry · doi:10.1016/s2215-0366(18)30342-0 · Cited by 12
The role of epigenetics in social psychiatry
Peedicayil, J. (2016) · International Journal of Social Psychiatry · doi:10.1177/0020764016677556 · Cited by 10
Imanishi, Y., Ikehara, S., Aochi, Y., Sobue, T., Iso, H., & The Japan Environment and Children’s Study Group (2024) · Environmental Health and Preventive Medicine · doi:10.1265/ehpm.23-00211 · Cited by 9
Evidence for neurobehavioral risk phenotypes at birth
Conradt, E. D., Tronick, E. Z., & Lester, B. M. (2024) · Pediatric Research · doi:10.1038/s41390-024-03353-7 · Cited by 9
Prenatal depression and successful lactation
Syam, A., Iskandar, I., Hendrarti, W., & Salam, A. (2021) · Medicina Clínica Práctica · doi:10.1016/j.mcpsp.2021.100234 · Cited by 11
Equity for Children in the United States
Meek, S. E., Catherine, E., Soto-Boykin, X. T., & Blevins, D. (2024) · Cambridge University Press eBooks · doi:10.1017/9781009379755 · Cited by 8
Added sugar intake during pregnancy: Fetal behavior, birth outcomes, and placental DNA methylation
Trumpff, C., Sturm, G., Picard, M. A., Foss, S., Lee, S., Feng, T., Cárdenas, A., McCormack, C. A., Champagne, F. A., & Monk, C. E. (2021) · Developmental Psychobiology · doi:10.1002/dev.22088 · Cited by 9
Self-citationEaves, L. A., Enggasser, A. E., Camerota, M., Gogcu, S., Gower, W. A., Hartwell, H. J., Jackson, W., Jensen, E. T., Joseph, R. M., Marsit, C. J., et al. (2022) · Pediatric Research · doi:10.1038/s41390-022-02150-4 · Cited by 12
Richards, J. E., & Conte, S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.004 · Cited by 12
Siller, S., Heidinger, B. J., Westneat, D. F., Solomon, J. W., & Rubenstein, D. R. (2024) · Molecular Ecology · doi:10.1111/mec.17291 · Cited by 9
Stonawski, V., Roetner, J., Goecke, T. W., Fasching, P. A., Beckmann, M. W., Kornhuber, J., Kratz, O., Moll, G. H., Eichler, A., Heinrich, H., et al. (2020) · Epigenetics Insights · doi:10.1177/2516865720932146 · Cited by 9
Rachwani, J., Hoch, J. E., & Adolph, K. E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.017 · Cited by 9
Prenatal Lead and Depression Exposures Jointly Influence Birth Outcomes and NR3C1 DNA Methylation
Appleton, A. A., Kiley, K., Schell, L. M., Holdsworth, E. A., Akinsanya, A., & Beecher, C. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182212169 · Cited by 8
Periconception and Prenatal Exposure to Maternal Perceived Stress and Cord Blood DNA Methylation
Polinski, K. J., Putnick, D. L., Robinson, S. L., Schliep, K. C., Silver, R. M., Guan, W., Schisterman, E. F., Mumford, S. L., & Yeung, E. H. (2022) · Epigenetics Insights · doi:10.1177/25168657221082045 · Cited by 8
Infant Object Manipulation and Play
Tamis‐LeMonda, C. S., & Lockman, J. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.019 · Cited by 8
The interplay between DNA methylation and cardiac autonomic system functioning: a systematic review
Oliveira, N. C. D. S., Serpeloni, F., & de Assis, S. G. (2021) · International Journal of Environmental Health Research · doi:10.1080/09603123.2021.2000590 · Cited by 8
Negative associations between maternal prenatal hair cortisol and child socioemotional problems
Mustonen, P., Kortesluoma, S., Scheinin, N. M., Perasto, L., Kataja, E., Tervahartiala, K., Tuulari, J. J., Coimbra, B., Carter, A. S., Rodrigues, A. J., et al. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2023.106955 · Cited by 7
van Dijk, M. T., Talati, A., Gonzalez-Barrios, P., Crandall, A. J., & Lugo-Candelas, C. I. (2024) · Seminars in Perinatology · doi:10.1016/j.semperi.2024.151948 · Cited by 10
Schwank, S. E., Chung, H.-F., Hsu, M., Fu, S.-C., Du, L., Zhu, L., Huang, H.-Y., Andersson, E. P., & Acharya, G. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-041133 · Cited by 8
Dong, Y., Weng, J., Zhu, Y., Sun, D., He, W., Chen, Q., Cheng, J., Zhu, Y., & Jiang, Y. (2023) · BMC Genomics · doi:10.1186/s12864-023-09186-8 · Cited by 9
DNA methylation studies of depression with onset in the peripartum: A critical systematic review
Braun, S. E., Lapato, D. M., Brown, R., Lancaster, E. E., York, T. P., Amstadter, A. B., & Kinser, P. A. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.04.005 · Cited by 8
Stress and its effects across generations
Engmann, O., & Mansuy, I. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813983-7.00018-5 · Cited by 7
Infant Vocal Learning and Speech Production
Warlaumont, A. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.022 · Cited by 10
The Development of Infant Feeding
Mennella, J. A., Forestell, C. A., Ventura, A. K., & Fisher, J. O. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.010 · Cited by 7
Singla, D. R., Lawson, A., Dennis, C., Kaliush, P. R., Walsh, K., Patel, V., & Schiller, C. E. (2025) · Nature Reviews Psychology · doi:10.1038/s44159-025-00505-2 · Cited by 6
The cyclical and intergenerational effects of perinatal domestic abuse and mental health
Moncrieff, G. (2018) · British Journal of Midwifery · doi:10.12968/bjom.2018.26.2.85 · Cited by 6
Robakis, T. K., Lee, S., Werner, E. A., Liu, G., Miller, M., Wylie, D., Champagne, F. A., Salas, M. C., Do, C., Tycko, B., et al. (2020) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2020.100044 · Cited by 6
Self-citationThe effects of stress on early brain and behavioral development
Noroña, A. N., Doom, J. R., Davis, E. P., & Gunnar, M. R. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-814411-4.00026-3 · Cited by 7
Yang, J., Xu, A., Zhang, Y., Deng, J., Lin, X., Xie, L., Deng, X., Liu, H., Chen, P., & Huang, Y. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-05066-3 · Cited by 6
Maternal childhood trauma and observed maternal care behaviors with 4-month-old infants.
VanBronkhorst, S. B., McCormack, C. A., Scorza, P., Lee, S., Feng, T., Hane, A. A., Duarte, C. S., & Monk, C. E. (2023) · Psychological Trauma Theory Research Practice and Policy · doi:10.1037/tra0001554 · Cited by 6
Self-citationZhang, T., Wang, H., Ouyang, F., Yang, H., Zhang, J., & Zhang, N. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.05.074 · Cited by 7
Infant Attachment (to Mother and Father) and Its Place in Human Development
Dagan, O., & Sagi‐Schwartz, A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.025 · Cited by 6
Stress, the Placenta, and Fetal Programming of Behavior: Genes’ First Encounter With the Environment
Hoffman, M. C. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16050502 · Cited by 6
Freedman, R., Hunter, S. K., Noonan, K., Wyrwa, A., Christians, U., Law, A. J., & Hoffman, M. C. (2021) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2020.08.003 · Cited by 19
Domenico, C. D., Calderone, A., Latella, D., Luca, R. D., Corallo, F., Cucinotta, F., Cardile, D., Quartarone, A., Militi, A., & Calabrò, R. S. (2025) · BMJ Open · doi:10.1136/bmjopen-2025-104716 · Cited by 8
Bhat, V., Joober, R., & Sengupta, S. M. (2017) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2016.12.016 · Cited by 5
Cohen, N., Defina, S., Rifas‐Shiman, S. L., Faleschini, S., Kirby, R. S., Chen, H., Wilson, R. E., Fryer, K. E., Marroun, H. E., Cecil, C. A. M., et al. (2023) · BMC Pediatrics · doi:10.1186/s12887-023-04372-9 · Cited by 5
Neuroepigenetics of Prenatal Psychological Stress
Claes, S. J. (2018) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2018.04.007 · Cited by 6
Understanding and Evaluating the Moral World in Infancy
Hamlin, J. K., & Sitch, M. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.028 · Cited by 6
Jones, K., Acevedo, B. P., Avalos, L. A., Baker, B. H., Bush, N. R., Buß, C., Grosvenor, L. P., Hipwell, A. E., Marceau, K., McEvoy, C. T., et al. (2025) · Current Zoology · doi:10.1093/eep/dvaf024 · Cited by 8
Prenatal and Early Postnatal Influences on Neurodevelopment: The Role of Epigenetics
Mariotti, V., Palumbo, S., & Pellegrini, S. (2019) · Springer eBooks · doi:10.1007/978-3-030-25816-0_6 · Cited by 5
Shah, R., Salafia, C. M., Girardi, T., Rukat, C., Brunner, J., Barrett, E. S., O’Connor, T. G., Misra, D. P., & Miller, R. K. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.05.108 · Cited by 3
Huang, Q., Shire, D., Hollis, F., Abuaish, S., Picard, M. A., Monk, C. E., Duman, E. A., & Trumpff, C. (2024) · Mitochondrion · doi:10.1016/j.mito.2025.102057 · Cited by 5
Self-citationNeurobiologia delle relazioni interpersonali fattori di rischio di malattia
Verrocchio, M. C., Marchetti, D., & Porcelli, P. (2018) · MALTRATTAMENTO E ABUSO ALL INFANZIA · doi:10.3280/mal2018-003002 · Cited by 4
Naya, C. H., Toledo‐Corral, C. M., Chavez, T., Lerner, D. L., Lurvey, N., Eckel, S. P., Peterson, A. K., Grubbs, B. H., Dunton, G. F., Breton, C. V., et al. (2021) · International Journal of Obesity · doi:10.1038/s41366-021-01009-8 · Cited by 4
Shih, P., Huang, C., Chiang, T., Chen, P., & Guo, Y. L. (2022) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-021-01821-9 · Cited by 4
Curley, J. P., Rahia Mashoodh, A., & Champagne, F. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805388-1.00024-9 · Cited by 4
Self-citationMitsven, S. G., Messinger, D. S., Moffitt, J., & Ahn, Y. A. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.027 · Cited by 6
Curley, J. P., Rahia Mashoodh, A., & Champagne, F. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91909-8.00023-2 · Cited by 4
Self-citationSandberg, L. S., & Busch, F. (2017) · Neuropsychoanalysis · doi:10.1080/15294145.2017.1295217 · Cited by 4
Outlaw, F. H., Milam, L., & Bradley, P. K. (2021) · doi:10.1002/9781119487593.ch8 · Cited by 4
Regulation of the brain-placental axis, and its relevance to the health and disease of the offspring
Behura, S. K. (2025) · Systems Biology in Reproductive Medicine · doi:10.1080/19396368.2025.2567543 · Cited by 3
Les stress pendant les 1 000 premiers jours de la vie quand tout commence
Verney, C., & Vitalis, T. (2023) · médecine/sciences · doi:10.1051/medsci/2023124 · Cited by 3
Champagne, F. A., Dosanjh, L. H., & Firestein, M. R. (2024) · Springer eBooks · doi:10.1007/978-3-031-48627-2_9 · Cited by 3
Self-citationJayaraman, S., & Smith, L. B. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108351959.020 · Cited by 2
Dobrokhotova, Y. E., Fomina, D. S., Pashchenko, A. A., Kruglova, T. S., & Николаевна, Б. Е. (2021) · Russian Journal of Human Reproduction · doi:10.17116/repro20212703178 · Cited by 3
Metadata
- Authors
- Monk, C., Feng, T., Lee, S., Krupska, I., Champagne, F. A., & Tycko, B.
- Affiliations
- Columbia University Irving Medical Center (US)
- Venue
- American Journal of Psychiatry
- Published
- 2016-07-01
- Volume
- 173
- Issue
- 7
- Pages
- 705-713
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- PMC
- PMC5026410
- OpenAlex
- W2304339492
- Cited by
- 304
- References
- 40
- Citations by year
- 2026: 17 · 2025: 22 · 2024: 32 · 2023: 19 · 2022: 28 · 2021: 39 · 2020: 61 · 2019: 21 · 2018: 32 · 2017: 23 · 2016: 10
- FWCI
- 28.43
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH092580)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
- Keywords
- maternal distress, prenatal stress, placenta, DNA methylation, glucocorticoid pathway, 11β-hydroxysteroid dehydrogenase type 2, NR3C1, FKBP5, fetal heart rate, fetal movement, fetal neurobehavior, salivary cortisol, epigenetic regulation
- MeSH terms
- Tacrolimus Binding Protein 5, Adolescent, Adult, Anxiety Disorders, Arousal, Depressive Disorder, Female, Fetal Movement, Heart Rate, Fetal, Humans, Hydrocortisone, Infant, Newborn, Placenta, Pregnancy, Pregnancy Trimester, Third, Prenatal Exposure Delayed Effects, Receptors, Glucocorticoid, CpG Islands, DNA Methylation, Mood Disorders, Tacrolimus Binding Proteins, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Epigenesis, Genetic, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
