Cited by 256Mental Health and PsychiatryTreatment of Major DepressionPsychology and Mental Health

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index; 1 of the 10 sources its claims cite were checked for support.

The Phenomenology of Major Depression and the Representativeness and Nature of DSM Criteria.

Open access
Kendler, Kenneth S.·2016·American Journal of Psychiatry

Abstract

How should DSM criteria relate to the disorders they are designed to assess? To address this question empirically, the author examines how well DSM-5 symptomatic criteria for major depression capture the descriptions of clinical depression in the post-Kraepelin Western psychiatric tradition as described in textbooks published between 1900 and 1960. Eighteen symptoms and signs of depression were described, 10 of which are covered by the DSM criteria for major depression or melancholia. For two symptoms (mood and cognitive content), DSM criteria are considerably narrower than those described in the textbooks. Five symptoms and signs (changes in volition/motivation, slowing of speech, anxiety, other physical symptoms, and depersonalization/derealization) are not present in the DSM criteria. Compared with the DSM criteria, these authors gave greater emphasis to cognitive, physical, and psychomotor changes, and less to neurovegetative symptoms. These results suggest that important features of major depression are not captured by DSM criteria. This is unproblematic as long as DSM criteria are understood to index rather than constitute psychiatric disorders. However, since DSM-III, our field has moved toward a reification of DSM that implicitly assumes that psychiatric disorders are actually just the DSM criteria. That is, we have taken an index of something for the thing itself. For example, good diagnostic criteria should be succinct and require minimal inference, but some critical clinical phenomena are subtle, difficult to assess, and experienced in widely varying ways. This conceptual error has contributed to the impoverishment of psychopathology and has affected our research, clinical work, and teaching in some undesirable ways.

Overview

Integrity signals

Registry

Crossref · 10.1176/appi.ajp.2016.15121509

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

31 Own result · 20 Own interpretation · 20 No basis given · 6 No full text of the sources · 2 Sources not found · 2 Not checked yet · 1 Supported

Show all 41 claims

  • Probably not a substantial claim. 24
  • It may state two separate claims as one. 26
41 of 41
  • The paper relies on this without support.

    Textbooks are the best place to obtain expert opinion about the important symptoms and signs of depression.

    “I focus initially on textbooks as the best place to obtain expert opinion about the important symptoms and signs of depression.”
  • The paper relies on this without support.

    The 19 selected textbooks are representative of the post-Kraepelinian Western psychiatric tradition circa 1900-1960.

    “In total, 19 textbooks, published from 1899 to 1956 from five countries (nine from the United States, seven from the United Kingdom, and one each from Germany, France, and Switzerland), met inclusion criteria.”
  • The paper relies on this without support.

    The textbook descriptions and Lewis's cases accurately reflect the phenomenology of depressive illness or major depression.

    “I next review the phenomenology of depression described by Aubrey Lewis in what is the most detailed survey of the phenomenology of depression written in the 20th century (7).”
  • The paper relies on this without support.

    Lewis's monograph is the most detailed survey of the phenomenology of depression written in the 20th century.

    “I next review the phenomenology of depression described by Aubrey Lewis in what is the most detailed survey of the phenomenology of depression written in the 20th century (7).”
  • The paper relies on this without support.

    The 19 textbooks examined are representative of the Western post-Kraepelinian psychiatric tradition.

    “The DSM symptomatic criteria for major depression do a reasonable but incomplete job of assessing the prominent clinical symptoms and signs of depressive illness as described in the Western post-Kraepelinian psychiatric tradition.”
5 of 5

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

3 of 3

Citations

Cites

Show all 42 references

Research works printed but not linked: 4

  1. Burton R, 1893, The Anatomy of Melancholia
  2. White WA, 1913, Outlines of Psychiatry: Nervous and Mental Disease Monograph Series No 1
  3. Mayer-Gross W, 1954, Clinical Psychiatry
  4. Spitzer RL, 1975, Research Diagnostic Criteria for a Selected Group of Functional Disorders

Cited by

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Metadata

Authors
Kendler, K. S.
Affiliations
Virginia Commonwealth University (US)
Corresponding author
Kendler, Kenneth S.
Venue
American Journal of Psychiatry
Published
2016-08-01
Volume
173
Issue
8
Pages
771-780
ISSN
  • 0002-953X (ISSN-L)
  • 1535-7228
OpenAlex
W2346168897
Cited by
255
References
42
Citations by year
2026: 25 · 2025: 32 · 2024: 32 · 2023: 20 · 2022: 27 · 2021: 19 · 2020: 24 · 2019: 15 · 2018: 27 · 2017: 27 · 2016: 5
FWCI
153.04
Type
journal article
Language
en
Open access
Locations
  • American Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
  • Social Sciences › Psychology › Clinical Psychology › Psychology and Mental Health
Keywords
major depressive disorder, DSM-5 diagnostic criteria, melancholia, history of psychiatry, psychomotor symptoms, neurovegetative symptoms, depersonalization/derealization
MeSH terms
Attitude of Health Personnel, Curriculum, Major Depressive Disorder, Diagnosis, Differential, Education, Medical, Humans, Psychopathology, Research, Textbooks as Topic, United States, Diagnostic and Statistical Manual of Mental Disorders

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