Personalizing the Treatment of Substance Use Disorders
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The focus on opioid use in previous behavioral intervention studies may leave out other important comorbid conditions that impact patient-reported outcomes and long-term recovery.
“The focus on opioid use in these previous behavioral intervention studies may, however, leave out other important co-morbid conditions that significantly impact key patient-reported outcomes related to quality of life and likelihood of meaningful long-term recovery 8.”
From Effects of a trauma-informed mindful recovery program on comorbid pain, anxiety, and substance use during primary care buprenorphine treatment: A proof-of-concept study (2023) · cites this paper as [8]
In “Treating the Dimensions of Substance Use Disorder” (p. 114), Volkow discusses comorbid depression and insomnia, and argues that improving depression may benefit patients even without abstinence. This supports considering conditions beyond opioid use in assessing recovery, but the paper does not say that the previous behavioral intervention studies omitted those conditions or establish their effect on quality-of-life patient-reported outcomes. (LLM, conf=0.84)
Experimental — accuracy not yet measuredPsychosocial treatments for SUDs yield small to moderate benefits compared to inactive controls in the short term.
“psychosocial treatments yield small to moderate benefits compared to inactive controls in the short-term [39,40,41,42,43,44].”
From Navigating the Complex Intersection of Substance Use and Psychiatric Disorders: A Comprehensive Review (2024) · cites this paper as [42]
In “Treating the Dimensions of Substance Use Disorder” (page not specified), the paper says cognitive-behavioral treatments and contingency management have benefits for specific aspects of addiction. It does not quantify those benefits as small to moderate or compare them with inactive controls over the short term. (LLM, conf=0.86)
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- Authors
- Volkow, N. D.
- Affiliations
- National Institute on Drug Abuse (US)
- Corresponding author
- Volkow, Nora D.
- ORCID
- Volkow, Nora D.
- Venue
- American Journal of Psychiatry
- Published
- 2020-02-01
- Volume
- 177
- Issue
- 2
- Pages
- 113-116
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W3003347387
- Cited by
- 172
- References
- 17
- Citations by year
- 2026: 19 · 2025: 39 · 2024: 26 · 2023: 25 · 2022: 27 · 2021: 24 · 2020: 12
- FWCI
- 15.82
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- substance use disorders, personalized treatment
- MeSH terms
- Humans, Outcome Assessment, Health Care, Substance-Related Disorders, Precision Medicine
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