The DOI matches its Crossref record; 35 of the 36 references it cites were found in a registry or an index.
Behavioral Problems in Dementia Patients and Salivary Cortisol Patterns in Caregivers
Abstract
This study examines cortisol profiles in caregivers of dementia patients and their relationship to patients' behavioral problems. Salivary cortisol profiles and cortisol response to awakening were measured in 57 caregivers and 55 noncaregiver comparison subjects. Caregivers showed significantly higher levels of cortisol at the time of morning awakening than did comparison subjects, with a smaller increase after awakening. A higher cortisol awakening response was found in caregivers of patients with high versus low levels of behavioral and psychological symptoms of dementia (BPSD). Elevated morning cortisol levels could predispose caregivers to negative health consequences, with caregivers of patients with BPSD at greater risk.
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In the citing paper
“People with frontotemporal dementia are more likely to experience frequent and serious BPSD, e.g., agitation, disinhibition, apathy and eating abnormalities [125,126,127,128].”
From Relationship of Psychological Flexibility and Mindfulness to Caregiver Burden, and Depressive and Anxiety Symptoms in Caregivers of People with Dementia (2023) · cites this paper as [125]
In the citing paper
“chronic stress is associated with dysregulation of the HPA axis (e.g., in people caring for family members with dementia, de Vugt et al., 2005; Stalder et al., 2014).”
From A psychology of the human brain-gut-microbiome axis (2017) · cites this paper as de Vugt et al., 2005
Citations
Cites
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Cited by
Assessment and management of behavioral and psychological symptoms of dementia
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The cortisol awakening response (CAR): Facts and future directions
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Correlates of Physical Health of Informal Caregivers: A Meta-Analysis
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Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis
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Stress and Health: A Review of Psychobiological Processes
O'Connor, D. B., Thayer, J. F., & Vedhara, K. (2021) · Annual Review of Psychology · doi:10.1146/annurev-psych-062520-122331 · Cited by 948
Metadata
- Authors
- de Vugt, M. E., Nicolson, N. A., Aalten, P., Lousberg, R., Jolle, J., & Verhey, F. R. J.
- Affiliations
- Received December 19, 2002; revised October 9, 2003; accepted October 13, 2003. From the Department of Psychiatry and Neuropsychology, Brain and Behavior Institute, University of Maastricht, Maastricht, the Netherlands. Address correspondence to Professor Verhey, Department of Psychiatry and Neuropsychology, University Hospital of Maastricht, PO Box 616, 6200 MD Maastricht, the Netherlands; (E-mail).
- Maastricht University Medical Centre (NL)
- Venue
- The Journal of Neuropsychiatry and Clinical Neurosciences
- Published
- 2005-05
- Volume
- 17
- Issue
- 2
- Pages
- 201-207
- ISSN
- 0895-0172 (ISSN-L)
- 1545-7222
- OpenAlex
- W2100844017
- Cited by
- 136
- References
- 36
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 2 · 2022: 5 · 2021: 5 · 2020: 7 · 2019: 2 · 2018: 7 · 2017: 8 · 2016: 9 · 2015: 8 · 2014: 10 · 2013: 11 · 2012: 13
- FWCI
- 3.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neuropsychiatry (publishedVersion)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (publishedVersion)
- Research Publications (Maastricht University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Nursing › Research and Theory › Nursing care and research
- Keywords
- dementia, behavioral and psychological symptoms of dementia, caregivers, salivary cortisol, cortisol awakening response, caregiver stress
- MeSH terms
- Adult, Aged, Aged, 80 and over, Behavior, Circadian Rhythm, Dementia, Depression, Female, Humans, Hydrocortisone, Male, Middle Aged, Psychiatric Status Rating Scales, Saliva, Stress, Psychological, Caregivers
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- CoChat. (2026). Citation check: Behavioral Problems in Dementia Patients and Salivary Cortisol Patterns in Caregivers. https://app.cochat.ai/papers/10.1176/jnp.17.2.201
- The paper
- de Vugt, M. E., Nicolson, N. A., Aalten, P., Lousberg, R., Jolle, J., & Verhey, F. R. J. (2005). Behavioral Problems in Dementia Patients and Salivary Cortisol Patterns in Caregivers. The Journal of Neuropsychiatry and Clinical Neurosciences. https://doi.org/10.1176/jnp.17.2.201
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
