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The Emerging Link Between Autoimmune Disorders and Neuropsychiatric Disease
Open accessAbstract
Abnormal autoimmune activity has been implicated in a number of neuropsychiatric disorders. In this review, the authors discuss a newly recognized class of synaptic autoimmune encephalitides as well as behavioral and cognitive manifestations of systemic autoimmune diseases.
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“Rapidly progressive alterations of memory, behavior, cognition, and psychosis previously thought to be idiopathic or viral-induced are now known to be autoimmune.20-23”
From Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study (2013) · cites this paper as [21]
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Metadata
- Authors
- Kayser, M. S., & Dalmau, J.
- Affiliations
- University of Pennsylvania (US)
- Venue
- Journal of Neuropsychiatry
- Published
- 2011-02-01
- Volume
- 23
- Issue
- 1
- Pages
- 90-97
- ISSN
- 0895-0172 (ISSN-L)
- PMC
- PMC3086677
- OpenAlex
- W2122331073
- Cited by
- 133
- References
- 74
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 8 · 2023: 11 · 2022: 6 · 2021: 9 · 2020: 11 · 2019: 10 · 2018: 8 · 2017: 8 · 2016: 13 · 2015: 5 · 2014: 9 · 2013: 11 · 2012: 9
- FWCI
- 6.50
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Neuropsychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (CA89054, R01CA089054, R56CA089054)
- National Institute of Neurological Disorders and Stroke (NS068204, RC1NS068204, R01NS077851)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Autoimmune Neurological Disorders and Treatments
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Health Sciences › Medicine › Clinical Neurology › Peripheral Neuropathies and Disorders
- Keywords
- autoimmune disease, neuropsychiatric disorders, autoimmune encephalitis, behavioral manifestations, cognitive impairment, systemic autoimmune diseases
- MeSH terms
- Animals, Autoimmune Diseases, Mental Disorders, Brain, Encephalitis, Humans, Lupus Erythematosus, Systemic, Receptors, N-Methyl-D-Aspartate, Receptors, AMPA
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