The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Amygdala Volume in Adults with Posttraumatic Stress Disorder: A Meta-Analysis
Abstract
Posttraumatic stress disorder (PTSD) may be associated with structural abnormalities in the amygdala. To better characterize amygdala volume in PTSD, the authors conducted a meta-analysis comparing amygdala volumes in PTSD patients and comparison subjects. Using electronic databases, the authors found nine studies comparing amygdala volumes in adult subjects with PTSD with amygdala volumes in comparison subjects (participants unexposed to trauma and participants exposed to trauma but without PTSD). Results showed no significant differences in amygdala volumes between the groups. Within each group, the right amygdala was significantly larger than the left, indicating an asymmetrically lateralized amygdala volume that is preserved in trauma exposure and in PTSD.
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“Woon and Hedges (2009) through the analysis of nine studies comparing amygdala volumes among adults with PTSD and control groups consisting of people without PTSD, in which no significant difference in amygdala volume between these two groups were found.”
From Neuroimaging research in posttraumatic stress disorder – Focus on amygdala, hippocampus and prefrontal cortex (2019) · cites this paper as Woon and Hedges (2009)
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Neuroanatomical Correlates of PTSD: Risk, Resiliency, and Sequelae
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Metadata
- Authors
- Woon, F. L., & Hedges, D. W.
- Affiliations
- Brigham Young University (US)
- Venue
- The Journal of Neuropsychiatry and Clinical Neurosciences
- Published
- 2009-01
- Volume
- 21
- Issue
- 1
- Pages
- 5-12
- ISSN
- 0895-0172 (ISSN-L)
- 1545-7222
- OpenAlex
- W2027015546
- Cited by
- 120
- References
- 51
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 7 · 2022: 4 · 2021: 6 · 2020: 7 · 2019: 6 · 2018: 10 · 2017: 9 · 2016: 13 · 2015: 10 · 2014: 8 · 2013: 11 · 2012: 13
- FWCI
- 1.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neuropsychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Keywords
- post-traumatic stress disorder, amygdala volume, structural brain abnormalities, hemispheric lateralization, trauma exposure, neuroanatomy
- MeSH terms
- Adult, Amygdala, Female, Humans, Functional Laterality, Magnetic Resonance Imaging, Male, Middle Aged, Organ Size, Stress Disorders, Post-Traumatic, Stress, Psychological, Databases as Topic
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