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Cited by 330

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Medication noncompliance and substance abuse among patients with schizophrenia

·1996·Psychiatric Services

Abstract

OBJECTIVE: The study examined the effect of medication noncompliance and substance abuse on symptoms of schizophrenia. METHODS: Short-term inpatients with a diagnosis of schizophrenia were enrolled in a longitudinal outcomes study and continued to receive standard care after discharge. At baseline and six-month follow-up, Brief Psychiatric Rating Scale (BPRS) scores and data on subjects' reported medication compliance, drug and alcohol abuse, usual living arrangements, and observed side effects were obtained. The number of outpatient contacts during the follow-up period was obtained from medical records. Relationships between the dependent variables-medication noncompliance and follow-up BPRS scores-and the independent variables were analyzed using logistic and linear regression models. RESULTS: Medication noncompliance was significantly associated with substance abuse. Subjects who abused substances, had no outpatient contact, and were noncompliant with medication had significantly greater symptom severity than other groups. CONCLUSIONS: Substance abuse is strongly associated with medication noncompliance among patients with schizophrenia. The combination of substance abuse, medication noncompliance, and lack of outpatient contact appears to define a particularly high-risk group.

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Metadata

Venue
Psychiatric Services
Published
1996-08-01
Volume
47
Issue
8
Pages
853-858
ISSN
  • 0022-1597 (ISSN-L)
  • 1075-2730
  • 1557-9700
OpenAlex
W1629537514
Cited by
330
References
3
FWCI
10.17
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Medication noncompliance and substance abuse among patients with schizophrenia. https://app.cochat.ai/papers/10.1176/ps.47.8.853
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Medication noncompliance and substance abuse among patients with schizophrenia. (1996). Psychiatric Services. https://doi.org/10.1176/ps.47.8.853

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.